Oftalmolojide Botulinum Nörotoksini Kullanımı
Yıl: 2016 Cilt: 46 Sayı: 6 Sayfa Aralığı: 282 - 290 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Oftalmolojide Botulinum Nörotoksini Kullanımı
Öz: Botulinum nörotoksini (BoNT), insanlarda tedavi amaçlı ve kırışıklıkların önlenmesinde kozmetik amaçlı kullanılmaya başlanmış olan ilk biyolojik toksindir. Uygun kullanımda kas kontraksiyon gücünü ve/veya salgı bezi sekresyonunu azaltır. BoNT'nin en sıklıkla kullanıldığı alan üst yüz bölgesidir [glabella, alın, kaşlar ve lateral kantus kırışıklıkları (kaz ayakları)]. Estetikte kırışıklıklara neden olan kasları gevşeterek kalıcı olmayan bir düzelmeye neden olur. BoNT değişik oftalmik hastalıklarda yaygın olarak kullanılmaktadır. BoNT'nin etkisi geçicidir; ama tekrar eden enjeksiyonlardan sonra tedavi amaçlı etkinlik süresi genellikle uzar. Tedavi genellikle iyi tolere edilmektedir. Tedavi ile ilişkili komplikasyonlar ve yan etkiler nadir ve geçicidir. Komplikasyonlar komşu kas gruplarında meydana gelen zayıflama (kemodenervasyon), immünolojik mekanizmalar ve enjeksiyon tekniklerine bağlı olarak gelişmektedir. Bilimsel literatür değerlendirilerek BoNT'nin oftalmoloji ile ilgili hastalıklarda güncel tedavi endikasyonları, dozları, komplikasyonları ve kontrendikasyonları incelenmiştir. Bunlar; estetik amaçlı, şaşılık, blefarospazm, hemifasiyal spazm, göz kapak retraksiyonu, entropium, lakrimal hipersekresyon sendromu ve fasiyal paralizidir.
Anahtar Kelime: Konular:
Use of Botulinum Neurotoxin in Ophthalmology
Öz: Botulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum toxin treatment are the upper face, including the glabella, forehead, brows, and lateral canthal lines or crow's feet. By relaxing the muscles causing wrinkles, non-permanent results may be achieved with its use. BoNT has gained widespread use in a variety of ophthalmic diseases. The effect of BoNT is temporary, but the therapeutic benefit is usually maintained even after repeated injections. Treatment is usually well tolerated. Complications and side effects associated with the treatment are rare and temporary. Complications occur due to weakness (chemodenervation) of adjacent muscle groups, immunological mechanisms and injection technique. Current therapeutic indications, doses, complications and contraindications of BoNT use in the following disorders related to ophthalmology were investigated: aesthetic use, strabismus, blepharospasm, hemifacial spasm, eyelid retraction, entropion, lacrimal hypersecretion syndrome, and facial paralysis.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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| APA | BAŞAR E, ARICI C (2016). Oftalmolojide Botulinum Nörotoksini Kullanımı. , 282 - 290. |
| Chicago | BAŞAR Emel,ARICI CEYHUN Oftalmolojide Botulinum Nörotoksini Kullanımı. (2016): 282 - 290. |
| MLA | BAŞAR Emel,ARICI CEYHUN Oftalmolojide Botulinum Nörotoksini Kullanımı. , 2016, ss.282 - 290. |
| AMA | BAŞAR E,ARICI C Oftalmolojide Botulinum Nörotoksini Kullanımı. . 2016; 282 - 290. |
| Vancouver | BAŞAR E,ARICI C Oftalmolojide Botulinum Nörotoksini Kullanımı. . 2016; 282 - 290. |
| IEEE | BAŞAR E,ARICI C "Oftalmolojide Botulinum Nörotoksini Kullanımı." , ss.282 - 290, 2016. |
| ISNAD | BAŞAR, Emel - ARICI, CEYHUN. "Oftalmolojide Botulinum Nörotoksini Kullanımı". (2016), 282-290. |
| APA | BAŞAR E, ARICI C (2016). Oftalmolojide Botulinum Nörotoksini Kullanımı. Türk Oftalmoloji Dergisi, 46(6), 282 - 290. |
| Chicago | BAŞAR Emel,ARICI CEYHUN Oftalmolojide Botulinum Nörotoksini Kullanımı. Türk Oftalmoloji Dergisi 46, no.6 (2016): 282 - 290. |
| MLA | BAŞAR Emel,ARICI CEYHUN Oftalmolojide Botulinum Nörotoksini Kullanımı. Türk Oftalmoloji Dergisi, vol.46, no.6, 2016, ss.282 - 290. |
| AMA | BAŞAR E,ARICI C Oftalmolojide Botulinum Nörotoksini Kullanımı. Türk Oftalmoloji Dergisi. 2016; 46(6): 282 - 290. |
| Vancouver | BAŞAR E,ARICI C Oftalmolojide Botulinum Nörotoksini Kullanımı. Türk Oftalmoloji Dergisi. 2016; 46(6): 282 - 290. |
| IEEE | BAŞAR E,ARICI C "Oftalmolojide Botulinum Nörotoksini Kullanımı." Türk Oftalmoloji Dergisi, 46, ss.282 - 290, 2016. |
| ISNAD | BAŞAR, Emel - ARICI, CEYHUN. "Oftalmolojide Botulinum Nörotoksini Kullanımı". Türk Oftalmoloji Dergisi 46/6 (2016), 282-290. |
