Yıl: 2016 Cilt: 10 Sayı: 4 Sayfa Aralığı: 283 - 296 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Akut Romatizmal Ateş

Öz:
Akut romatizmal ateş grup A streptokok farenjitinin çoklu organ sistemini etkileyen enflamatuvar bir bağ dokusu hastalığıdır. En sık 5-15 yaş arasında görülmekle birlikte; 5 yaş altındaki olgular, toplam hasta sayısının %3-5'ini oluşturmaktadır. Antibiyotiklerin yaygın kullanımı ile akut romatizmal ateş insidansı azalmasına rağmen dünyada 19/100.000 çocuğu etkilediği ve gelişmekte olan ülkelerde edinilmiş kalp hastalıklarının en önemli nedeni olduğu bilinmektedir. Akut romatizmal ateş tanısı klinik bulgulardan oluşan güncellenmiş Jones kriterleri kullanılarak konulmaktadır. Ekokardiyografi bulguları tanı kriterleri içerisinde yer almasa da son yıllardaki önemleri giderek artmaktadır. Çünkü akut romatizmal ateş sonrası kalıcı kapak lezyonları prognozu belirleyen en önemli faktördür.
Anahtar Kelime:

Konular: Romatoloji Pediatri

Acute Rheumatic Fever

Öz:
Acute rheumatic fever is an inflammatory connective tissue disease of group A streptococcal pharyngitis that affects multiple organ systems. Although it is common between the ages of 5 and 15, the patients under five years of age comprise 3-5% of the total number. The incidence of acute rheumatic fever had been declining even before the use of antibiotics became widespread; however, the disease has been estimated to affect 19 per 100,000 children worldwide and it remains the most important cause of acquired heart disease in developing countries. Acute rheumatic fever is diagnosed with the clinical findings using the modified Jones criteria. The role of echocardiography has increased in recent years but the diagnostic criteria do not include echocardiography findings. Permanent valve lesions are the most important factors determining the prognosis of acute rheumatic fever.
Anahtar Kelime:

Konular: Romatoloji Pediatri
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
  • Saltık İL. Akut romatizmal ateş. The Journal of Current Pediatrics 2007;5 Özel sayı 1:156-9.
  • Galal ME, Medhat ME, Khalid AS, Howaida GE. Rheumatic fever and rheumatic heart disease. In: Garson A, Bricker JT, Fisher DJ, Neish SR (eds). The Science and Practice of Pediatric Cardiology, 2nd ed. Baltimore: Williams and Wilkins, 1998:1691-724.
  • Ayoub EM. Acute rheumatic fever. In: Allen HD, Gutgesel HP, Clark EB, Driscoll DJ (eds). Moss and Adams' Heart Disease in Infants, Children and Adolescents, 6th ed. Philadelphia: Lippincott Williams and Wilkins, 2001:1226-41.
  • Bernstein D. Acquired heart disease In: Behr- man RE, Kliegman RM, Jenson HB (eds). Nelson Textbook of Pediatrics, 17th ed. Philadelphia: WB Saunders, 2004:1565-72.
  • Cilliers AM. Rheumatic fever and its management. BMJ 2006;333:1153-6.
  • Carapetis JR, Mc Donald M, Wilson N. Acute rheumatic fever. Lancet 2005;366:155-66.
  • Dajani AS. Rheumatic fever in braunwald heart disease. In: Braunwald E (ed). A Textbook of Cardiovascular Medicine. 5th ed. Philadelphia: WB Saunders Co, 1997:1769-75.
  • Özer S, Halkaoğlu O, Ozkutlu S, Çeliker A, Alehan D, Karagöz T. Childhood acute rheumatic fever in Ankara, Turkey. Turk J Pediatr 2005;47:120-4.
  • Carapetis JR, Steer AC, Mulholland EK, Weber M. The global burden of group A streptococcal diseases. Lancet Infect Dis 2005;5:685-94.
