The relationship between epicardial adipose tissue and P wave and QT dispersions

BALCIOĞLU, AKİF SERHAT; ERDOĞAN, Turan; KARADAĞ, Zakir; BOSTAN, Mehmet; Duman, Handan; ŞATIROĞLU, Ömer; çiçek, yüksel gülen; Durakoglugil, Murtaza Emre; DOĞAN, Sıtkı

The relationship between epicardial adipose tissue and P wave and QT dispersions

Yüksel ÇİÇEK, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Sıtkı DOĞAN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Murtaza Emre DURAKOĞLUGİL, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Akif Serhat BALCIOĞLU, (Başkent Üniversitesi Tıp Fakültesi, Kardiyoloji Bölümü, Ankara, Türkiye)

Turan ERDOĞAN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Ömer ŞATIROĞLU, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Zakir KARADAĞ, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Hakan DUMAN, (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Mehmet BOSTAN (Recep Tayyip Erdoğan Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Rize, Türkiye)

Türk Kardiyoloji Derneği Arşivi

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Yıl: 2015 Cilt: 43 Sayı: 7 Sayfa Aralığı: 621 - 629 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The relationship between epicardial adipose tissue and P wave and QT dispersions

Öz:

Amaç: Epikardiyal adipoz doku (EAD) kalpte pek çok endok- rin ve parakrin etkiye sahip olan çeşitli enflamatuvar ve atero- jenik ajanları salgılar. Bu çalışmada, EADnin elektrokardiyo- gafinin (EKG) basit, non-invaziv aritmi belirteçleri olan QT veP dalga dispersiyonu (QTd, PDd) üzerine etkisini araştırmayıplanladık. Yöntemler: Kesitsel yapıda çalışmamıza koroner arterle- ri normal 70 hasta alındı. Bu hastalara 12 derivasyon EKG,ekokardiyografi, biyokimyasal çalışmalar yapılarak, QTd, PDdve EAD kalınlığı hesaplandı. Bulgular: Ortanca EAD 4.1 mm olarak bulundu. EAD yaş(r=0.412, p<0.001), vücut ağırlığı (r=0.262, p=0.028), bedenkitle indeksi (r=0.396, p<0.001), sol atriyum boyutu (r=0.518,p<0.001), açlık plazma glukozu (r=0.245, p=0.041), maksi- mum P dalga süresi (r=0.343, p=0.004), minimum P dalgasüresi (r=0.275, p=0.021) ve PDd (r=0.265, p=0.026) ile ko- releydi. QTd ile çalışılan parametreler arasında ilişki saptan- madı. Ancak PDd; EAD kalınlığı (r=0.265, p=0.026), sol atri- yum boyutu (r=0.483, p<0.001) ve trigliserit düzeyi (r=0.267,p=0.028) ile ilişkiliydi. Çok değişkenli analiz sol atriyum bo- yutunun PDdnin tek bağımsız belirleyicisi olduğunu ortayakoydu. Sonuç: Çalışmamızda EAD ile PDd arasında anlamlı bir ilişkisaptadık. Her ne kadar EAD hem PDd ve hem de sol atriyumboyutu ile ilişkili ise de, sol atriyum boyutu, koroner arterle- ri normal hastalarda atriyum fibrilasyonu riski için EADdendaha önemli gibi görülmektedir.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Epikardiyal adipoz dokunun P dalga ve QT dispersiyonu ile ilişkisi

Öz:

Objective: Epicardial adipose tissue (EAT) secretes various pro- inflammatory and atherogenic mediators that have several en- docrine and paracrine effects on heart. This study investigatedthe influence of EAT on QT and P wave dispersions (QTd, PWd),as simple, non-invasive tools of proarrhythmia on surface ECG. Methods: This was a cross-sectional study and included70 patients with normal coronary arteries who underwent12-derivation electrocardiography, echocardiography and bio- chemical examinations in order for QTd, PWd, and EAT thick- ness to be measured. Results: Median EAT thickness was 4.1 mm. Correlationanalyses revealed that EAT was significantly associated withage (r=0.412, p<0.001), weight (r=0.262, p=0.028), bodymass index (r=0.396, p<0.001), left atrium diameter (r=0.518,p<0.001), fasting plasma glucose (r=0.245, p=0.041), maxi- mum P wave duration (r=0.343, p=0.004), minimum P wave du- ration (r=0.275, p=0.021) and PWd (r=0.265, p=0.026). No rela- tion was found between study parameters and QTd. However,P wave dispersion was significantly related to EAT thickness(r=0.265, p=0.026), left atrium diameter (r=0.483, p<0.001),and the triglyceride levels (r=0.267, p=0.028). Multiple linearregression analyses revealed left atrial diameter as the only in- dependent predictor of PWd. Conclusion: A significant association between EAT and PWdwas demonstrated in the study. While EAT is related to bothincreased PWd and left atrial size, left atrial diameter seemsto be more important than EAT for prediction of atrial fibrilla- tion (AF) in patients with normal coronary arteries.

