The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury

YAŞAR, Ayşe Saatcı; Yasar, Evren; kesikburun, serdar; YAZICIOĞLU, Kamil; TEKİN, Levent; GÜZELKÜÇÜK, Ümüt; ALACA, RIDVAN; YILMAZ, Bilge; Aydemir, Koray; GOKTEPE, Ahmet Salim; MÖHÜR, Haydar

The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury

Evren YAŞAR, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Bilge YILMAZ, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Ayşe Saatcı YAŞAR, (Atatürk Eğitim ve Araştırma Hastanesi, Kardiyoloji Kliniği, Ankara, Türkiye)

Serdar KESİKBURUN, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Ümüt GÜZELKÜÇÜK, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Koray AYDEMİR, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Levent TEKİN, (Gülhane Askeri Tıp Akademisi Haydarpaşa Eğitim Hastanesi, Fiziksel Tıp ve Rehabilitasyon Kliniği, İstanbul.Türkiye)

Ahmet Salim GOKTEPE, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Rıdvan ALACA, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Kamil YAZICIOĞLU, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

Haydar MÖHÜR, (Gülhane Askeri Tıp Akademisi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, Türk Silahlı Kuvvetleri Rehabilitasyon Merkezi, Ankara, Türkiye)

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Gülhane Tıp Dergisi

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Yıl: 2015 Cilt: 57 Sayı: 1 Sayfa Aralığı: 5 - 10 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury

Öz:

Kronik spinal kord yaralı hastalarda otonomik disfonksiyonun QT dispersiyonu üzerine etkisi Amaç: Spinal kord yaralı(SKY) hastalarda otonomik disfonksiyonun ventriküler aritmilerin belirteci olan QT dispersiyonu üzerene etkisini inceleme ve hem istirahat hem de ürodinamik test sırasında aritmi riskini değerlendirmek. Materyal ve Metod: Bu prospektif çalışmaya 30 travmatik SKY ve 27 sağlıklı birey alınmıştır. Her iki gruptaki hastalara rutin fizik muayene ve 12 elektrotlu elektrokardiyografi(EKG) uygulanmıştır. Hasta grupta kan basıncı ve EKG kayıtları ürodinamik değerlendirme sırasında da uygulandı. QT intervalinin ölçümleri 2 kör araştırmacı tarafından yapıldı. QT ve düzeltilmiş QT (QTd) hesaplandı. SKY hastalar yaralanma seviyelerine ve ağırlığına gore ve ürodiamik ve otonomik testler sırasındaki otonomik disfonksiyonunun oluşumu muakayese edildi. Bulgular: QT ve QTd dispersiyon değerleri SKY hastalarda kontrollere daha yüksek idi. QT ve QTd arasındaki farklılık SKY ve sağlam bireyde anlamlı düzeyde değildi. Sonuç: QT dispersiyonu SKY hastalarda control grubuna gore daha yüksek idi. Bu durum bu hastalarda ventriküler aritmideki yüksek riske işaret edebilir, bununla beraber nörolojik yaralanma seviyesi, otonomik disfonskiyon ve yaralanmanın komplet olup olmaması bu riski arttırmaz.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Kronik spinal kord yaralı hastalarda otonomik disfonksiyonun QT dispersiyonu üzerine etkisi

Öz:

