Nilüfer Gülmen İMİR
(Akdeniz Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Anabilim Dalı, Antalya, Türkiye)
AYŞE GÜL NASIRCILAR
(Girilmedi)
HAKAN AKÇA
(Girilmedi)
Tekinalp GELEN
(Girilmedi)
Mehmet ÖĞÜŞ
(Girilmedi)
Şeyda KARAVELİ
(Girilmedi)
Osman Nidai ÖZEŞ
(Girilmedi)
Yıl: 2002Cilt: 32Sayı: 3ISSN: 1300-0144 / 1303-6165Sayfa Aralığı: 195 - 199İngilizce

36 0
IFN-gamma-mediated transcriptional induction of the IDO (Indolamine 2,3-dioxygenase) gene requires activity of p68/PKR protein kinase
Fen > Tıp > Cerrahi
DergiDiğerErişime Açık
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  • 18. …zeß ON and Taylor MW. Reversal of IFN-gamma-resistant phenotype by poly I: C: possible involvement of ISGF2 (IRF1) in IFN-gamma-mediated induction of the IDO gene. J of Interferon Res 14 (1): 25-32, 1994. 19. Feng GS and Taylor MW. Interferon gamma resistant mutants are defective in the induction of indolamine 2,3- dioxygenase. Proc Natl Acad Sci USA 86: 7144-48, 1989. 20. Blair LA, Maggi LB, Scarim AL, Corbett JA. Role of interferon regulatory 1 in double stranded RNA-induced iNOS expression by mouse Islets. J Biol Chem. 277: 359-365, 2002. 21. Goh KC, Haque SJ, and Williams BR. P38 MAP kinase is required for Stat1 serine phosphorylation and transcriptional activation by interferons. EMBO J. 18: 5601-5608, 1999. 22. Howarth CM. Stat proteins and transcriptional responses to extracellular signals. Trends Biochem Sci. 25: 496- 502. 2000. 23. Gil J, Alcami J, and Esteban M. Induction of apoptosis by double stranded RNA-dependent protein kinase PKR involves the a-subunit of eucaryotic translation initiation factor 2 and Nf-kB. Mol Cell Biol. 19: 4653-4663. 1999. 24. Kumar A, Yang YL, Flati V, Kadereit S, Deb A, Haque J, Reis L, Weissman C, and Williams BR. Deficient cytokine signaling in mouse embryo fibroblast with a targeted deletion of the PKR gene: role of IRF1 and NF-kB. EMBO J. 16: 406- 416. 1997. 25. Konan KV, and Taylor MW. Importance of the two IFN-stimulated response element (ISRE) sequences in the regulation of the human indolamine 2-3-dioxygenase gene. J Biol Chem. 271: 19140- 19145, 1996. 26. Chon SY, Hassanain HH, and Gupta SL. Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferon-gamma-inducible expression of human indolamine 2,3Ðdioxygenase gene. J Biol Chem. 271: 17247-17252, 1996.

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