PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses

KISA, ÖZGÜL; BİROL, Ahu; GÜNEY, Çakır; KOÇAK, Mukadder; ERKEK, Emel

PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses

Mukadder KOÇAK, (Kırıkkale Üniversitesi, Tıp Fakültesi, Dermatoloji Anabilim Dalı, Kırıkkale, Türkiye)

Emel ERKEK, (Girilmedi)

Özgül KISA, (Girilmedi)

Çakır GÜNEY, (Girilmedi)

Ahu BİROL (Girilmedi)

Turkish Journal of Medical Sciences

2 1

Yıl: 2003 Cilt: 33 Sayı: 2 Sayfa Aralığı: 83 - 87 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses

Öz:

Background: Herpes simplex virus (HSV) is the primary herpesvirus implicated to have a causal role in erythema multiforme (EM), both in cases with an antecedent herpetic infection and in idiopathic EM. However, the association of EM with several other viral infections has been clearly documented. Objective: The aim of the present study was to investigate a hypothetical role for the remaining members of the herpesvirus family in HSV-negative cases of EM. Methods: Fresh, unfixed lesional skin biopsies from 25 patients with HSV-negative EM were studied for the presence of Epstein-Barr virus(EBV), cytomegalovirus (CMV), human herpesvirus-6 (HHV-6) and human herpesvirus-7 (HHV-7) by using polymerase chain reaction (PCR) and nested PCR. Results: PCR revealed the absence of specific DNA sequences for EBV, CMV, HHV-6 and HHV-7 in all lesional EM specimens analyzed. Conclusion: These findings do not support an etiological role for non-HSV members of the herpesvirus family in HSV-negative EM.

Anahtar Kelime: Herpesvirus 7, Human Herpesvirus 4, Human Epstein barr virus Herpesvirus 6, Human Polymerase Chain Reaction Cytomegalovirus Herpesviridae

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KOÇAK M, ERKEK E, KISA Ö, GÜNEY Ç, BİROL A (2003). PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. , 83 - 87.
Chicago	KOÇAK Mukadder,ERKEK Emel,KISA ÖZGÜL,GÜNEY Çakır,BİROL Ahu PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. (2003): 83 - 87.
MLA	KOÇAK Mukadder,ERKEK Emel,KISA ÖZGÜL,GÜNEY Çakır,BİROL Ahu PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. , 2003, ss.83 - 87.
AMA	KOÇAK M,ERKEK E,KISA Ö,GÜNEY Ç,BİROL A PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. . 2003; 83 - 87.
Vancouver	KOÇAK M,ERKEK E,KISA Ö,GÜNEY Ç,BİROL A PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. . 2003; 83 - 87.
IEEE	KOÇAK M,ERKEK E,KISA Ö,GÜNEY Ç,BİROL A "PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses." , ss.83 - 87, 2003.
ISNAD	KOÇAK, Mukadder vd. "PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses". (2003), 83-87.

APA	KOÇAK M, ERKEK E, KISA Ö, GÜNEY Ç, BİROL A (2003). PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. Turkish Journal of Medical Sciences, 33(2), 83 - 87.
Chicago	KOÇAK Mukadder,ERKEK Emel,KISA ÖZGÜL,GÜNEY Çakır,BİROL Ahu PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. Turkish Journal of Medical Sciences 33, no.2 (2003): 83 - 87.
MLA	KOÇAK Mukadder,ERKEK Emel,KISA ÖZGÜL,GÜNEY Çakır,BİROL Ahu PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. Turkish Journal of Medical Sciences, vol.33, no.2, 2003, ss.83 - 87.
AMA	KOÇAK M,ERKEK E,KISA Ö,GÜNEY Ç,BİROL A PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. Turkish Journal of Medical Sciences. 2003; 33(2): 83 - 87.
Vancouver	KOÇAK M,ERKEK E,KISA Ö,GÜNEY Ç,BİROL A PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses. Turkish Journal of Medical Sciences. 2003; 33(2): 83 - 87.
IEEE	KOÇAK M,ERKEK E,KISA Ö,GÜNEY Ç,BİROL A "PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses." Turkish Journal of Medical Sciences, 33, ss.83 - 87, 2003.
ISNAD	KOÇAK, Mukadder vd. "PCR analysis of HSV-negative erythema multiforme for the expression of other herpesviruses". Turkish Journal of Medical Sciences 33/2 (2003), 83-87.