Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas

Yıl: 2016 Cilt: 33 Sayı: 5 Sayfa Aralığı: 517 - 524 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas

Öz:
Background: Prognostic factors and the standard treatment approach for gynaecological carcinosarco-mas have not yet been clearly defined. Although car-cinosarcomas are more aggressive than pure epithelial tumours, they are treated similarly. Serous/clear cell and endometrioid components may be predictive fac-tors for the efficacy of adjuvant chemotherapy (CT) or radiotherapy (RT) or RT in patients with uterine and ovarian carcinosarcomas. Heterologous carcino-sarcomas may benefit more from adjuvant CT.Aims: We aimed to define the prognostic and predic-tive factors associated with treatment options in ovar-ian (OCS) and uterine carcinosarcoma (UCS).Study Design: Retrospective cross-sectional studyMethods: We retrospectively reviewed the medical re-cords of patients with ovarian and uterine carcinosar-coma from 2000 to 2013, and 127 women were includ-ed in this study (24 ovarian and 103 uterine). Patients admitted to seventeen oncology centres in Turkey be-tween 2000 and December 2013 with a histologically proven diagnosis of uterine carcinosarcoma with FIGO 2009 stage I-III and patients with sufficient data ob-tained from well-kept medical records were included in this study. Stage IV tumours were excluded. The pa-tient records were retrospectively reviewed. Data from 104 patients were evaluated for this study.Results: Age (>=70 years) was a poor prognostic factor for UCS (p=0.036). Pelvic±para aortic lymph node dis-section did not affect overall survival (OS) (p=0.35). Macroscopic residual disease was related with OS (p<0.01). The median OS was significantly longer in stage I-II patients than stage III patients (p=0.03). Adjuvant treatment improved OS (p=0.013). Adju-vant radiotherapy tended to increase the median OS
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APA Çiçin I, ÖZATLI T, TÜRKMEN E, Öztürk T, Özçelik M, Cabuk D, GÖKDURNALI A, BALVAN Ö, Yildiz Y, ŞEKER M, Ozdemir N, YAPAR B, Tanriverdi O, GÜNAYDIN Y, MENEKŞE S, ÖKSÜZOĞLU B, aksoy a, ERDOĞAN B, HACIOĞLU M, Arpaci E, SEVİNÇ A (2016). Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. , 517 - 524.
Chicago Çiçin Irfan,ÖZATLI TAHSİN,TÜRKMEN Esma,Öztürk Türkan,Özçelik Melike,Cabuk Devrim,GÖKDURNALI Ayşe,BALVAN Özlem,Yildiz Yasar,ŞEKER Metin,Ozdemir Nuriye,YAPAR Burcu,Tanriverdi Ozgur,GÜNAYDIN YUSUF,MENEKŞE Serkan,ÖKSÜZOĞLU Berna,aksoy asude,ERDOĞAN BÜLENT,HACIOĞLU M. Bekir,Arpaci Erkan,SEVİNÇ Alper Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. (2016): 517 - 524.
MLA Çiçin Irfan,ÖZATLI TAHSİN,TÜRKMEN Esma,Öztürk Türkan,Özçelik Melike,Cabuk Devrim,GÖKDURNALI Ayşe,BALVAN Özlem,Yildiz Yasar,ŞEKER Metin,Ozdemir Nuriye,YAPAR Burcu,Tanriverdi Ozgur,GÜNAYDIN YUSUF,MENEKŞE Serkan,ÖKSÜZOĞLU Berna,aksoy asude,ERDOĞAN BÜLENT,HACIOĞLU M. Bekir,Arpaci Erkan,SEVİNÇ Alper Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. , 2016, ss.517 - 524.
AMA Çiçin I,ÖZATLI T,TÜRKMEN E,Öztürk T,Özçelik M,Cabuk D,GÖKDURNALI A,BALVAN Ö,Yildiz Y,ŞEKER M,Ozdemir N,YAPAR B,Tanriverdi O,GÜNAYDIN Y,MENEKŞE S,ÖKSÜZOĞLU B,aksoy a,ERDOĞAN B,HACIOĞLU M,Arpaci E,SEVİNÇ A Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. . 2016; 517 - 524.
Vancouver Çiçin I,ÖZATLI T,TÜRKMEN E,Öztürk T,Özçelik M,Cabuk D,GÖKDURNALI A,BALVAN Ö,Yildiz Y,ŞEKER M,Ozdemir N,YAPAR B,Tanriverdi O,GÜNAYDIN Y,MENEKŞE S,ÖKSÜZOĞLU B,aksoy a,ERDOĞAN B,HACIOĞLU M,Arpaci E,SEVİNÇ A Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. . 2016; 517 - 524.
