Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies

CEYHAN, Koray; Atasoy, Cetin; Gulpinar, Basak; Uzun, Çağlar; PEKER, Elif; Üstüner, Evren; ELHAN, Atilla Halil; TICLE, ORIGINAL AR; DÜŞÜNCELİ ATMAN, EBRU; Akkaya, Zehra

Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies

Çağlar UZUN, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Zehra AKKAYA, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Ebru DÜŞÜNCELİ ATMAN, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Evren ÜSTÜNER, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Elif PEKER, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Başak GÜLPINAR, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Atilla Halil ELHAN, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Koray CEYHAN, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Kayhan Çetin ATASOY, (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

ORIGINAL AR TICLE (Ankara Üniversitesi, Tıp Fakültesi, Ankara, Türkiye)

Diagnostic and Interventional Radiology

2 0

Yıl: 2017 Cilt: 23 Sayı: 2 Sayfa Aralığı: 137 - 143 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies

Öz:

PURPOSE We aimed to evaluate the diagnostic accuracy and safety of computed tomography (CT)-guided biopsy of pulmonary lesions with fine needle aspiration (FNA) using non-coaxial technique.METHODSWe analyzed 442 patients who underwent CT-guided lung biopsy with FNA and non-coaxial technique to determine the diagnostic outcomes, complication rates, and independent risk fac-tors for diagnostic failure and pneumothorax.RESULTSDiagnostic accuracy, sensitivity, and specificity were 97.6%, 97.3%, and 100%, respectively. Age and >35 mm lesion size were significant risk factors for diagnostic failure. The rates of pneu-mothorax and chest tube placement were 19% and 2.9%, respectively. Middle and lower lobe location, lesion to pleura distance >7.5 mm, and >45° needle trajectory angle were significant risk factors for pneumothorax.CONCLUSIONCT-guided FNA of pulmonary lesions with non-coaxial technique is a safe and reliable method with a relatively low pneumothorax rate and an acceptably high diagnostic accuracy.

Anahtar Kelime:

