Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis

Ortac, Emine Aygul; COŞKUN BENLİDAYI, İLKE; KOZANOĞLU, MUSTAFA ERKAN

Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis

İlke COŞKUN BENLİDAYI, (Çukurova Üniversitesi, Tıp Fakültesi, Fizik Tıp ve Rehabilitasyon Anabilim Dalı, Adana, Türkiye)

MUSTAFA ERKAN KOZANOĞLU, (Çukurova Üniversitesi, Tıp Fakültesi, Fizik Tıp ve Rehabilitasyon Anabilim Dalı, Adana, Türkiye)

Emine Aygül ORTAÇ (Çukurova Üniversitesi, Tıp Fakültesi, Fizik Tıp ve Rehabilitasyon Anabilim Dalı, Adana, Türkiye)

Çukurova Üniversitesi Tıp Fakültesi Dergisi

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Yıl: 2015 Cilt: 40 Sayı: 4 Sayfa Aralığı: 818 - 821 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis

Öz:

Ülseratif kolit, periferik ve aksiyel artropatiler gibi ekstraintestinal bulguların eşlik ettiği progresif bir inflamatuvar barsak hastalığıdır. Ülseratif kolitli hastalarda bazen romatoid artritten ayırt edilmesi zor olan romatoid paternli poliartropati görülebilmektedir. Bu yazıda, ülseratif koliti komplike eden romatoid paternli bir poliartropati vakası ve infliximab tedavisine verdiği olumlu yanıt sunulmaktadır. Ülseratif kolit tanısı almış 25 yaşında bir kadın hasta çeşitli eklemlerinde şişlik ve ağrı yakınmasıyla başvurdu. Laboratuar testlerinde akut faz reaktanları yüksekti. Metotreksat, sulfasalazin ve steroid kombinasyonuna yanıtsız olması nedeniyle hastaya infliximab tedavisi başlandı. Ağrı skorları ve biyokimyasal belirteçlerde düzelme gözlendi. Altı aylık anti-tümör nekrozis faktör (anti-TNF) tedavisi sonunda akut faz reaktanları düştü ve hasta asemptomatikti. Infliximab, ülseratif kolitle ilişkili romatoid paternli periferik poliartritte kullanılabilecek etkin bir tedavi seçeneğidir

Anahtar Kelime:

Konular: Cerrahi

Ülseratif Koliti Komplike Eden Romatoid Paternli Poliartropatide Kısa Dönem Infliximab Yanıtı

Öz:

Ulcerative colitis (UC) is a progressive inflammatory disease (IBD) of the bowel which can be accompanied by extraintestinal findings such as peripheral and axial arthropathies. Patients with UC sometimes display rheumatoid pattern polyarthropathy which is challenging to differ from rheumatoid arthritis. We describe a case with rheumatoid pattern polyarthropathy complicating UC and her favourable response to infliximab therapy. A 25-year-old female with a diagnosis of UC was admitted due to swelling and pain in multiple joints. Laboratory tests revealed elevated acute phase reactants. Since the patient was refractory to the combination therapy comprising methotrexate, sulphasalazine and steroid, she was started on an infliximab regimen. She experienced an improvement both in terms of pain scores and biochemical findings. The patient was asymptomatic with reduced acute phase reactants following a 6-monthcourse of anti-tumor necrosis factor (anti-TNF) therapy. Infliximab serves as an effective treatment option for the management of rheumatoid pattern peripheral polyarthritis associated with UC

