Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines

ÖZEŞ, Osman N.; AKÇA, Hakan

Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines

Hakan AKÇA, (Akdeniz Üniversitesi, Fen Edebiyat Fakültesi, Biyoloji Anabilim Dalı, Antalya, Türkiye)

Osman N. ÖZEŞ (Girilmedi)

Turkish Journal of Medical Sciences

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Yıl: 2002 Cilt: 32 Sayı: 2 Sayfa Aralığı: 127 - 132 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines

Öz:

Cervical carcinoma is one type of cancer with a high mortality rate in females. In this study, we investigated the cytotoxic effects of TNF-beta, 5-FU and their combinations on human cervical carcinoma cell lines, ME180 and HeLa. The highest degree of cytotoxic effect was obtained with 5-FU on both cell lines. While high concentrations of TNF-beta showed cytotoxic effects on both cell lines, the lowest dose induced growth. Combination treatment of 5-FU and TNF-beta gave a slightly higher cytotoxic and antiproliferative response compared to individual use of 5-FU and TNF-beta on both cell lines.

Anahtar Kelime: Cervix Neoplasms Cytotoxicity Fluorouracil Tumor Necrosis Factor

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Diğer Erişim Türü: Erişime Açık

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APA	AKÇA H, ÖZEŞ O (2002). Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. , 127 - 132.
Chicago	AKÇA Hakan,ÖZEŞ Osman N. Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. (2002): 127 - 132.
MLA	AKÇA Hakan,ÖZEŞ Osman N. Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. , 2002, ss.127 - 132.
AMA	AKÇA H,ÖZEŞ O Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. . 2002; 127 - 132.
Vancouver	AKÇA H,ÖZEŞ O Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. . 2002; 127 - 132.
IEEE	AKÇA H,ÖZEŞ O "Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines." , ss.127 - 132, 2002.
ISNAD	AKÇA, Hakan - ÖZEŞ, Osman N.. "Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines". (2002), 127-132.

APA	AKÇA H, ÖZEŞ O (2002). Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. Turkish Journal of Medical Sciences, 32(2), 127 - 132.
Chicago	AKÇA Hakan,ÖZEŞ Osman N. Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. Turkish Journal of Medical Sciences 32, no.2 (2002): 127 - 132.
MLA	AKÇA Hakan,ÖZEŞ Osman N. Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. Turkish Journal of Medical Sciences, vol.32, no.2, 2002, ss.127 - 132.
AMA	AKÇA H,ÖZEŞ O Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. Turkish Journal of Medical Sciences. 2002; 32(2): 127 - 132.
Vancouver	AKÇA H,ÖZEŞ O Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines. Turkish Journal of Medical Sciences. 2002; 32(2): 127 - 132.
IEEE	AKÇA H,ÖZEŞ O "Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines." Turkish Journal of Medical Sciences, 32, ss.127 - 132, 2002.
ISNAD	AKÇA, Hakan - ÖZEŞ, Osman N.. "Antitumor effects of TNF-beta, 5-FU and their combinations on cervical carcinoma cell lines". Turkish Journal of Medical Sciences 32/2 (2002), 127-132.