  • Tibazarwa KB, Volmink JA, Mayosi BM. Incidence of acute rheumatic fever in the world: A systematic review of population- based studies. Heart 2008;94:1534-40.
  • Miyake CY, Gauvreau K, Tani LY, Sundel RP, Newburger JW. Characteristics of children discharged from hospitals in the United States in 2000 with the diagnosis of acute rheumatic fever. Pediatrics 2007;120:503-8.
  • Akalın F. Akut romatizmal ateş ve yenilikler. Türk Ped Arş 2007;42:85-93.
  • Mayosi BM. A proposal for eradication of rheumatic fever in our lifetime. SAMJ 2006;96:229-30.
  • Mbewu AD. Rheumatic heart disease is a neglected disease of poverty requiring a multisectoral approach for control and eradication. SAMJ 2006;96:231-2.
  • Yuko-Jowi C, Bakari M. Echocardiographic patterns of juvenile rheumatic heart disease at the Kenyatta National Hospital, Nairobi. East Afr Med J 2005;82:514-9.
  • Saraçlar M, Ertuğrul A, Özme ve Ajun A. Akut romatizmal ateş insidansı ve romatizmal kalp hastalıklarının prevalansı. Türk Kardiyoloji Derneği Arşivi 1978;7:50-5.
  • Beyazova U, Benli D, Beyazova M. Akut romatizmal ateş görülme sıklığı. Çocuk Sağ Hast Derg 1987;2:76-8.
  • Veasy LG, Tani LY, Hill HR. Persistence of acute rheumatic fever in the intermountain area of the United States. J Pediatr 1994;124:9-
  • Karademir S, Demirçeken F, Atalay S, Demircin G, Sipahi T, Teziç T. Acute rheumatic fever in children in the Ankara area in 1980-1989. Acta Pediatr 1994;83:862-5.
  • Madden S, Kelly L. Update on acute rheumatic fever; it stil exists in remote communities. Can Fam Physician 2009;55:475-8.
  • Narin N, Mutlu F, Argun M, Ozyurt A, Pamukcu O, Baykan A, et al. Incidence and clinical features of acute rheumatic fever in Kayseri, Central Anatolia 1998-2011. Cardiol Young 2015;25:745-51.
  • Canter B, Olguntürk R, Tunaoğlu S. Rheumatic fever in children under 5 years old. Pediatrics 2004;114:329-30.
  • Wang C, Liu C, Li Y, Liu M. Adult onset acute rheumatic fever. Possible resurgence in southern Taiwan. J Clin Rheumatol 2005;11:146-9.
  • Tani LY, Veasy G, Minich L, Shaddy RE. Rheumatic fever in children younger than 5 years: Is the presentation different? Pediatrics 2003;112:1065-8.
  • Paulo LT, Terreri MT, Barbosa CM, Len CA, Hilário MO. Is rheumatic fever a more severe disease in pre-school children? Acta Reumatol Port 2009;34:66-70.
  • Westlake RM, Graham TP, Edwards KM. An outbraek of acute rheumatic fever in Tennessee. Pediatr Infect Dis J 1990;2:97-100.
  • Yılmaz E, Doğan Y, Yaşar F, Aygün D, Gürgöze K. Akut romatizmal ateşli hastaların değerlendirilmesi. Klinik Bilimler & Doktor 1999;5: 511-6.
  • Anita KM, Zaidi and Donald A. Goldman. Rheumatic fever in the Nelson textbook of pediatrics. Kliegman RM, Behrman RE, Jenson HB, Stanton BF (eds). 18 th edition. Philadelphia: WB Saunders Company, 2007:1140-5.
  • Bryant PA, Robins- Browne R, Carapetis JR, Curtis N. Some of the people, some of the time: Susceptibility to acute rheumatic fever. Circulation 2009;119:742-53.
  • Aksu G, Bayram N, Ulger Z, Ozturk C, Ozyurek RA, Bakiler RA, et al. Inverse relationship between the ratio of ICAM-1 expressing lymphocytes and serum TGF-?1 concentrations in acute rheumatic fever. J Autoimmun 2005;25:141-9.