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

Andrisani G, Guidi L, Papa A, Armuzzi A. Anti-TNF alpha therapy in the management of extraintestinal manifestation of inflammatory bowel disease. Eur Rev Med Pharmacol Sci. 2012;16:890-901.
D'Incà R, Podswiadek M, Ferronato A, Punzi L, Salvagnini M, Sturniolo GC. Articular manifestations in inflammatory bowel disease patients: a prospective study. Dig Liver Dis 2009;41:11565-9.
Orchard TR, Orchard TR, Wordsworth BP, Jewell DP. Peripheral arthropathies in inflammatory bowel disease: their articular distribution and natural history. Gut. 1998;42:387-91.
Dorofeyev AE, Vasilenko IV, Rassokhina OA. Joint extraintestinal manifestations in ulcerative colitis. Dig Dis 2009;27: 502-10.
Boyer F, Fontanges E, Miossec P. Rheumatoid arthritis associated with ulcerative colitis: a case with severe flare of both diseases after delivery. Ann Rheum Dis. 2001;60:901. Ulker A, et al. Peripheral arthritis in the course of inflammatory bowel diseases. Dig Dis Sci. 2011;56:183-7.
Orchard TR, Thiyagaraja S, Welsh KI, Wordsworth BP, Hill Gaston JS, Jewell DP. Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease. Gastroenterology. 2000;118:274-8.
Cruz VA, Yamaguchi L, Ribeiro CN, Magalhães Vde O, Rego J, Silva NA. Ulcerative colitis and rheumatoid arthritis: a rare association--case report. Rev Bras Reumatol. 2012;52:648-50.
Lesuis N, Befrits R, Nyberg F, van Vollenhoven RF. Gender and the treatment of immune-mediated chronic inflammatory diseases: rheumatoid arthritis, inflammatory bowel disease and psoriasis: an observational study. BMC Med. 2012;10:82.
Kollias G, Douni E, Kassiotis G, Kontoyiannis D. On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Immunol Rev. 1999;169:175-94.

APA	COŞKUN BENLİDAYI İ, KOZANOĞLU M, Ortac E (2015). Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. , 818 - 821.
Chicago	COŞKUN BENLİDAYI İLKE,KOZANOĞLU MUSTAFA ERKAN,Ortac Emine Aygul Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. (2015): 818 - 821.
MLA	COŞKUN BENLİDAYI İLKE,KOZANOĞLU MUSTAFA ERKAN,Ortac Emine Aygul Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. , 2015, ss.818 - 821.
AMA	COŞKUN BENLİDAYI İ,KOZANOĞLU M,Ortac E Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. . 2015; 818 - 821.
Vancouver	COŞKUN BENLİDAYI İ,KOZANOĞLU M,Ortac E Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. . 2015; 818 - 821.
IEEE	COŞKUN BENLİDAYI İ,KOZANOĞLU M,Ortac E "Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis." , ss.818 - 821, 2015.
ISNAD	COŞKUN BENLİDAYI, İLKE vd. "Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis". (2015), 818-821.

APA	COŞKUN BENLİDAYI İ, KOZANOĞLU M, Ortac E (2015). Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. Çukurova Üniversitesi Tıp Fakültesi Dergisi, 40(4), 818 - 821.
Chicago	COŞKUN BENLİDAYI İLKE,KOZANOĞLU MUSTAFA ERKAN,Ortac Emine Aygul Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. Çukurova Üniversitesi Tıp Fakültesi Dergisi 40, no.4 (2015): 818 - 821.
MLA	COŞKUN BENLİDAYI İLKE,KOZANOĞLU MUSTAFA ERKAN,Ortac Emine Aygul Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. Çukurova Üniversitesi Tıp Fakültesi Dergisi, vol.40, no.4, 2015, ss.818 - 821.
AMA	COŞKUN BENLİDAYI İ,KOZANOĞLU M,Ortac E Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. Çukurova Üniversitesi Tıp Fakültesi Dergisi. 2015; 40(4): 818 - 821.
Vancouver	COŞKUN BENLİDAYI İ,KOZANOĞLU M,Ortac E Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis. Çukurova Üniversitesi Tıp Fakültesi Dergisi. 2015; 40(4): 818 - 821.
IEEE	COŞKUN BENLİDAYI İ,KOZANOĞLU M,Ortac E "Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis." Çukurova Üniversitesi Tıp Fakültesi Dergisi, 40, ss.818 - 821, 2015.
ISNAD	COŞKUN BENLİDAYI, İLKE vd. "Short-Term Response to Infliximab in Rheumatoid Pattern Polyarthropathy Complicating Ulcerative Colitis". Çukurova Üniversitesi Tıp Fakültesi Dergisi 40/4 (2015), 818-821.