Yıl: 2016 Cilt: 22 Sayı: 1 Sayfa Aralığı: 17 - 23 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon

Öz:
Amaç: Bu çalışmada amacımız Trabzon ilinde ayakta tedavi kliniğine başvuran hastalarda osteoporoz (OP) risk faktörlerinin kemik mineral yoğunluğu (KMY) ile ilişkisini belirlemektir.Gereç ve Yöntem: Çalışmaya OP veya osteopeni tanılı 201 hasta dahil edildi. Hastaların sosyodemografik özellikleri kaydedildi ve standardize araştırma formu araştırmacı hekim tarafından dolduruldu. KMY ölçümleri dual enerji X-ray taraması ile lomber omurga ve femur boynundan yapıldı.Bulgular: Hastaların yaş ortalaması 61,47±10,57 yıl (182 kadın/19 erkek) idi. Yüz on beş hasta (%57,2) osteoporotik, 86 hasta (%42) osteopenikti. Yaş ile femoral T skorları arasında negatif yönde anlamlı korelasyon bulundu. Gebelik sayısı lomber T skorları ile negatif yönde anlamlı korelasyon gösterdi. Vücut kitle indeksi ve günlük çay tüketimi ile femoral T skorları arasında ihmal edilebilir pozitif yönde korelasyon tespit edildi. Menarş yaşı, menopoz yaşı, toplam laktasyon süresi, ve günlük kalsiyum tüketimi ile KMY arasında herhangi bir korelasyon bulunmadı.Sonuç: OP için yöresel risk faktörlerinin tanımlanması klinik uygulamalarda hastaların OP risk yönetimine faydalı olabilir
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel Hematoloji

Trabzon'da Ayaktan Poliklinik Merkezimize Başvuran Hastalarda Kemik Mineral Yoğunluğu ile Osteoporoz Risk Faktörleri Arasındaki İlişki

Öz:
Objective: Our aim was to identify the relationship of osteoporosis (OP) risk factors with bone mineral density (BMD) in patients admitted our outpatient clinic in Trabzon.Materials and Methods: Two hundred one patients with OP or osteopenia were included in this study. Sociodemographic characteristics of the patients were recorded and a standardized interview was employed by the researcher physician. BMD values were measured by dual energy X-ray absorptiometry at lumbar spine and femoral neck.Results: The mean age of the patients was 61.47±10.57 years (182 females/19 males). One hundred fifteen patients (57.2%) were osteoporotic and 86 (42.8%) were osteopenic. A significant negative correlation was found between age and femoral neck T scores. The number of pregnancies showed a significant negative correlation with lumbar T scores. Body mass index and daily tea consumption showed a negligible positive correlation with femoral neck T scores. No association was found between age at menarche, age at menopause, total lactation duration, daily calcium intake and T scores of lumbar spine and femoral neck.Conclusions: Identification of regional OP risk factors may be useful for the OP risk management of patients in clinical practice
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel Hematoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • Consensus Development Conference: Diagnosis, prophylaxis and treatment of osteoporosis. Am J Med 1993;94:645-50.
  • Cohen AJ, Roe FJ. Review of risk factors for osteoporosis with particular reference to a possible aetiological role of dietary salt. Food Chem Toxicol 2000;38:237-53.
  • Unni S, Yao Y, Milne N, Gunning K, Curtis JR, LaFleur J. An evaluation of clinical risk factors for estimating fracture risk in postmenopausal osteoporosis using an electronic medical record database. Osteoporos Int 2015;26:581-7.
  • Tuzun S, Eskiyurt N, Akarırmak U, Sarıdoğan M, Senocak M, Johansson H, et al. Incidence of hip fracture and prevalence of osteoporosis in Turkey: The FRACTURK study. Osteoporos Int 2012;23:949-55.
  • Kanis JA, Melton LJ, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res 1994;9:1137-41.
  • Yates AA, Schlicker SA, Suitor CW. Dietary Reference Intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706.
  • Riggs BL, Melton LJ. The prevention and treatment of osteoporosis. N Engl J Med 1992;327:620-7.