  • Berdeli A, Celik HA, Özyürek R, Aydin HH. Involvement of immunoglobulin Fc?RIIA and Fc?RIIIB gene polymorphisms in susceptibility to rheumatic fever. Clinical Biochemistry 2004;37: 925-9.
  • Berdeli A, Çelik HA, Özyürek R, Doğrusöz B, Aydın HH. TRL-2 gene Arg 753Gln polymorphism is strongly associated with acute rheumatic fever in children. J Mol Med 2005;83:535-42.
  • Braunwald E. Heart Disease. A Textbook of Cardiovascular Medicine. Rheumatic fever and the rheumatic diseases of the heart. 1992;56:1721-30.
  • Owlia M, Mirza M. Acute rheumatic fever: Over Estimation or misconception? Int J Cardiol 2013;174:53-8.
  • Tunger A, Çavuşoğlu C, Korkmaz M. Streptokoklar ve enterokoklar. Mikrobiyoloji. 2. baskı. İzmir:Asya Tıp Yayıncılık, 2002:51-68.
  • Levinson W, Jawetz E. Gram positive cocci in Medical Microbiology and Immunology. A Lange medical book. Simon& Schuster co. 5th ed. Stanford Connecticut, 1998:78-86.
  • Martin JM, Barbadora KA. Continued high caseload of rheumatic fever in Western Pennsylvania: Possible rheumatogenic emm types of streptococcus pyogenes. J Pediatr 2006;149:58-63.
  • Quinn A, Kosanke S, Fichetti VA, Factor SM, Cunningham MW. Induction of autoimmune valvular heart disease by recombinant streptococcal M protein. Infect Immun 2001;69:4072-8.
  • Mc Donald M, Currie BJ, Carapetis JR. Acute rheumatic fever: A chink in the chain that links the heart to the throat? Lancet Infect Dis 2004;4:240-5.
  • Kaplan EL. Pathogenesis of acute rheumatic fever and rheumatic heart disease; Evasive after half a century of clinical, epidemiological and laboratory investigation. Heart 2005;91:3-4.
  • Wedu BG, McGuire JW. Origin of the Aschoff body. Ann Rheu Dis 1963;22:127-31.
  • Hutchins GM, Paige KT. Possible origin of cardial Aschoff bodies of rheumatic fever from nerves. John Hopkins Med J 1973;132:315- 19.
  • Daie JB, Beachey FH. Multiple heart cross-reactive epitopes of streptococcal M proteins. J Exp Med 1985;161:113.
  • Fae KC, Oshiro SE, Toubert A, Charron D, Kalil J, Guilherme L. How an autoimmune reaction triggered by molecular mimicry between streptococcal M protein and cardiac tissue proteins leads to heart lesions in rheumatic heart disease. J Autoimmun 2005;24:101-9.
  • Guilherme L, Cyry P, Demarchi LM. Rheumatic heart disease: Proinflamatory cytokines play arole in the progression and maintenance of valvular lesions. Am J Pathol 2004;165:1583-91.
  • Balat A, Kılınç M, Cekmen MB, Güler E, Yürekli M, Sahinöz S, et al. Adrenomedullin and total nitrite levels in children with acute rheumatic fever. Clin Bioc Hem 2005;38:526-30.
  • Chopra P, Wanniang J, Sampath Kumar A. Immunohistochemical and histochemical profile of Aschoff bodies in rheumatic carditis in excised left atrial appendages: An immunoperoxide study in fresh and paraffin embedded tissue. Int J Cardiol 1992;3482:199-207.
  • Veasy LG. Rheumatic fever. T. Duckett Jones and the rest of the story. Cardiol Young 1995;5:293-391.
  • Akalın F, Ünver T, Başaran M. Cardiac troponin-T in acute rheumatic fever. Marmara Medical Journal 2001;14:84-8.
