Yıl: 2013 Cilt: 28 Sayı: 1 Sayfa Aralığı: 32 - 37 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis

Öz:
Amaç: Bu çalışmada romatoid artriti (RA) olan İranlı hastalarda depresyon prevalansı ve şiddeti arasındaki ilişki araştırıldı ve kullanışlı klinik depresyon semptomlarının korelasyonları tespit edildi.Hastalar ve yöntemler: Semnan'da Fatemieh ve Amir hastanelerinin romatoloji kliniklerinde Amerikan Romatoloji Derneği (ACR) RA kriterlerini karşılayan 140 hasta (28 erkek, 112 kadın; ort. yaş 46.4±13.5 yıl; dağılım 19-80 yıl) çalışmaya dahil edildi. Hastalar aktif RA olanlar (n=56) ve inaktif RA olanlar (n=84) olmak üzere iki gruba ayrıldı. Romatolojik hastalık öyküsü olmayan ve hastanede çalışan 140 yaş ve cinsiyet uyumlu sağlıklı gönüllü de kontrol grubu olarak belirlendi. Depresyon semptomları, Beck Depresyon Envanteri II'nin (BDI-II) İran versiyonu kullanılarak değerlendirildi.Bulgular: Aktif RA grubunda hafif ila orta düzeyde depresyonun genel prevalansı %30.4, inaktif RA grubunda %22.6, kontrol grubunda ise %12.1 idi. Şiddetli depresyon yalnızca iki kişide görüldü. Bunlardan biri aktif RA grubunda, diğeri ise kontrol grubundaydı. Çok değişkenli analiz eritrosit sedimentasyon hızı ve C-reaktif protein düzeylerinin yanı sıra kadın cinsiyetinin de RA hastalarında depresyon gelişimi ile ilişkili olduğunu gösterdi.Sonuç: Aktif RA hastalarında hafif ila orta düzeyde depresyonun genel prevalansı fark edilebilir düzeyde daha yüksekti. Bu durum, cinsiyet ve serum inflamatuvar belirteçleri ile son derece ilişkili olabilir
Anahtar Kelime:

Konular: Romatoloji

Romatoid Artrit Hastalarında Depresyonun Sıklığı ve Ana Belirleyicileri

Öz:
Objectives: This study aims to investigate the relationship between the prevalence of depression and its severity in Iranian patients with rheumatoid arthritis (RA) and to identify useful clinical correlations of the depressive symptoms. Patients and methods: One hundred and forty patients (28 males, 112 females; mean age 46.4±13.5; range 19-80 years) who met the American College of Rheumatology (ACR) criteria for RA in the outpatient rheumatology clinic of the Fatemieh and Amir hospitals in Semnan were included. The patients were divided into two groups including patients with active RA (n=56) and with inactive RA (n=84). One hundred and forty age and gender-matched healthy volunteers who work at the hospital without a history of rheumatological disorder were also included as controls. Depressive symptoms were assessed using the Iranian version of the Beck Depression Inventory II (BDI-II). Results: The overall prevalence of mild-to-moderate depression was 30.4% in the active RA group, 22.6% in the inactive RA group, and 12.1% in the control group. Severe depression was only observed in two of the subjects. One of those was in the active RA group, and the other was in the control group. Multivariate analysis showed that female gender as well as levels of erythrocyte sedimentation rate and C-reactive protein were associated with the development of depression in RA patients. Conclusion: The overall prevalence of mild-to-moderate depression in patients with active RA is notably higher. Thiscan be strongly associated with the gender and serum inflammatory markers.
Anahtar Kelime:

Konular: Romatoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA BEHNAM B, MOGHIMI J, GHORBANI R, GHAHREMANFARD F (2013). The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. , 32 - 37.
Chicago BEHNAM Behnaz,MOGHIMI Jamileh,GHORBANI Raheb,GHAHREMANFARD Farahnaz The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. (2013): 32 - 37.
MLA BEHNAM Behnaz,MOGHIMI Jamileh,GHORBANI Raheb,GHAHREMANFARD Farahnaz The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. , 2013, ss.32 - 37.
AMA BEHNAM B,MOGHIMI J,GHORBANI R,GHAHREMANFARD F The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. . 2013; 32 - 37.
Vancouver BEHNAM B,MOGHIMI J,GHORBANI R,GHAHREMANFARD F The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. . 2013; 32 - 37.
IEEE BEHNAM B,MOGHIMI J,GHORBANI R,GHAHREMANFARD F "The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis." , ss.32 - 37, 2013.
ISNAD BEHNAM, Behnaz vd. "The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis". (2013), 32-37.
APA BEHNAM B, MOGHIMI J, GHORBANI R, GHAHREMANFARD F (2013). The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. Turkish Journal of Rheumatology(.)Archives of Rheumatology, 28(1), 32 - 37.
Chicago BEHNAM Behnaz,MOGHIMI Jamileh,GHORBANI Raheb,GHAHREMANFARD Farahnaz The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. Turkish Journal of Rheumatology(.)Archives of Rheumatology 28, no.1 (2013): 32 - 37.
MLA BEHNAM Behnaz,MOGHIMI Jamileh,GHORBANI Raheb,GHAHREMANFARD Farahnaz The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. Turkish Journal of Rheumatology(.)Archives of Rheumatology, vol.28, no.1, 2013, ss.32 - 37.
AMA BEHNAM B,MOGHIMI J,GHORBANI R,GHAHREMANFARD F The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. Turkish Journal of Rheumatology(.)Archives of Rheumatology. 2013; 28(1): 32 - 37.
Vancouver BEHNAM B,MOGHIMI J,GHORBANI R,GHAHREMANFARD F The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis. Turkish Journal of Rheumatology(.)Archives of Rheumatology. 2013; 28(1): 32 - 37.
IEEE BEHNAM B,MOGHIMI J,GHORBANI R,GHAHREMANFARD F "The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis." Turkish Journal of Rheumatology(.)Archives of Rheumatology, 28, ss.32 - 37, 2013.
ISNAD BEHNAM, Behnaz vd. "The Frequency and Major Determinants of Depression in Patients with Rheumatoid Arthritis". Turkish Journal of Rheumatology(.)Archives of Rheumatology 28/1 (2013), 32-37.