IEEE Çiçin I,ÖZATLI T,TÜRKMEN E,Öztürk T,Özçelik M,Cabuk D,GÖKDURNALI A,BALVAN Ö,Yildiz Y,ŞEKER M,Ozdemir N,YAPAR B,Tanriverdi O,GÜNAYDIN Y,MENEKŞE S,ÖKSÜZOĞLU B,aksoy a,ERDOĞAN B,HACIOĞLU M,Arpaci E,SEVİNÇ A "Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas." , ss.517 - 524, 2016.
ISNAD Çiçin, Irfan vd. "Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas". (2016), 517-524.
APA Çiçin I, ÖZATLI T, TÜRKMEN E, Öztürk T, Özçelik M, Cabuk D, GÖKDURNALI A, BALVAN Ö, Yildiz Y, ŞEKER M, Ozdemir N, YAPAR B, Tanriverdi O, GÜNAYDIN Y, MENEKŞE S, ÖKSÜZOĞLU B, aksoy a, ERDOĞAN B, HACIOĞLU M, Arpaci E, SEVİNÇ A (2016). Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. Balkan Medical Journal, 33(5), 517 - 524.
Chicago Çiçin Irfan,ÖZATLI TAHSİN,TÜRKMEN Esma,Öztürk Türkan,Özçelik Melike,Cabuk Devrim,GÖKDURNALI Ayşe,BALVAN Özlem,Yildiz Yasar,ŞEKER Metin,Ozdemir Nuriye,YAPAR Burcu,Tanriverdi Ozgur,GÜNAYDIN YUSUF,MENEKŞE Serkan,ÖKSÜZOĞLU Berna,aksoy asude,ERDOĞAN BÜLENT,HACIOĞLU M. Bekir,Arpaci Erkan,SEVİNÇ Alper Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. Balkan Medical Journal 33, no.5 (2016): 517 - 524.
MLA Çiçin Irfan,ÖZATLI TAHSİN,TÜRKMEN Esma,Öztürk Türkan,Özçelik Melike,Cabuk Devrim,GÖKDURNALI Ayşe,BALVAN Özlem,Yildiz Yasar,ŞEKER Metin,Ozdemir Nuriye,YAPAR Burcu,Tanriverdi Ozgur,GÜNAYDIN YUSUF,MENEKŞE Serkan,ÖKSÜZOĞLU Berna,aksoy asude,ERDOĞAN BÜLENT,HACIOĞLU M. Bekir,Arpaci Erkan,SEVİNÇ Alper Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. Balkan Medical Journal, vol.33, no.5, 2016, ss.517 - 524.
AMA Çiçin I,ÖZATLI T,TÜRKMEN E,Öztürk T,Özçelik M,Cabuk D,GÖKDURNALI A,BALVAN Ö,Yildiz Y,ŞEKER M,Ozdemir N,YAPAR B,Tanriverdi O,GÜNAYDIN Y,MENEKŞE S,ÖKSÜZOĞLU B,aksoy a,ERDOĞAN B,HACIOĞLU M,Arpaci E,SEVİNÇ A Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. Balkan Medical Journal. 2016; 33(5): 517 - 524.
Vancouver Çiçin I,ÖZATLI T,TÜRKMEN E,Öztürk T,Özçelik M,Cabuk D,GÖKDURNALI A,BALVAN Ö,Yildiz Y,ŞEKER M,Ozdemir N,YAPAR B,Tanriverdi O,GÜNAYDIN Y,MENEKŞE S,ÖKSÜZOĞLU B,aksoy a,ERDOĞAN B,HACIOĞLU M,Arpaci E,SEVİNÇ A Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas. Balkan Medical Journal. 2016; 33(5): 517 - 524.
IEEE Çiçin I,ÖZATLI T,TÜRKMEN E,Öztürk T,Özçelik M,Cabuk D,GÖKDURNALI A,BALVAN Ö,Yildiz Y,ŞEKER M,Ozdemir N,YAPAR B,Tanriverdi O,GÜNAYDIN Y,MENEKŞE S,ÖKSÜZOĞLU B,aksoy a,ERDOĞAN B,HACIOĞLU M,Arpaci E,SEVİNÇ A "Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas." Balkan Medical Journal, 33, ss.517 - 524, 2016.
ISNAD Çiçin, Irfan vd. "Predictive and Prognostic Factors in Ovarian and Uterine Carcinosarcomas". Balkan Medical Journal 33/5 (2016), 517-524.