  • Torgerson DJ, Campbell MK, Reid DM. Life style, environmental and medical factors influencing peak bone mass in women. Br J Rheumatol 1995;34:620-4.
  • Johnston CC Jr, Longcope C. Premenopausal bone loss-a risk factor for osteoporosis. N Eng J Med 1990;323:1271-3.
  • Kröger H, Tuppurainen M, Honkanen R, Alhava E, Saarikoski S. Bone mineral density and risk factors for osteoporosis- a population based study of 1600 perimenopausal women. Calcif Tissue Int 1994;55:1-7.
  • Melson F, Mosekilde L. The role of bone biopsy in the diagnosis of metabolic bone disease. Orthop Clin North Am 1981;12:571-602.
  • Raisz LG. Local and systemic factors in pathogenesis of osteoporosis. N Eng J Med 1988;318:818-28.
  • Albrand G, Munoz F, Sornay-Rendu E, DuBoeuf F, Delmas PD. Independent predictors of all osteoporosis-related fractures in healthy postmenopausal women: The OFELY Study. Bone 2003;32:78-85.
  • Bartl R, Frisch B. Osteoporosis. Diagnosis, Prevention, Treatment. 1st edition: Springer-Verlag Berlin Heidelberg; 2004.
  • Heidari B, Hosseini R, Javadian Y, Bijani A, Sateri MH, Nouroddini HG. Factors affecting bone mineral density in postmenopausal women. Arch Osteoporos 2015;10:15.
  • Broussard DL, Magnus JH. Risk assesment and screening for low bone mineral density in multi-ethnic population of women and men: Does one approach fit all? Osteoporos Int 2004;15:349-60.
  • Hannan MT, Felson DT, Dawson-Hughes B, Tucker KL, Cupples LA, Wilson PW, et al. Risk factors for longitudinal bone loss in elderly men and women: The Framingham Osteoporosis Study. J Bone Miner Res 2000;15:710-20.
  • Bendavid EJ, Shan J, Barrett-Connar E. Factors associated with bone mineral density in middle-aged men. J Bone Miner Res 1996;11:1185-90.
  • Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, et al. The study of osteoporotic fractures. Risk factors of hip fracture in white women. N Eng J Med 1995:332;767-73.
  • Dargent-Molina P, Piault S, Bréart G. A triage strategy based on clinical risk factors for selecting elderly women for treatment or bone densitometry: The EPIDOS prospective study. Osteoporos Int 2005;16:898-906.
  • Kritz-Silverstein D, Barrett-Connor E. Early menopause, number of reproductive years, and bone mineral density in postmenopausal women. Am J Public Health 1993;83:983-8.
  • Hu JF, Zhao XH, Chen JS, Fitzpatrick J, Parpia B, Campbell TC. Bone density and lifestyle characteristics in premenopausal and postmenopausal Chinese women. Osteoporos Int 1994;4:288-97.
  • Sowers MR, Clark MK, Hollis B, Wallace RB, Jannausch M. Radial bone mineral density in pre and perimenopausal women. J Bone Miner Res 1992;7:647-57.
  • Bagur AC, Mautalen CA. Risk for developing osteoporosis in untreated premature menopause. Calcif Tissue Int 1992;51:4-7.
  • Davies MC, Hall ML, Jacobs HS. Bone mineral loss in young women with amenorrhoea. BMJ 1990;301:790-3.
  • Hassa H, Tanir HM, Senses T, Oge T, Sahin-Mutlu F. Related factors in bone mineral density of lumbal and femur in natural postmenopausal women. Arc Gynecol Obstet 2005;273:86-9.
  • Li HL, Zhu HM. Relationship between age of menarghe, menopause and other factors and postmenopause osteoporosis. Zhonghua Fu Chan Ke Za Zhi 2005;40:796-8.
  • Kalkwarf HJ. Hormonal and dietary regulation of changes in bone density during lactation and after weaning in women. J Mammary Gland Biol Neoplasia 1999;4:319-29.
