Apne ve nazal mukosiliyer klirens

ÇINAR, Fikret; evren, cenk

Apne ve nazal mukosiliyer klirens

Cenk EVREN, (İstanbul Medilife Beylikdüzü Hastanesi, Kulak Burun Boğaz Bölümü, İstanbul, Türkiye)

Fikret ÇINAR (İstanbul Bilim Üniversitesi, Tıp Fakültesi, Kulak Burun Boğaz Anabilim Dalı, İstanbul, Türkiye)

Kulak Burun Boğaz Uygulamaları

1 0

Yıl: 2015 Cilt: 3 Sayı: 2 Sayfa Aralığı: 62 - 67 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Apne ve nazal mukosiliyer klirens

Öz:

Amaç: Bu çalışmada tıkayıcı uyku apne sendromu ve basit horlamahastalarında nazal mukosiliyer klirens zamanı karşılaştırıldı. Hastalar ve Yöntemler: Ekim 2009 - Nisan 2010 tarihleriarasında kliniğimize horlama yakınması ile başvuran ve klinikgereklilik yüzünden polisomnografi yapılan 50 hasta (40 erkek,10 kadın; ort. yaş 46.22 yıl; dağılım 29-67 yıl) çalışmaya dahiledildi. Hastalar apne hipopne indeksine (A Hİ) göre iki grubaayrıldı. A Hİ skoru <5 olanlar basit horlama grubu (n=23),A Hİ skoru >5 olanlar apne grubu (n=27) olarak kayıt edildi.Ayrıca 29 sağlıklı gönüllü (16 erkek, 13 kadın; ort. yaş 39.4 yıl;dağılım 21-61 yıl) ile bir kontrol grubu oluşturuldu. Sakarintesti polisomnografinin yapılacağı gece yatmadan önce ve sabahkalkınca ilk yarım saat içinde uygulandı. Bulgular: Basit horlama ve apne gruplarındaki hastaların yaşortalamaları arasında istatistiksel olarak anlamlı bir farklılık yoktu(p>0.05). Basit horlama grubunda ortalama klirens zamanı akşam25.7 dk, sabah 23.2 dk idi. Apne grubunda ortalama klirens zamanıakşam 19.0 dk, sabah 19.8 dk idi. Kontrol grubunda ortalama klirenszamanı akşam 24.2 dk, sabah 24.1 dk idi. Buna göre, basit horlamave apne grupları arasında sabah ve akşam klirens ölçümlerindeistatistiksel olarak anlamlı bir farklılık bulunmadı (p=0.102,p=0.301). Basit horlama ve apne grupları arasında klirens ölçümleriaçısından istatistiksel olarak anlamlı bir farklılık yoktu (p=0.522,p=0.596). Hafif, orta ve ağır apne grupları ile kontrol grubuarasında mukosiliyer klirens zamanı açısından anlamlı farklılıkyoktu (p=0.323, p=0.274). Sonuç: Çalışmamızın sonucunda basit horlama ve apne gruplarıarasında sabah ve akşam klirens ölçümleri açısından istatistikselolarak anlamlı bir farklılık bulunmadı. Ayrıca, her bir grup içindeklirens ölçümleri açısından istatistiksel olarak anlamlı bir farklılıkyoktu.

Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel

Apnea and nasal mucociliary clearance

Öz:

Objectives: This study aims to compare the nasal mucociliary clearancetime in patients with obstructive sleep apnea syndrome and simple snoring. Patients and Methods: Fifty patients (40 males, 10 females; mean age46.22 years; range 29 to 67 years) who were admitted to our clinic withcomplaint of snoring and performed polysomnography due to clinicalnecessity between October 2009 and April 2010 were included in thestudy. Patients were divided into two groups according to apnea hypopneaindex (AHI). Patients with AHI score <5 were recorded as simple snoringgroup (n=23), and with AHI score >5 as apnea group (n=27). Also, a controlgroup of 29 healthy volunteers (16 males, 13 females; mean age 39.4 years;range 21 to 61 years) was created. Saccharine test was performed beforebedtime in the night during which the polysomnography was to beconducted and within the first half hour after waking up in the morning. Results: There was no statistically significant difference between themean age of patients in the simple snoring and apnea groups (p>0.05).In the simple snoring group, mean clearance time was 25.7 min. in theevening and 23.2 min. in the morning. In the apnea group, mean clearancetime was 19.0 min. in the evening and 19.8 min. in the morning. In thecontrol group, mean clearance time was 24.2 minutes in the evening and24.1 minutes in the morning. Accordingly, no statistically significantdifference was detected between the simple snoring and apnea groups inthe morning and evening measurements of clearance (p=0.102, p=0.301).There was no statistically significant difference between the simplesnoring and apnea groups in terms of the measurements of clearance(p=0.522, p=0.596). There was no statistically significant differencebetween mild, moderate and severe apnea groups with control group interms of mucociliary clearance time (p=0.323, p=0.274). Conclusion: As a result of our study, no statistically significantdifference was detected between the simple snoring and apnea groupsin terms of morning and evening clearance measurements. Also, therewas no statistically significant difference within each group in terms ofclearance measurements.

Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	evren c, ÇINAR F (2015). Apne ve nazal mukosiliyer klirens. , 62 - 67.
Chicago	evren cenk,ÇINAR Fikret Apne ve nazal mukosiliyer klirens. (2015): 62 - 67.
MLA	evren cenk,ÇINAR Fikret Apne ve nazal mukosiliyer klirens. , 2015, ss.62 - 67.
AMA	evren c,ÇINAR F Apne ve nazal mukosiliyer klirens. . 2015; 62 - 67.
Vancouver	evren c,ÇINAR F Apne ve nazal mukosiliyer klirens. . 2015; 62 - 67.
IEEE	evren c,ÇINAR F "Apne ve nazal mukosiliyer klirens." , ss.62 - 67, 2015.
ISNAD	evren, cenk - ÇINAR, Fikret. "Apne ve nazal mukosiliyer klirens". (2015), 62-67.

APA	evren c, ÇINAR F (2015). Apne ve nazal mukosiliyer klirens. Kulak Burun Boğaz Uygulamaları, 3(2), 62 - 67.
Chicago	evren cenk,ÇINAR Fikret Apne ve nazal mukosiliyer klirens. Kulak Burun Boğaz Uygulamaları 3, no.2 (2015): 62 - 67.
MLA	evren cenk,ÇINAR Fikret Apne ve nazal mukosiliyer klirens. Kulak Burun Boğaz Uygulamaları, vol.3, no.2, 2015, ss.62 - 67.
AMA	evren c,ÇINAR F Apne ve nazal mukosiliyer klirens. Kulak Burun Boğaz Uygulamaları. 2015; 3(2): 62 - 67.
Vancouver	evren c,ÇINAR F Apne ve nazal mukosiliyer klirens. Kulak Burun Boğaz Uygulamaları. 2015; 3(2): 62 - 67.
IEEE	evren c,ÇINAR F "Apne ve nazal mukosiliyer klirens." Kulak Burun Boğaz Uygulamaları, 3, ss.62 - 67, 2015.
ISNAD	evren, cenk - ÇINAR, Fikret. "Apne ve nazal mukosiliyer klirens". Kulak Burun Boğaz Uygulamaları 3/2 (2015), 62-67.