Yıl: 2015 Cilt: 39 Sayı: 1 Sayfa Aralığı: 23 - 30 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Cytotoxic effects of various lactic acid bacteria on Caco-2 cells

Öz:
Probiotics are live microbial food supplements that can be considered a functional food. They benefit the health of a host animal by maintaining their intestinal microbial balance. Most probiotic microorganisms are lactic acid bacteria (LAB) such as Lactobacillus spp., Bifidobacterium spp., and Enterococcus spp. LAB have been reported to possess certain anticancer properties. The vast majority of studies on their anticancer effects have dealt with colorectal cancers, although there have also been some studies on breast and bladder cancers. Colon cancer is the fourth most common cause of cancer-related mortality in the world. The aim of this study was to investigate the antiproliferative effects of the cell-free filtrate and the cell-free lyophilized filtrate of 3 LAB (Pediococcus pentosaceus, Lactobacillus plantarum, and Weissella confusa) on human colorectal adenocarcinoma cell line Caco-2. The filtrates were found to inhibit the growth of colon cancer cells in a dose-dependent manner as detected by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, suggesting that these strains might have use as probiotics in functional food or for colon cancer treatment. There are no other studies related to the anticancer activities of W. confusa in the literature.
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Konular: Biyoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ER S, Koparal A, KIVANÇ M (2015). Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. , 23 - 30.
Chicago ER Sevda,Koparal Ayse,KIVANÇ Merih Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. (2015): 23 - 30.
MLA ER Sevda,Koparal Ayse,KIVANÇ Merih Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. , 2015, ss.23 - 30.
AMA ER S,Koparal A,KIVANÇ M Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. . 2015; 23 - 30.
Vancouver ER S,Koparal A,KIVANÇ M Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. . 2015; 23 - 30.
IEEE ER S,Koparal A,KIVANÇ M "Cytotoxic effects of various lactic acid bacteria on Caco-2 cells." , ss.23 - 30, 2015.
ISNAD ER, Sevda vd. "Cytotoxic effects of various lactic acid bacteria on Caco-2 cells". (2015), 23-30.
APA ER S, Koparal A, KIVANÇ M (2015). Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. Turkish Journal of Biology, 39(1), 23 - 30.
Chicago ER Sevda,Koparal Ayse,KIVANÇ Merih Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. Turkish Journal of Biology 39, no.1 (2015): 23 - 30.
MLA ER Sevda,Koparal Ayse,KIVANÇ Merih Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. Turkish Journal of Biology, vol.39, no.1, 2015, ss.23 - 30.
AMA ER S,Koparal A,KIVANÇ M Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. Turkish Journal of Biology. 2015; 39(1): 23 - 30.
Vancouver ER S,Koparal A,KIVANÇ M Cytotoxic effects of various lactic acid bacteria on Caco-2 cells. Turkish Journal of Biology. 2015; 39(1): 23 - 30.
IEEE ER S,Koparal A,KIVANÇ M "Cytotoxic effects of various lactic acid bacteria on Caco-2 cells." Turkish Journal of Biology, 39, ss.23 - 30, 2015.
ISNAD ER, Sevda vd. "Cytotoxic effects of various lactic acid bacteria on Caco-2 cells". Turkish Journal of Biology 39/1 (2015), 23-30.