  • Dursun N, Akın S, Dursun E, Sade I, Korkusuz F. Influence of duration of total breast feeding on bone mineral density in a Turkish population: Does the priority of risk factors differ from society to society? Osteoporos Int 2006;17:651-5.
  • Yazici S, Korkmaz U, Erkan M, Korkmaz N, Erdem Baki A, Alçelik A, et al. The effect of breast-feeding duration on bone mineral density in postmenopausal Turkish women: A population based study. Arch Med Sci 2011;7:486-92.
  • Khoo CC, Woo J, Leung PC, Kwok A, Kwok T. Determinants of bone mineral density in older postmenopausal Chinese women. Climacteric 2011;14:378-83.
  • Gur A, Nas K, Cevik R, Sarac AJ, Ataoglu S, Karakoc M. Influence of number of pregnancies on bone mineral density in postmenopausal women of different age groups. J Bone Miner Metab 2003;21:234-41.
  • Melton LJ, Bryant SC, Wahner HW, O'Fallon WM, Malkasian GD, Judd HL, et al. Influence of breastfeeding and other reproductive factors on bone mass later in life. Osteoporosis Int 1993;3:76- 83.
  • Laitinen K, Välimäki M, Keto P. Bone mineral density measured by dual energy X-ray absorptiometry in healthy Finnish women. Calcif Tissue Int 1991;48:224-31.
  • Sioka C, Fotopoulos A, Georgiou A, Xourgia X, Papadopoulos A, Kalef-Ezra JA. Age at menarche, age at menopause and duration of fertility as risk factors for osteoporosis. Climacteric 2010;13:63- 71.
  • Uzun Ö, Köklü K, Özel S, Yılmaz Şahin A, Ünsal Delialioğlu S, Kulaklı F. Evaluation of gynecological risk factors in osteoporosis. Acta Oncol Tur 2014;47:11-5.
  • Bauer DC, Browner WS, Cauley JA, Orwoll ES, Scott JC, Black DM, et al. Factors associated with appendicular bone mass in older women. Ann Intern Med 1993;118:657-65.
  • Hernández-Avila M, Stampfer MJ, Ravnikar VA, Willett WC, Schiff I, Francis M, et al. Caffeine and other predictors of bone density among pre- and perimenopausal women. Epidemiology 1993;4:128-34.
  • Hoover PA, Webber CE, Beaumont LF, Blake JM. Postmenopausal bone mineral density: Relationship to calcium intake, calcium absorption, residual estrogen, body composition and physical activity. Can J Physiol Pharmacol 1996;74:911-7.
  • Hegarty VM, May HM, Khaw KT. Tea drinking and bone mineral density in older women. Am J Clin Nutr 2000;71:1003-7.
  • Wu CH, Yang YC, Yao WJ, Lu FH, Wu JS, Chang CJ. Epidemiological evidence of increased bone mineral density in habitual tea drinkers. Arch Intern Med 2002;162:1001-6.
  • Johnell O, Gullberg B, Kanis JA, Allander E, Elffors L, Dequeker J, et al. Risk factor for hip fracture in European women: The MEDOS Study. Mediterranean Osteoporosis Study. J Bone Miner Res 1995;10:1802-15.
  • Kanis J, Johnell O, Gullberg B, Allander E, Elffors L, Ranstam J, et al. Risk factors for hip fractures in men from southern Europe: The MEDOS Study. Mediterranean Osteoporosis Study. Osteoporos Int 1999;9:45-54.
  • Umay E, Tamkan U, Gündoğdu İ, Umay S, Çakcı A. The effect of osteoporosis risk factors on bone mineral density. Turk J Osteoporos 2011;17:44-50.
  • Eaton-Evans J. Osteoporosis and the role of diet. Br J Biomed Sci 1994;5:358-70.
  • Dawson-Hughes B, Harris SS, Krall EA, Dallal GE. Effect of calcium and vitamin D supplementation on bone density in men and women 65 years old age or older. N Engl J Med 1997;337:670-6.
  • Riggs BL, O'Fallon WM, Muhs J, O'Connor MK, Kumar R, Melton LJ. Long term effects of calcium supplementation on serum parathyroid hormone level, bone turnover and bone loss in elderly women. J Bone Miner Res 1998;13:168-74.
