Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature
Yıl: 2015 Cilt: 21 Sayı: 3 Sayfa Aralığı: 72 - 75 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature
Öz: Amaç: Hepatit A dünyada en sık izlenen enfeksiyon hastalıklarındandır. Bulaş fekal-oral yol ile olması nedeniyle hepatit A virüs (HAV) enfeksiyonu prevalansı bölgenin ekonomik gelişimi ile paraleldir. Bu çalışmada, eğitim ve araştırma hastanemize başvuran farklı yaş gruplarından hastalarda hepatit A seroprevalansının saptanması amaçlanmıştır.Gereç ve Yöntemler: Ocak 2009-Haziran 2013 yılları arasında Ahi Evran Üniversitesi Eğitim ve Araştırma Hastanesi'ne başvuran hastaların serum örneklerinde Cobas 6000 (Roche, Germany) cihazı kullanılarak kemiluminesans mikropartikül immünoassay metodu ile anti-HAV IgM ve IgG antikorları incelendi. Hastalar 0-5, 6-10, 11-20, 21-30, 31-40, 41-50, 51-60, 61-70, ve 71 yaş üzeri olarak sınıflandırıldı ve değerlendirildi. İstatistiksel analiz SPSS 15.0 software kullanılarak yapıldı ve p değeri <0,05 altında ise anlamlı olarak kabul edildi.Bulgular: Anti-HAV IgM ve anti-HAV IgG pozitifliği sırasıyla %0,5 ve %87,3 idi. Anti-HAV IgM pozitifliği en yüksek 41-50 yaş grubunda, en düşük 0-5 ve 11-20 yaş grubunda belirlendi. Anti-HAV IgG pozitifliği ise en yüksek 0-5 yaş grubunda (%99,7), en düşük 11-30 yaş grubunda (%61) izlendi. Anti-HAV IgM pozitifliğine en sık Ağustos, Eylül ve Aralık ayında rastlandı.Sonuç: Bu çalışmada HAV prevalansı ülkemizde yapılan diğer çalışmalarla benzer bulunmuştur. HAV enfeksiyon prevalansının azaltılmasında aşılama programlarının yanı sıra sanitasyon uygulamalarının iyileştirilmesi gereklidir.
Anahtar Kelime: Konular:
Kırşehir Bölgesinde Farklı Yaş Gruplarında Hepatit A Virüs Seroprevalans Oranları ve Literatürün Değerlendirilmesi
Öz: Objective: Hepatitis A is one of the most common infectious diseases in the world. The prevalence of hepatitis A virus (HAV) infection correlates with the economic development of a region due to the transmission by fecal-oral route. In this study, we aimed to determine the seroprevalence of hepatitis A among patients of different age groups admitted to a training and research hospital.Materials and Methods: During the study period, January 2009-June 2013, serum samples of patients admitted to Ahi Evran University Research and Training Hospital were tested for anti-HAV IgM and IgG antibodies by the chemiluminescent microparticle immunoassay using Cobas 6000 (Roche, Germany) analyzer. The patients were divided into the age groups: 0-5, 6-10, 11-20, 21-30, 31-40, 41-50, 51-60, 61-70, and 71 years and over. The statistical analysis was performed using SPSS 15.0 software and a p value of less than 0.05 was considered statistically significant.Results: Anti-HAV IgM and anti-HAV IgG positivity rates were 0.5% and 87.3%, respectively. The highest anti-HAV IgM positivity was detected in the 41-50 age group and the lowest in the 0-5 and 11-20 age groups. The highest anti-HAV IgG positivity rate was observed in patients 0-5 years of age (99.7%) and lowest in those 11-30 years of age (61%). Anti-HAV IgM positivity rate was highest in August, September and December.Conclusion: In this study, the prevalence of HAV infection was found to be similar to that in previous studies performed in our country. It is clear that implementation of vaccination programs as well as improving sanitation practices are essential for decreasing the prevalence of the infection.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA | demir t, turan m (2015). Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. , 72 - 75. |
Chicago | demir tulin,turan meral Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. (2015): 72 - 75. |
MLA | demir tulin,turan meral Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. , 2015, ss.72 - 75. |
AMA | demir t,turan m Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. . 2015; 72 - 75. |
Vancouver | demir t,turan m Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. . 2015; 72 - 75. |
IEEE | demir t,turan m "Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature." , ss.72 - 75, 2015. |
ISNAD | demir, tulin - turan, meral. "Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature". (2015), 72-75. |
APA | demir t, turan m (2015). Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. Viral Hepatitis Journal, 21(3), 72 - 75. |
Chicago | demir tulin,turan meral Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. Viral Hepatitis Journal 21, no.3 (2015): 72 - 75. |
MLA | demir tulin,turan meral Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. Viral Hepatitis Journal, vol.21, no.3, 2015, ss.72 - 75. |
AMA | demir t,turan m Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. Viral Hepatitis Journal. 2015; 21(3): 72 - 75. |
Vancouver | demir t,turan m Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature. Viral Hepatitis Journal. 2015; 21(3): 72 - 75. |
IEEE | demir t,turan m "Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature." Viral Hepatitis Journal, 21, ss.72 - 75, 2015. |
ISNAD | demir, tulin - turan, meral. "Seroprevalence Rates of Hepatitis A Virus in Different Age Groups in the Province of Kırşehir and a Review of the Literature". Viral Hepatitis Journal 21/3 (2015), 72-75. |