  • Narula J, Chopra P, Talwar KK, Reddy KS, Vasan RS, Tandon R, et al. Does endomyocardial biopsy aid in the diagnosis of active rheumatic carditis. Circulation 1993;88:2198-205.
  • Polat TB, Yalçın Y, Akdeniz C, Zeybek C, Erdem A, Celebi A. QT dispersion in acute rheumatic fever. Cardiol Young 2006;16:141-6.
  • Li Y, Pan Z, Ji Y, Zhang H, Archard LC. Herpes simplex virus type 1 infection in rheumatic valvar disease. Heart 2005;91:87-8.
  • Aschoff L. Zur myocardistisfrage. Dtsch Ges 1904;8:46-53.
  • Schoen FJ. The heart. In: Cotran RS, Kumar V, Collins Teds (eds). Robbins Pathological Basis of Disease. 6 th century. Philadelphia: WB. Saunders Co, 1999:570-3.
  • Spina GS, Sampaio RO, Branco CE, Miranda GB, Rosa VE, Tarasoutchi F. Incidental histological diagnosis of acute rheumatic myocarditis: Case report and review of the literature. Front Pediatr 2014;2:126.
  • Burke RJ, Chang C. Diagnostic criteria of acute rheumatic fever. Autoimmun Rev 2014;13:503-7.
  • Ferreri P. Proceedings of the Jones criteria workshop. Circulation 2002;106:2521-3.
  • No authors listed. Jones criteria (revised) for guidance in the diagnosis of rheumatic fever. Circulation 1965;32:664-8.
  • Jones TD. The diagnosis of rheumatic fever. JAMA 1944;126:481- 4.
  • Burke Rebecca J, Chang C. Diagnostic criteria of acute rheumatic fever. Autoimmunity Reviews 2014;13:503-7.
  • Narula J, Chandrasekhar Y, Rahimtoola. Diagnosis of active rheumatic carditis. The echoes of change. Circulation 1999;100:1576- 81.
  • Guidelines for the diagnosis of rheumatic fever. Jones criteria, 1992 update. Special Writing Group of the Committee on rheumatic fever, endocarditis, and Kawasaki disease of the council on cardiovascular disease in the young of the American Heart Association. JAMA 1992;268:2069-73.
  • Onat T. Akut romatizmal ateş ve romatizmal kardit. Romatizmal kardit. Çocuk Sağlığı ve Hastalıkları Kitabı. İstanbul: Eksen Basın Yayın, 1999:558-95.
  • Ozdemir O, Oguz D, Atmaca E, Sanli C, Yildirim A, Olgunturk R. Cardiac troponin T in children with acute rheumatic carditis. Pediatr Cardiol 2011;32:55-8.
  • Mohindro R, Pannu HS, Mohan B, Kumar N, Dhooria HS, Sehgal A, et al. Syncope in a middle aged male due to acute rheumatic fever. Indian Heart J 2004;56:668-9.
  • Kula S, Olguntürk R, Özdemir O. Two unusual presentations of acute rheumatic fever. Cardiol Young 2005;15:514-6.
  • Unal N, Kosecik M, Saylam S, Kır M, Paytoncu S, Kumtepe S. Cardiac tamponade in acute rheumatic fever. Int J Cardiol 2005;103:217-8.
  • Ayabakan C, Akalın F. Akut romatizmal ateşin değişen yüzü. Anadolu Kardiyoloji Dergisi 2004;4:359-60.
  • Tubridy-Clark M, Carapetis JR. Subclinical carditis in rheumatic fever; A Systematic review. Int J Cardiol 2007;119:54-8.
  • Özkutlu S, Hallıoğlu O, Ayabakan C. Evaluation of subclinical valvar disease in patients with rheumatic fever. Cardiol Young 2003;13:495-9.
  • Özdemir O, Işık S, Abacı A, Hızlı S, Akelma AZ, Kışlal FM ve ark. Akut romatizmal ateşte sessiz düşman: Subklinik kardit. Turk Kardiyol Dern Ars 2011;39:41-6.