  • Özdemir F, Demirbağ Kabayel D, Türe M. Do dietary Calcium Intake and Hormone Replacement Therapy Affect Bone Mineral Density in Women? Balkan Med J 2008;25:105-9.
  • Michaëlsson K, Bergström R, Holmberg L, Mallmin H, Wolk A, Ljunghall S. A high dietary calcium intake is needed for a positive effect on bone density in Swedish postmenopausal women. Osteoporos Int 1997;7:155-61.
  • Sahin Onat Ş, Ünsal Delialioğlu S, Özel S. The relationship between osteoporotic risk factors and bone mineral density. Turk J Osteoporos 2013;19:74-80.
APA SERDAROĞLU BEYAZAL M, ÇAPKIN E, Karkucak M, GÜLER M, ÇAKIRBAY H, Tosun M (2016). The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. , 17 - 23.
Chicago SERDAROĞLU BEYAZAL Münevver,ÇAPKIN Erhan,Karkucak Murat,GÜLER MUSTAFA,ÇAKIRBAY Haşim,Tosun Mehmet The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. (2016): 17 - 23.
MLA SERDAROĞLU BEYAZAL Münevver,ÇAPKIN Erhan,Karkucak Murat,GÜLER MUSTAFA,ÇAKIRBAY Haşim,Tosun Mehmet The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. , 2016, ss.17 - 23.
AMA SERDAROĞLU BEYAZAL M,ÇAPKIN E,Karkucak M,GÜLER M,ÇAKIRBAY H,Tosun M The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. . 2016; 17 - 23.
Vancouver SERDAROĞLU BEYAZAL M,ÇAPKIN E,Karkucak M,GÜLER M,ÇAKIRBAY H,Tosun M The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. . 2016; 17 - 23.
IEEE SERDAROĞLU BEYAZAL M,ÇAPKIN E,Karkucak M,GÜLER M,ÇAKIRBAY H,Tosun M "The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon." , ss.17 - 23, 2016.
ISNAD SERDAROĞLU BEYAZAL, Münevver vd. "The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon". (2016), 17-23.
APA SERDAROĞLU BEYAZAL M, ÇAPKIN E, Karkucak M, GÜLER M, ÇAKIRBAY H, Tosun M (2016). The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. Türk Osteoporoz Dergisi, 22(1), 17 - 23.
Chicago SERDAROĞLU BEYAZAL Münevver,ÇAPKIN Erhan,Karkucak Murat,GÜLER MUSTAFA,ÇAKIRBAY Haşim,Tosun Mehmet The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. Türk Osteoporoz Dergisi 22, no.1 (2016): 17 - 23.
MLA SERDAROĞLU BEYAZAL Münevver,ÇAPKIN Erhan,Karkucak Murat,GÜLER MUSTAFA,ÇAKIRBAY Haşim,Tosun Mehmet The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. Türk Osteoporoz Dergisi, vol.22, no.1, 2016, ss.17 - 23.
AMA SERDAROĞLU BEYAZAL M,ÇAPKIN E,Karkucak M,GÜLER M,ÇAKIRBAY H,Tosun M The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. Türk Osteoporoz Dergisi. 2016; 22(1): 17 - 23.
Vancouver SERDAROĞLU BEYAZAL M,ÇAPKIN E,Karkucak M,GÜLER M,ÇAKIRBAY H,Tosun M The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon. Türk Osteoporoz Dergisi. 2016; 22(1): 17 - 23.
IEEE SERDAROĞLU BEYAZAL M,ÇAPKIN E,Karkucak M,GÜLER M,ÇAKIRBAY H,Tosun M "The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon." Türk Osteoporoz Dergisi, 22, ss.17 - 23, 2016.
ISNAD SERDAROĞLU BEYAZAL, Münevver vd. "The Relationship of Osteoporosis Risk Factors with Bone Mineral Density in Patients Admitted Our Outpatient Clinic in Trabzon". Türk Osteoporoz Dergisi 22/1 (2016), 17-23.