Objective: To provide data on patients with spinal cord injury (SCI) concerning the effect of autonomic dysfunction on QT dispersion as a predictor of ventricular arrhythmias, and to evaluate the risk of arrhythmia during both the resting state and urodynamic examination, which may increase the likelihood of autonomic dysreflexia due to bladder extension.Materials and Method: This prospective, case-controlled study included 30 patients with traumatic SCI and 27 healthy individuals. SCI patients and healthy controls underwent routine physical examination and 12-lead electrocardiography. In the patient group blood pressure and ECG records were obtained during urodynamic assessment. Measurement of the QT interval was performed manually by 2 blinded investigators. QT and QT corrected (QTc) dispersion were calculated. The SCI patients were compared according to the injury level and severity, and the existence of autonomic dysfunction based on urodynamic or autonomic examination.Results: QT and QTc dispersion values were higher in the SCI patients than in the controls. The difference in QT and QTc dispersion between the patients with and without autonomic dysfunction was not statistically significant. Conclusions: QT dispersion in the SCI patients was higher than that in the controls. As such, the risk of ventricular arrhythmia may be higher in such patients; however, neurological injury level, autonomic dysfunction, and completeness do not contribute to this risk.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Yasar E, YILMAZ B, YAŞAR A, kesikburun s, GÜZELKÜÇÜK Ü, Aydemir K, TEKİN L, GOKTEPE A, ALACA R, YAZICIOĞLU K, MÖHÜR H (2015). The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. , 5 - 10.
Chicago	Yasar Evren,YILMAZ Bilge,YAŞAR Ayşe Saatcı,kesikburun serdar,GÜZELKÜÇÜK Ümüt,Aydemir Koray,TEKİN Levent,GOKTEPE Ahmet Salim,ALACA RIDVAN,YAZICIOĞLU Kamil,MÖHÜR Haydar The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. (2015): 5 - 10.
MLA	Yasar Evren,YILMAZ Bilge,YAŞAR Ayşe Saatcı,kesikburun serdar,GÜZELKÜÇÜK Ümüt,Aydemir Koray,TEKİN Levent,GOKTEPE Ahmet Salim,ALACA RIDVAN,YAZICIOĞLU Kamil,MÖHÜR Haydar The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. , 2015, ss.5 - 10.
AMA	Yasar E,YILMAZ B,YAŞAR A,kesikburun s,GÜZELKÜÇÜK Ü,Aydemir K,TEKİN L,GOKTEPE A,ALACA R,YAZICIOĞLU K,MÖHÜR H The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. . 2015; 5 - 10.
Vancouver	Yasar E,YILMAZ B,YAŞAR A,kesikburun s,GÜZELKÜÇÜK Ü,Aydemir K,TEKİN L,GOKTEPE A,ALACA R,YAZICIOĞLU K,MÖHÜR H The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. . 2015; 5 - 10.
IEEE	Yasar E,YILMAZ B,YAŞAR A,kesikburun s,GÜZELKÜÇÜK Ü,Aydemir K,TEKİN L,GOKTEPE A,ALACA R,YAZICIOĞLU K,MÖHÜR H "The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury." , ss.5 - 10, 2015.
ISNAD	Yasar, Evren vd. "The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury". (2015), 5-10.

APA	Yasar E, YILMAZ B, YAŞAR A, kesikburun s, GÜZELKÜÇÜK Ü, Aydemir K, TEKİN L, GOKTEPE A, ALACA R, YAZICIOĞLU K, MÖHÜR H (2015). The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. Gülhane Tıp Dergisi, 57(1), 5 - 10.
Chicago	Yasar Evren,YILMAZ Bilge,YAŞAR Ayşe Saatcı,kesikburun serdar,GÜZELKÜÇÜK Ümüt,Aydemir Koray,TEKİN Levent,GOKTEPE Ahmet Salim,ALACA RIDVAN,YAZICIOĞLU Kamil,MÖHÜR Haydar The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. Gülhane Tıp Dergisi 57, no.1 (2015): 5 - 10.
MLA	Yasar Evren,YILMAZ Bilge,YAŞAR Ayşe Saatcı,kesikburun serdar,GÜZELKÜÇÜK Ümüt,Aydemir Koray,TEKİN Levent,GOKTEPE Ahmet Salim,ALACA RIDVAN,YAZICIOĞLU Kamil,MÖHÜR Haydar The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. Gülhane Tıp Dergisi, vol.57, no.1, 2015, ss.5 - 10.
AMA	Yasar E,YILMAZ B,YAŞAR A,kesikburun s,GÜZELKÜÇÜK Ü,Aydemir K,TEKİN L,GOKTEPE A,ALACA R,YAZICIOĞLU K,MÖHÜR H The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. Gülhane Tıp Dergisi. 2015; 57(1): 5 - 10.
Vancouver	Yasar E,YILMAZ B,YAŞAR A,kesikburun s,GÜZELKÜÇÜK Ü,Aydemir K,TEKİN L,GOKTEPE A,ALACA R,YAZICIOĞLU K,MÖHÜR H The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury. Gülhane Tıp Dergisi. 2015; 57(1): 5 - 10.
IEEE	Yasar E,YILMAZ B,YAŞAR A,kesikburun s,GÜZELKÜÇÜK Ü,Aydemir K,TEKİN L,GOKTEPE A,ALACA R,YAZICIOĞLU K,MÖHÜR H "The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury." Gülhane Tıp Dergisi, 57, ss.5 - 10, 2015.
ISNAD	Yasar, Evren vd. "The effect of autonomic dysfunction on QT dispersion in patients with chronic spinal cord injury". Gülhane Tıp Dergisi 57/1 (2015), 5-10.