Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with

cevikol, alev; eyigor, sibel; rezvani, aylin; ÇALISİ, Mustafa

Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with

Mustafa ÇALISİ, (Erciyes Üniversitesi, Tıp Fakültesi, Kayseri, Türkiye)

Aylin REZVANİ, (Bezmialem Vakıf Üniversitesi, Tıp Fakültesi, İstanbul, Türkiye)

Alev ÇEVİKOL, (Ankara Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Sibel EYİGÖR (Ege Üniversitesi, Tıp Fakültesi, İzmir, Türkiye)

Acta Orthopaedica et Traumatologica Turcica

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Yıl: 2016 Cilt: 50 Sayı: 4 Sayfa Aralığı: 415 - 423 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with

Öz:

Objective: In our study, we aimed to evaluate the influence of training on compliance and persistencewith bisphosphonate treatment given on a weekly vs. monthly basis in postmenopausal osteoporosispatients.Methods: A total of 979 patients with postmenopausal osteoporosis (mean age: 63.2± 7.2 years) wereincluded in this national, multicenter, prospective non-interventional observational cohort registrystudy. Patients were randomized into training (n¼ 492, 50.3%, mean age: 63.4 ± 7.2 years) and control(n¼ 487, 49.7%, mean age: 63.0 ± 7.1 years) groups. Patients in each intervention group were givenweekly (44.9% and 44.6% for training and control subjects, respectively) or monthly (55.1% and 55.4%,respectively) bisphosphonate regimens. After the initial visit, patients were followed up at three-monthintervals throughout 12 months of treatment for evaluation of persistence, compliance and adverseevents.Results: On average, 79.4% of the patients were persistent with the treatment with a mean of 350.4 daysof duration during the 12-month follow-up period. The mean compliance in the compliant and fullycompliant group remained at an average of 86.6%. No signiŞcant difference was detected between thetraining and control groups in terms of compliance and persistence. SigniŞcantly longer persistence(360.0± 89.0 vs. 345.0 ± 108.0 days; p ¼ 0.035), higher percentage of persistent patients (83.4% vs. 74.2%;p¼ 0.012) and higher compliance rates (88.8% vs. 83.3%; p ¼ 0.002) were noted in monthly regimenpatients in comparison to those given weekly regimen

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik

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APA	ÇALISİ M, rezvani a, cevikol a, eyigor s (2016). Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. , 415 - 423.
Chicago	ÇALISİ Mustafa,rezvani aylin,cevikol alev,eyigor sibel Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. (2016): 415 - 423.
MLA	ÇALISİ Mustafa,rezvani aylin,cevikol alev,eyigor sibel Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. , 2016, ss.415 - 423.
AMA	ÇALISİ M,rezvani a,cevikol a,eyigor s Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. . 2016; 415 - 423.
Vancouver	ÇALISİ M,rezvani a,cevikol a,eyigor s Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. . 2016; 415 - 423.
IEEE	ÇALISİ M,rezvani a,cevikol a,eyigor s "Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with." , ss.415 - 423, 2016.
ISNAD	ÇALISİ, Mustafa vd. "Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with". (2016), 415-423.

APA	ÇALISİ M, rezvani a, cevikol a, eyigor s (2016). Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. Acta Orthopaedica et Traumatologica Turcica, 50(4), 415 - 423.
Chicago	ÇALISİ Mustafa,rezvani aylin,cevikol alev,eyigor sibel Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. Acta Orthopaedica et Traumatologica Turcica 50, no.4 (2016): 415 - 423.
MLA	ÇALISİ Mustafa,rezvani aylin,cevikol alev,eyigor sibel Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. Acta Orthopaedica et Traumatologica Turcica, vol.50, no.4, 2016, ss.415 - 423.
AMA	ÇALISİ M,rezvani a,cevikol a,eyigor s Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. Acta Orthopaedica et Traumatologica Turcica. 2016; 50(4): 415 - 423.
Vancouver	ÇALISİ M,rezvani a,cevikol a,eyigor s Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with. Acta Orthopaedica et Traumatologica Turcica. 2016; 50(4): 415 - 423.
IEEE	ÇALISİ M,rezvani a,cevikol a,eyigor s "Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with." Acta Orthopaedica et Traumatologica Turcica, 50, ss.415 - 423, 2016.
ISNAD	ÇALISİ, Mustafa vd. "Influence of patient training on persistence, compliance, and tolerability of different dosing frequency regimens of bisphosphonate therapy: An observational study in Turkish patients with". Acta Orthopaedica et Traumatologica Turcica 50/4 (2016), 415-423.