Konular: Radyoloji, Nükleer Tıp, Tıbbi Görüntüleme

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

Tsukada H, Satou T, Iwashima A, Souma T. Diag- nostic accuracy of CT-guided automated nee- dle biopsy of lung nodules. AJR Am J Roentge- nol 2000; 175:239-243. [CrossRef]
Hiraki T, Mimura H, Gobara H, et al. CT fluoros- copy-guided biopsy of 1,000 pulmonary le- sions performed with 20-gauge coaxial cutting needles: diagnostic yield and risk factors for diagnostic failure. Chest 2009; 136:1612-1617. [CrossRef]
Arakawa H, Nakajima Y, Kurihara Y, Niimi H, Ishi- kawa T. CT-guided transthoracic needle biopsy: a comparison between automated biopsy gun and fine needle aspiration. Clin Radiol 1996; 51:503-506. [CrossRef]
Takeshita J, Masago K, Kato R, et al. CT-guided fine-needle aspiration and core needle biop- sies of pulmonary lesions: a single-center ex- perience with 750 biopsies in Japan. AJR Am J Roentgenol 2015; 204:29-34. [CrossRef]
Yeow KM, Tsay PK, Cheung YC, Lui KW, Pan KT, Chou AS. Factors affecting diagnostic accuracy of CT-guided coaxial cutting needle lung biopsy: retrospective analysis of 631 procedures. J Vasc Interv Radiol 2003; 14:581-588. [CrossRef]
Khan MF, Straub R, Moghaddam SR, et al. Vari- ables affecting the risk of pneumothorax and intrapulmonal hemorrhage in CT-guided trans- thoracic biopsy. Eur Radiol 2008; 18:1356-1363. [CrossRef]
Covey AM, Gandhi R, Brody LA, Getrajdman G, Thaler HT, Brown KT. Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients. J Vasc Interv Radiol 2004; 15:479-483. [CrossRef]
Kuban JD, Tam AL, Huang SY, et al. The effect of needle gauge on the risk of pneumotho- rax and chest tube placement after percuta- neous computed tomographic (CT)-guided lung biopsy. Cardiovasc Intervent Radiol 2015; 38:1595-1602. [CrossRef]
Geraghty PR, Kee ST, McFarlane G, Razavi MK, Sze DY, Dake MD. CT-guided transthoracic nee- dle aspiration biopsy of pulmonary nodules: needle size and pneumothorax rate. Radiology 2003; 229:475-481. [CrossRef]
Priola AM, Priola SM, Cataldi A, et al. Diagnostic accuracy and complication rate of CT-guided fine needle aspiration biopsy of lung lesions: a study based on the experience of the cytopathologist. Acta Radiol 2010; 51:527-533. [CrossRef]
Mullan CP, Kelly BE, Ellis PK, Hughes S, Anderson N, McCluggage WG. CT- guided fine-needle as- piration of lung nodules: effect on outcome of using coaxial technique and immediate cyto- logical evaluation. Ulster med J 2004; 73:32-36.
Hanley, J.A. and McNeil, B.J. The meaning and use of the area under a receiver operating charac- teristic (ROC) curve. Radiology 1983; 143:29-36. [CrossRef]
Wilber ST, Fu R. Risk ratios and odds ratios for common events in cross-sectional and cohort studies. Acad Emerg Med 2010; 17:649-651. [CrossRef]
Laurent F, Latrabe V, Vergier B, Michel P. Percuta- neous CT-guided biopsy of the lung: comparison between aspiration and automated cutting nee- dles using a coaxial technique. Cardiovasc Inter- vent Radiol 2000; 23:266-272. [CrossRef]
Montaudon M, Latrabe V, Pariente A, Corneloup O, Bequeret H, Laurent F. Factors influencing accu- racy of CT-guided percutaneous biopsies of pul- monary lesions. Eur Radiol 2004; 14:1234-1240. [CrossRef]
Klein JS, Salomon G, Stewart EA. Transthoracic needle biopsy with a coaxially placed 20-gauge automated cutting needle: results in 122 pa- tients. Radiology 1996; 198:715-720. [CrossRef]
Boiselle PM, Shepard JA, Mark EJ, et al. Routine addition of an automated biopsy device to fine-needle aspiration of the lung: a prospec- tive assessment. AJR Am J Roentgenol 1997; 169:661-666. [CrossRef]
Ohno Y, Hatabu H, Takenaka D, et al. CT-guided transthoracic needle aspiration biopsy of small (_____ or = 20 mm) solitary pulmonary nodules. AJR Am J Roentgenol 2003; 180:1665-1669. [CrossRef]
Cox JE, Chiles C, McManus CM, Aquino SL, Choplin RH. Transthoracic needle aspiration bi- opsy: variables that affect risk of pneumotho- rax. Radiology 1999; 212:165-168. [CrossRef]
Ko JP, Shepard JO, Drucker EA, et al. Factors influencing pneumothorax rate at lung biop- sy: are dwell time and angle of pleural punc- ture contributing factors? Radiology 2001; 218:491-496. [CrossRef]
Nour-Eldin NA, Alsubhi M, Emam A, et al. Pneu- mothorax complicating coaxial and non-coaxi- al CT-guided lung biopsy: comparative analysis of determining risk factors and management of pneumothorax in a retrospective review of 650 patients. Cardiovasc Intervent Radiol 2016; 39:261-270. [CrossRef]
Hiraki T, Mimura H, Gobara H, et al. Incidence of and risk factors for pneumothorax and chest tube placement after CT fluoroscopy-guided percutaneous lung biopsy: retrospective anal- ysis of the procedures conducted over a 9-year period. AJR Am J Roentgenol 2010; 194:809- 814. [CrossRef]
Saji H, Nakamura H, Tsuchida T, et al. The inci- dence and the risk of pneumothorax and chest tube placement after percutaneous CT-guided lung biopsy: the angle of the needle trajecto- ry is a novel predictor. Chest 2002; 121:1521- 1526. [CrossRef]
Laurent F, Michel P, Latrabe V, Tunon de Lara M, Marthan R. Pneumothoraces and chest tube placement after CT-guided transthoracic lung biopsy using a coaxial technique: incidence and risk factors. AJR Am J Roentgenol 1999; 172:1049-1053. [CrossRef]
Yeow KM, Su IH, Pan KT, et al. Risk factors of pneumothorax and bleeding: multivariate analysis of 660 CT-guided coaxial cutting nee- dle lung biopsies. Chest 2004; 126:748-754. [CrossRef]