  • Vijayalakshmi IB, Mithravinda J, Deva ANP. The role of echocardiography in diagnosing carditis in the setting of rheumatic fever. Cardiol Young 2005;15:583-86.
  • www.nhf.org.nz/files/ Guide for use of echocardiography in acute rheumatic fever.
  • Harlan GA, Tani LY, Byington CL. Rheumatic fever presenting as monoarticular arthritis. Pediatr Infect Dis J 2006;25:743-6.
  • Williamson L, Bowness P, Mowat A, Östman-Smith I. Difficulties in diagnosing acute rheumatic fever- arthritis may be short lived and carditis silent. BMJ 2000;320:362-5.
  • Olguntürk R, Canter B, Tunaoğlu FS, Kula S. Review of 609 patients with rheumatic fever in terms of revised and updated Jones criteria. Int J Cardiol 2006;112:91-8.
  • Tutar E. Akut romatizmal ateş ve poststreptokoksik reaktif artrit. Türkiye Klinikleri J Pediatr Sci 2008;4:107-13.
  • El Said GM, Sanour KA. Acute rheumatic fever. In: Garson A, Bricker JT, Mcnamara DG (eds). The Science and Practice of Pediatric Cardiology. Lea and Febiger. London:Philadelphia, 1990:1485-500.
  • Mercadante MT, Busatta GF, Lombroso PJ, Prado L, Rosario- Campos MC, Dovalle R, et al. The psychiatric symptoms of rheu- matic fever. Am J psychiatry 2000;157:2036-8.
  • Maia DP, Teixieira AL, Cunningham MCQ, Cardoso F. Obsessive compulsive behaviour, hyperactivity and attention deficit disorder in Sydenham chorea. Neurology 2005;64:1799-801.
  • Braunwald E. Heart disease. A textbook of cardiovascular medicine. Rheumatic fever and the rheumatic diseases of the heart. 1992;56:1721-30.
  • Sethi S, Kaushik K, Mohandas K, Sengupta C, Singh S, Sharma M. Anti-streptolysin O titres in normal healthy children of 5-15 years. Indian Pediatr 2003;40:1068-7.
  • Pereira BA, da Silva NA, Andrade LE, Lima FS, Gurian FC, de Almeida Netto JC. Jones criteria and underdiagnosis of acute rheumatic fever. Indian J Pediatr 2007;74:117-21.
  • Ralph A, Jcups S, McGough K, McDonald M, Currie BJ. The challenge of acute rheumatic fever diagnosis in a high-incidence population: A prospective study and proposed guide- lines for diagnosis in Australia's Northern Territory. Heart Lung Circ 2006; 15: 113-8.
  • Eisenberg MJ. Rheumatic heart disease in the developing world: Prevalence, prevention, and control. Eur Heart J 1993;14:122-8.
  • Lee JL, Naguwa SM, Cheema GS, Gershwin ME. Acute rheumatic fever and consequences: A persistent threat to developing nations in the 21st century. Autoimmun Rev 2009;9:117-23.
  • Binotto MA, Guillherme L, Tanaka AC. Rheumatic fever. Images Pediatr Cardiol 2002;11:12-25.
  • Eroğlu AG. Akut romatizmal ateş. Klinik Gelişim 2006;19 Özel Sayı: 75-80.
  • Park H, Cleary PP. Active and passive intranasal immunizations with streptococcal surface protein C5a peptidase prevent infection of murine nasal mucosa-associated lymphoid tissue, a functional homologue of human tonsils. Infect Immun 2005;73:7878-86.
  • Brandt ER, Good MF. Vaccine strategies to prevent rheumatic fever. Immunol Res 1999;19:89-103.
  • Thatai D, Turi ZG. Current Guidelines for the Treatment of patients with Rheumatic Fever. Drugs 1999;57:545-55.
