The relationship between blood lactate levels and mortality in pediatric intensive care patients

YEL, Servet; KELEKÇİ, Selvi; YOLBAŞ, İlyas; ŞEN, velat; GÜNEŞ, Ali; BOŞNAK, Mehmet

The relationship between blood lactate levels and mortality in pediatric intensive care patients

İlyas YOLBAŞ, (Dicle Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Diyarbakır, Türkiye)

Velat ŞEN, (Dicle Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Diyarbakır, Türkiye)

Mehmet BOŞNAK, (Gaziantep Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Gaziantep, Türkiye)

Selvi KELEKÇİ, (Dicle Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Diyarbakır, Türkiye)

Servet YEL, (Dicle Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Diyarbakır, Türkiye)

Ali GÜNEŞ (Dicle Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Diyarbakır, Türkiye)

Journal of Clinical and Experimental Investigations

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Yıl: 2013 Cilt: 4 Sayı: 3 Sayfa Aralığı: 269 - 273 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The relationship between blood lactate levels and mortality in pediatric intensive care patients

Öz:

Amaç: Çocuk yoğun bakım servisinde takip edilen kritik hasta çocuklardaki kan laktat düzeyi ile mortalite arasındaki ilişkiyi belirlemekYöntemler: Ocak 2007 ve Aralık 2007 tarihleri arasında Dicle Üniversitesi Tıp Fakültesi, üçüncü basamak Çocuk Yoğun Bakım Ünitesinde takip edilmiş, kritik hasta 28 günden büyük ve 16 yaşından küçük çocuklar seçildi. Hastaların yaşı, cinsiyeti, tanısı, Glasgow koma skorlaması puanı, ilk ölçülmüş kan laktat düzeyi (laktat 1) ve tedavi sırasında tüm ölçülmüş kan laktat düzeylerinin aritmetik ortalaması (laktat 2) verileri retrospektif olarak değerlendirildi. Hastalar; grup A (laktat <=19 mg/dl) ve grup B (laktat >=20mg/dl) olarak iki gruba ayrıldı. Sonlanıma göre, hastalar yaşayanlar ve ölenler olarak iki gruba ayırıldı. Bu grupların mortalite oranları ve laktat düzeylerini karşılaştırıldı. Bulgular: Çalışmada; 140'ı yaşamış ve 158'i ölmüş olan toplam 298 vaka değerlendirildi. Laktat 1 ve laktat 2 seviyeleri ile mortalite arasında anlamlı bir ilişki bulundu. Ölen hastalarda laktat düzeyi anlamlı olarak daha yüksekti (p<0.001). Grup B'de laktat 1 değerinin mortalite riskini belirlemedeki sensitivitesi % 68 (106/156), spesifitesi %75 (106/142) iken, laktat 2 değerinin mortalite riskini belirlemedeki sensitivitesi %85 (134/158), spesifitesi % 79 (134/169) idi.Sonuç: Çocuk yoğun bakım servisinde takip edilen kritik hastalarda, kan laktat yüksekliği ile mortalite arasında kuvvetli bir ilişki vardır. Bu hastalarda takip ve tedavinin etkinliğini değerlendirmede ve mortaliteyi belirlemede kan laktat seviyesi kullanılabilir

Anahtar Kelime:

Konular: Anestezi Yoğun Bakım, Tıp

Çocuk yoğun bakım hastalarında kan laktat düzeyleri ile mortalite arasındaki ilişki

Öz:

Objective: To determine relationship between blood lactate level and mortality rate in children admitted to the intensive care unit.Methods: 298 critically ill patients aged between 28 days and 16 years admitted to Dicle University Hospital, the third step Pediatric Intensive Care Unit in between January 2007 and December 2007 were included. Age, sex, diagnosis, Glasgow coma score points, the first measured blood lactate levels (lactate 1) and the arithmetic average of all measured blood lactate levels during treatment (lactate 2) of cases were evaluated. Patients were divided into group A (lactate < 20 mg/dl) and B (lactate >= 20 mg/dl). According to the results, patients were classified as survivors and non-survivors. Both lactate 1 and lactate 2 were compared with mortality rates.Results: In this study, a total of 298 patients were evaluated, 158 of them were nonsurvivors and 140 were survivors. A significant correlation was found between lactate levels and mortality rates. Lactate levels were higher in non-survivor cases (p<0.001). In group B, lactate 1 had 68% (106/156) sensitivity and 75% (106/142) specificity for determining the risk of mortality. Also in group B, lactate 2 had 85% (134/158) sensitivity and 79% (134/169) specificity for determining the risk of mortality.Conclusion: There is a strong association between high blood lactate levels and mortality rates in the critically ill patients in pediatric intensive care unit. In these patients blood lactate levels can be used for follow-up and evaluation of the effectiveness of treatment and determining mortality. J Clin Exp Invest 2013; 4 (3): 269-273