APA	Uzun Ç, Akkaya Z, DÜŞÜNCELİ ATMAN E, Üstüner E, PEKER E, Gulpinar B, ELHAN A, CEYHAN K, Atasoy C, TICLE O (2017). Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. , 137 - 143.
Chicago	Uzun Çağlar,Akkaya Zehra,DÜŞÜNCELİ ATMAN EBRU,Üstüner Evren,PEKER Elif,Gulpinar Basak,ELHAN Atilla Halil,CEYHAN Koray,Atasoy Cetin,TICLE ORIGINAL AR Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. (2017): 137 - 143.
MLA	Uzun Çağlar,Akkaya Zehra,DÜŞÜNCELİ ATMAN EBRU,Üstüner Evren,PEKER Elif,Gulpinar Basak,ELHAN Atilla Halil,CEYHAN Koray,Atasoy Cetin,TICLE ORIGINAL AR Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. , 2017, ss.137 - 143.
AMA	Uzun Ç,Akkaya Z,DÜŞÜNCELİ ATMAN E,Üstüner E,PEKER E,Gulpinar B,ELHAN A,CEYHAN K,Atasoy C,TICLE O Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. . 2017; 137 - 143.
Vancouver	Uzun Ç,Akkaya Z,DÜŞÜNCELİ ATMAN E,Üstüner E,PEKER E,Gulpinar B,ELHAN A,CEYHAN K,Atasoy C,TICLE O Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. . 2017; 137 - 143.
IEEE	Uzun Ç,Akkaya Z,DÜŞÜNCELİ ATMAN E,Üstüner E,PEKER E,Gulpinar B,ELHAN A,CEYHAN K,Atasoy C,TICLE O "Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies." , ss.137 - 143, 2017.
ISNAD	Uzun, Çağlar vd. "Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies". (2017), 137-143.

APA	Uzun Ç, Akkaya Z, DÜŞÜNCELİ ATMAN E, Üstüner E, PEKER E, Gulpinar B, ELHAN A, CEYHAN K, Atasoy C, TICLE O (2017). Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. Diagnostic and Interventional Radiology, 23(2), 137 - 143.
Chicago	Uzun Çağlar,Akkaya Zehra,DÜŞÜNCELİ ATMAN EBRU,Üstüner Evren,PEKER Elif,Gulpinar Basak,ELHAN Atilla Halil,CEYHAN Koray,Atasoy Cetin,TICLE ORIGINAL AR Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. Diagnostic and Interventional Radiology 23, no.2 (2017): 137 - 143.
MLA	Uzun Çağlar,Akkaya Zehra,DÜŞÜNCELİ ATMAN EBRU,Üstüner Evren,PEKER Elif,Gulpinar Basak,ELHAN Atilla Halil,CEYHAN Koray,Atasoy Cetin,TICLE ORIGINAL AR Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. Diagnostic and Interventional Radiology, vol.23, no.2, 2017, ss.137 - 143.
AMA	Uzun Ç,Akkaya Z,DÜŞÜNCELİ ATMAN E,Üstüner E,PEKER E,Gulpinar B,ELHAN A,CEYHAN K,Atasoy C,TICLE O Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. Diagnostic and Interventional Radiology. 2017; 23(2): 137 - 143.
Vancouver	Uzun Ç,Akkaya Z,DÜŞÜNCELİ ATMAN E,Üstüner E,PEKER E,Gulpinar B,ELHAN A,CEYHAN K,Atasoy C,TICLE O Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies. Diagnostic and Interventional Radiology. 2017; 23(2): 137 - 143.
IEEE	Uzun Ç,Akkaya Z,DÜŞÜNCELİ ATMAN E,Üstüner E,PEKER E,Gulpinar B,ELHAN A,CEYHAN K,Atasoy C,TICLE O "Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies." Diagnostic and Interventional Radiology, 23, ss.137 - 143, 2017.
ISNAD	Uzun, Çağlar vd. "Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies". Diagnostic and Interventional Radiology 23/2 (2017), 137-143.