  • Ciliers AM, Manyemba J, Saloojee HH. Anti-inflammatory treatment for carditis in acute rheumatic fever. Cochrane Database Syst Rev 2003;2:CD 00 3176.
  • Genel F, Arslanoglu S, Uran N, Saylan B. Sydenham's chorea; Clinical findings and comparison of the efficacies of sodium valproate and carbamazepine regimens. Brain Dev 2002;24:73-6.
  • Karaaslan S, Demirören S, Oran B, Baysal T, Başpınar O, Uçar C. Criteria for jud- ging the improvement in subclinical rheumatic carditis. Cardiol Young 2003;13:500-5.
  • Meira ZMA, Goulart EMA, Mota CCC. Comparative study of clinical and Doppler Echocardiographic evaluations of the progression of valve diseases in children and adolescents with rheumatic fever. Arq Bras Cardiol 2006;86:32-8.
  • Meira ZMA, Goulart EMA, Colosimo EA, Mota CCC. Long term follow up of rheumatic fever and predictors of severe rheumatic valvular disease in Brazilian children and adolescents. Heart 2005; 91:1019-22.
  • McDonald M, Brown A, Noonan S, Carapetis JR. Preventing recurrent rheumatic fever: The role of register based programmes. Heart 2005;91:1131-3.
APA KÖKSAL A, GÜLTEKİN SOYLU A, Özdemir O (2016). Akut Romatizmal Ateş. , 283 - 296.
Chicago KÖKSAL Ali Osman,GÜLTEKİN SOYLU Asiye,Özdemir Osman Akut Romatizmal Ateş. (2016): 283 - 296.
MLA KÖKSAL Ali Osman,GÜLTEKİN SOYLU Asiye,Özdemir Osman Akut Romatizmal Ateş. , 2016, ss.283 - 296.
AMA KÖKSAL A,GÜLTEKİN SOYLU A,Özdemir O Akut Romatizmal Ateş. . 2016; 283 - 296.
Vancouver KÖKSAL A,GÜLTEKİN SOYLU A,Özdemir O Akut Romatizmal Ateş. . 2016; 283 - 296.
IEEE KÖKSAL A,GÜLTEKİN SOYLU A,Özdemir O "Akut Romatizmal Ateş." , ss.283 - 296, 2016.
ISNAD KÖKSAL, Ali Osman vd. "Akut Romatizmal Ateş". (2016), 283-296.
APA KÖKSAL A, GÜLTEKİN SOYLU A, Özdemir O (2016). Akut Romatizmal Ateş. Türkiye Çocuk Hastalıkları Dergisi, 10(4), 283 - 296.
Chicago KÖKSAL Ali Osman,GÜLTEKİN SOYLU Asiye,Özdemir Osman Akut Romatizmal Ateş. Türkiye Çocuk Hastalıkları Dergisi 10, no.4 (2016): 283 - 296.
MLA KÖKSAL Ali Osman,GÜLTEKİN SOYLU Asiye,Özdemir Osman Akut Romatizmal Ateş. Türkiye Çocuk Hastalıkları Dergisi, vol.10, no.4, 2016, ss.283 - 296.
AMA KÖKSAL A,GÜLTEKİN SOYLU A,Özdemir O Akut Romatizmal Ateş. Türkiye Çocuk Hastalıkları Dergisi. 2016; 10(4): 283 - 296.
Vancouver KÖKSAL A,GÜLTEKİN SOYLU A,Özdemir O Akut Romatizmal Ateş. Türkiye Çocuk Hastalıkları Dergisi. 2016; 10(4): 283 - 296.
IEEE KÖKSAL A,GÜLTEKİN SOYLU A,Özdemir O "Akut Romatizmal Ateş." Türkiye Çocuk Hastalıkları Dergisi, 10, ss.283 - 296, 2016.
ISNAD KÖKSAL, Ali Osman vd. "Akut Romatizmal Ateş". Türkiye Çocuk Hastalıkları Dergisi 10/4 (2016), 283-296.