Anahtar Kelime:

Konular: Anestezi Yoğun Bakım, Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	YOLBAŞ İ, ŞEN v, BOŞNAK M, KELEKÇİ S, YEL S, GÜNEŞ A (2013). The relationship between blood lactate levels and mortality in pediatric intensive care patients. , 269 - 273.
Chicago	YOLBAŞ İlyas,ŞEN velat,BOŞNAK Mehmet,KELEKÇİ Selvi,YEL Servet,GÜNEŞ Ali The relationship between blood lactate levels and mortality in pediatric intensive care patients. (2013): 269 - 273.
MLA	YOLBAŞ İlyas,ŞEN velat,BOŞNAK Mehmet,KELEKÇİ Selvi,YEL Servet,GÜNEŞ Ali The relationship between blood lactate levels and mortality in pediatric intensive care patients. , 2013, ss.269 - 273.
AMA	YOLBAŞ İ,ŞEN v,BOŞNAK M,KELEKÇİ S,YEL S,GÜNEŞ A The relationship between blood lactate levels and mortality in pediatric intensive care patients. . 2013; 269 - 273.
Vancouver	YOLBAŞ İ,ŞEN v,BOŞNAK M,KELEKÇİ S,YEL S,GÜNEŞ A The relationship between blood lactate levels and mortality in pediatric intensive care patients. . 2013; 269 - 273.
IEEE	YOLBAŞ İ,ŞEN v,BOŞNAK M,KELEKÇİ S,YEL S,GÜNEŞ A "The relationship between blood lactate levels and mortality in pediatric intensive care patients." , ss.269 - 273, 2013.
ISNAD	YOLBAŞ, İlyas vd. "The relationship between blood lactate levels and mortality in pediatric intensive care patients". (2013), 269-273.

APA	YOLBAŞ İ, ŞEN v, BOŞNAK M, KELEKÇİ S, YEL S, GÜNEŞ A (2013). The relationship between blood lactate levels and mortality in pediatric intensive care patients. Journal of Clinical and Experimental Investigations, 4(3), 269 - 273.
Chicago	YOLBAŞ İlyas,ŞEN velat,BOŞNAK Mehmet,KELEKÇİ Selvi,YEL Servet,GÜNEŞ Ali The relationship between blood lactate levels and mortality in pediatric intensive care patients. Journal of Clinical and Experimental Investigations 4, no.3 (2013): 269 - 273.
MLA	YOLBAŞ İlyas,ŞEN velat,BOŞNAK Mehmet,KELEKÇİ Selvi,YEL Servet,GÜNEŞ Ali The relationship between blood lactate levels and mortality in pediatric intensive care patients. Journal of Clinical and Experimental Investigations, vol.4, no.3, 2013, ss.269 - 273.
AMA	YOLBAŞ İ,ŞEN v,BOŞNAK M,KELEKÇİ S,YEL S,GÜNEŞ A The relationship between blood lactate levels and mortality in pediatric intensive care patients. Journal of Clinical and Experimental Investigations. 2013; 4(3): 269 - 273.
Vancouver	YOLBAŞ İ,ŞEN v,BOŞNAK M,KELEKÇİ S,YEL S,GÜNEŞ A The relationship between blood lactate levels and mortality in pediatric intensive care patients. Journal of Clinical and Experimental Investigations. 2013; 4(3): 269 - 273.
IEEE	YOLBAŞ İ,ŞEN v,BOŞNAK M,KELEKÇİ S,YEL S,GÜNEŞ A "The relationship between blood lactate levels and mortality in pediatric intensive care patients." Journal of Clinical and Experimental Investigations, 4, ss.269 - 273, 2013.
ISNAD	YOLBAŞ, İlyas vd. "The relationship between blood lactate levels and mortality in pediatric intensive care patients". Journal of Clinical and Experimental Investigations 4/3 (2013), 269-273.