Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome

GÜREL, Ahmet; YILMAZ, Ahsen; Oran, Mustafa; TULUBAŞ, Feti; TURAN, Filiz; Mete, Rafet; YILDIZ, Zeynep Deniz

Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome

Feti TULUBAŞ, (Namık Kemal Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Tekirdağ, Türkiye)

Mustafa ORAN, (Namık Kemal Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Tekirdağ, Türkiye)

Rafet METE, (Namık Kemal Üniversitesi, Tıp Fakültesi, Gastroenteroloji Anabilim Dalı, Tekirdağ, Türkiye)

Filiz TURAN, (Namık Kemal Üniversitesi, Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Tekirdağ, Türkiye)

Ahsen YILMAZ, (Namık Kemal Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Tekirdağ, Türkiye)

Zeynep Deniz YILDIZ, (Namık Kemal Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Tekirdağ, Türkiye)

Ahmet GÜREL (Namık Kemal Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim Dalı, Tekirdağ, Türkiye)

Turkish Journal of Medical Sciences

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Yıl: 2014 Cilt: 44 Sayı: 6 Sayfa Aralığı: 967 - 971 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome

Öz:

Aim: Irritable bowel syndrome (IBS), a functional disorder of the bowel, has been thought to result from immune activation. The aim of this study was to evaluate macrophage migration inhibitory factor (MMIF) and monocyte chemotactic protein-1 (MCP-1) levels in IBS patients. Materials and methods: We enrolled 30 IBS patients and 30 healthy controls. The MMIF and MCP-1 levels of all patients and controls were detected using commercial enzyme-linked immunosorbent assay kits. Results: Serum MMIF and MCP-1 levels were markedly higher in IBS patients than in controls. White blood cell, neutrophil, lymphocyte, monocyte, eosinophil, and basophil counts did not differ significantly between groups. Conclusion: These results show that alterations in MMIF and MCP-1 affect the proinflammatory process. They also suggest that MMIF and MCP-1 may play a substantial role in IBS.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	TULUBAŞ F, Oran M, Mete R, TURAN F, YILMAZ A, YILDIZ Z, GÜREL A (2014). Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. , 967 - 971.
Chicago	TULUBAŞ Feti,Oran Mustafa,Mete Rafet,TURAN Filiz,YILMAZ Ahsen,YILDIZ Zeynep Deniz,GÜREL Ahmet Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. (2014): 967 - 971.
MLA	TULUBAŞ Feti,Oran Mustafa,Mete Rafet,TURAN Filiz,YILMAZ Ahsen,YILDIZ Zeynep Deniz,GÜREL Ahmet Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. , 2014, ss.967 - 971.
AMA	TULUBAŞ F,Oran M,Mete R,TURAN F,YILMAZ A,YILDIZ Z,GÜREL A Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. . 2014; 967 - 971.
Vancouver	TULUBAŞ F,Oran M,Mete R,TURAN F,YILMAZ A,YILDIZ Z,GÜREL A Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. . 2014; 967 - 971.
IEEE	TULUBAŞ F,Oran M,Mete R,TURAN F,YILMAZ A,YILDIZ Z,GÜREL A "Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome." , ss.967 - 971, 2014.
ISNAD	TULUBAŞ, Feti vd. "Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome". (2014), 967-971.

APA	TULUBAŞ F, Oran M, Mete R, TURAN F, YILMAZ A, YILDIZ Z, GÜREL A (2014). Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. Turkish Journal of Medical Sciences, 44(6), 967 - 971.
Chicago	TULUBAŞ Feti,Oran Mustafa,Mete Rafet,TURAN Filiz,YILMAZ Ahsen,YILDIZ Zeynep Deniz,GÜREL Ahmet Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. Turkish Journal of Medical Sciences 44, no.6 (2014): 967 - 971.
MLA	TULUBAŞ Feti,Oran Mustafa,Mete Rafet,TURAN Filiz,YILMAZ Ahsen,YILDIZ Zeynep Deniz,GÜREL Ahmet Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. Turkish Journal of Medical Sciences, vol.44, no.6, 2014, ss.967 - 971.
AMA	TULUBAŞ F,Oran M,Mete R,TURAN F,YILMAZ A,YILDIZ Z,GÜREL A Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. Turkish Journal of Medical Sciences. 2014; 44(6): 967 - 971.
Vancouver	TULUBAŞ F,Oran M,Mete R,TURAN F,YILMAZ A,YILDIZ Z,GÜREL A Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome. Turkish Journal of Medical Sciences. 2014; 44(6): 967 - 971.
IEEE	TULUBAŞ F,Oran M,Mete R,TURAN F,YILMAZ A,YILDIZ Z,GÜREL A "Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome." Turkish Journal of Medical Sciences, 44, ss.967 - 971, 2014.
ISNAD	TULUBAŞ, Feti vd. "Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome". Turkish Journal of Medical Sciences 44/6 (2014), 967-971.