The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department

UÇAR, Yıldız; erdem, sami; GÜL, MEHMET; UÇAR KARABULUT, KEZİBAN

The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department

Keziban UÇAR KARABULUT, (Başkent Üniversitesi Konya Hastanesi, Acil Tıp Anabilim Dalı, Konya, Türkiye)

Mehmet GÜL, (Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Acil Tıp Anabilim Dalı, Konya, Türkiye)

Yıldız UÇAR, (Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi, Biyokimya Anabilim Dalı, Konya, Türkiye)

Sami ERDEM (Diyarbakır Anma Hastanesi, Göğüs Hastalıkları Bölümü, Diyarbakır, Türkiye)

Çukurova Üniversitesi Tıp Fakültesi Dergisi

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Yıl: 2016 Cilt: 41 Sayı: 1 Sayfa Aralığı: 51 - 54 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department

Öz:

Amaç: Akut pankreatit, değişken klinik özelliklere sahip olması ve tanı yöntemlerindeki yetersizlikler nedeniyle acil serviste bazen tanı güçlüğü yaşanmaktadır. Tanı koyduracak olmadığından tanısı çoğu zaman zor ve geç konabilmektedir. aktivasyonunun bir göstergesi olup makrofajlardan salınan bir enzimdir. Çalışmamızda akut pankreatitin erken tanısında neopterinin rolünün belirlenmesi amaçlandı. Gereç ve Yöntem: Karın ağrısı şikayeti ile yatırılan laboratuar ve görüntüleme yöntemleri ile akut pankreatit tanısı konulan 39 hasta ile sağlıklı 30 kontrol çalışmaya dahil edildi. Alınan numunelerden amilaz, lipaz, kolesterol ve abdominalultrasonografi ve abdominal bilgisayarlı tomografi ile kesinleştirildi. Bulgular: Akut pankreatit olan hastaların Neopterin değerleri sağlıklı gruba göre anlamlı yüksek olarak tespit edildi. Sonuç: Neopterin birtakım inflamatuar ve otoimmün durumlarda yükselen bir belirteçtir. Akut pankreatitin erken tanısında ve şiddetinin belirlenmesinde önemli olabileceğini düşünmekteyiz. Bu konuda daha ileri deneysel ve klinik çalışmalara ihtiyaç vardır.

Anahtar Kelime:

Konular: Cerrahi

Acil servise başvuran akut pankreatit hastalarının tanısında neopterinin rolü

Öz:

Purpose: There are difficulties observed in the diagnosis of acute pancreatitis in emergency departments due to its different clinical properties and the insufficiencies in the methods of diagnosis. Since there is no specific biochemical indicator, the diagnosis is made usually late or with difficulty. Neopterine is an enzyme secreted from the macrophages and is an indicator of cellular immunity activation. The aim of this study was to determine the role of neopterine in the early diagnosis of acute pancreatitis . Material and Methods: 39 patients, who had been hospitalized with the complaints of abdominal pain and diagnosed as acute pancreatitis via laboratory and screening methods, and 30 healthy controls were included in the study. Amylase, lipase, cholesterol and neopterine were measured in the patients' samples. The diagnoses were confirmed with abdominal ultrasound and computed tomography. Results: The neopterine values in patients with acute pancreatitis were significantly higher than those of the control group. Conclusion: Neopterine is an indicator which is elevated in certain inflammatory and autoimmune situations. We believe that it is important in the early diagnosis of acute pancreatitis. Further experimental and clinical studies should be conducted on the subject.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	UÇAR KARABULUT K, GÜL M, UÇAR Y, erdem s (2016). The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. , 51 - 54.
Chicago	UÇAR KARABULUT KEZİBAN,GÜL MEHMET,UÇAR Yıldız,erdem sami The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. (2016): 51 - 54.
MLA	UÇAR KARABULUT KEZİBAN,GÜL MEHMET,UÇAR Yıldız,erdem sami The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. , 2016, ss.51 - 54.
AMA	UÇAR KARABULUT K,GÜL M,UÇAR Y,erdem s The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. . 2016; 51 - 54.
Vancouver	UÇAR KARABULUT K,GÜL M,UÇAR Y,erdem s The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. . 2016; 51 - 54.
IEEE	UÇAR KARABULUT K,GÜL M,UÇAR Y,erdem s "The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department." , ss.51 - 54, 2016.
ISNAD	UÇAR KARABULUT, KEZİBAN vd. "The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department". (2016), 51-54.

APA	UÇAR KARABULUT K, GÜL M, UÇAR Y, erdem s (2016). The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. Çukurova Üniversitesi Tıp Fakültesi Dergisi, 41(1), 51 - 54.
Chicago	UÇAR KARABULUT KEZİBAN,GÜL MEHMET,UÇAR Yıldız,erdem sami The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. Çukurova Üniversitesi Tıp Fakültesi Dergisi 41, no.1 (2016): 51 - 54.
MLA	UÇAR KARABULUT KEZİBAN,GÜL MEHMET,UÇAR Yıldız,erdem sami The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. Çukurova Üniversitesi Tıp Fakültesi Dergisi, vol.41, no.1, 2016, ss.51 - 54.
AMA	UÇAR KARABULUT K,GÜL M,UÇAR Y,erdem s The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. Çukurova Üniversitesi Tıp Fakültesi Dergisi. 2016; 41(1): 51 - 54.
Vancouver	UÇAR KARABULUT K,GÜL M,UÇAR Y,erdem s The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department. Çukurova Üniversitesi Tıp Fakültesi Dergisi. 2016; 41(1): 51 - 54.
IEEE	UÇAR KARABULUT K,GÜL M,UÇAR Y,erdem s "The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department." Çukurova Üniversitesi Tıp Fakültesi Dergisi, 41, ss.51 - 54, 2016.
ISNAD	UÇAR KARABULUT, KEZİBAN vd. "The role of neopterine in the diagnosis of patients with acute pancreatitis on admission to the emergency department". Çukurova Üniversitesi Tıp Fakültesi Dergisi 41/1 (2016), 51-54.