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	çiçek y, DOĞAN S, Durakoglugil M, BALCIOĞLU A, ERDOĞAN T, ŞATIROĞLU Ö, KARADAĞ Z, Duman H, BOSTAN M (2015). The relationship between epicardial adipose tissue and P wave and QT dispersions. , 621 - 629.
Chicago	çiçek yüksel gülen,DOĞAN Sıtkı,Durakoglugil Murtaza Emre,BALCIOĞLU AKİF SERHAT,ERDOĞAN Turan,ŞATIROĞLU Ömer,KARADAĞ Zakir,Duman Handan,BOSTAN Mehmet The relationship between epicardial adipose tissue and P wave and QT dispersions. (2015): 621 - 629.
MLA	çiçek yüksel gülen,DOĞAN Sıtkı,Durakoglugil Murtaza Emre,BALCIOĞLU AKİF SERHAT,ERDOĞAN Turan,ŞATIROĞLU Ömer,KARADAĞ Zakir,Duman Handan,BOSTAN Mehmet The relationship between epicardial adipose tissue and P wave and QT dispersions. , 2015, ss.621 - 629.
AMA	çiçek y,DOĞAN S,Durakoglugil M,BALCIOĞLU A,ERDOĞAN T,ŞATIROĞLU Ö,KARADAĞ Z,Duman H,BOSTAN M The relationship between epicardial adipose tissue and P wave and QT dispersions. . 2015; 621 - 629.
Vancouver	çiçek y,DOĞAN S,Durakoglugil M,BALCIOĞLU A,ERDOĞAN T,ŞATIROĞLU Ö,KARADAĞ Z,Duman H,BOSTAN M The relationship between epicardial adipose tissue and P wave and QT dispersions. . 2015; 621 - 629.
IEEE	çiçek y,DOĞAN S,Durakoglugil M,BALCIOĞLU A,ERDOĞAN T,ŞATIROĞLU Ö,KARADAĞ Z,Duman H,BOSTAN M "The relationship between epicardial adipose tissue and P wave and QT dispersions." , ss.621 - 629, 2015.
ISNAD	çiçek, yüksel gülen vd. "The relationship between epicardial adipose tissue and P wave and QT dispersions". (2015), 621-629.

APA	çiçek y, DOĞAN S, Durakoglugil M, BALCIOĞLU A, ERDOĞAN T, ŞATIROĞLU Ö, KARADAĞ Z, Duman H, BOSTAN M (2015). The relationship between epicardial adipose tissue and P wave and QT dispersions. Türk Kardiyoloji Derneği Arşivi, 43(7), 621 - 629.
Chicago	çiçek yüksel gülen,DOĞAN Sıtkı,Durakoglugil Murtaza Emre,BALCIOĞLU AKİF SERHAT,ERDOĞAN Turan,ŞATIROĞLU Ömer,KARADAĞ Zakir,Duman Handan,BOSTAN Mehmet The relationship between epicardial adipose tissue and P wave and QT dispersions. Türk Kardiyoloji Derneği Arşivi 43, no.7 (2015): 621 - 629.
MLA	çiçek yüksel gülen,DOĞAN Sıtkı,Durakoglugil Murtaza Emre,BALCIOĞLU AKİF SERHAT,ERDOĞAN Turan,ŞATIROĞLU Ömer,KARADAĞ Zakir,Duman Handan,BOSTAN Mehmet The relationship between epicardial adipose tissue and P wave and QT dispersions. Türk Kardiyoloji Derneği Arşivi, vol.43, no.7, 2015, ss.621 - 629.
AMA	çiçek y,DOĞAN S,Durakoglugil M,BALCIOĞLU A,ERDOĞAN T,ŞATIROĞLU Ö,KARADAĞ Z,Duman H,BOSTAN M The relationship between epicardial adipose tissue and P wave and QT dispersions. Türk Kardiyoloji Derneği Arşivi. 2015; 43(7): 621 - 629.
Vancouver	çiçek y,DOĞAN S,Durakoglugil M,BALCIOĞLU A,ERDOĞAN T,ŞATIROĞLU Ö,KARADAĞ Z,Duman H,BOSTAN M The relationship between epicardial adipose tissue and P wave and QT dispersions. Türk Kardiyoloji Derneği Arşivi. 2015; 43(7): 621 - 629.
IEEE	çiçek y,DOĞAN S,Durakoglugil M,BALCIOĞLU A,ERDOĞAN T,ŞATIROĞLU Ö,KARADAĞ Z,Duman H,BOSTAN M "The relationship between epicardial adipose tissue and P wave and QT dispersions." Türk Kardiyoloji Derneği Arşivi, 43, ss.621 - 629, 2015.
ISNAD	çiçek, yüksel gülen vd. "The relationship between epicardial adipose tissue and P wave and QT dispersions". Türk Kardiyoloji Derneği Arşivi 43/7 (2015), 621-629.