Evaluation of Lung Cancer Patients with Distant Organ Metastasis
Yıl: 2016 Cilt: 6 Sayı: 2 Sayfa Aralığı: 115 - 120 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Evaluation of Lung Cancer Patients with Distant Organ Metastasis
Öz: AMAÇ: Kanser ekonomik olarak gelişmiş ülkelerde önde gelen ölüm nedenidir ve gelişmekte olan ülkelerde ikinci önde gelen ölüm nedenidir. Çalışmanın amacı, uzak organ metastaz olan akciğer kanserli hastaların ve metastazların sağkalım oranları üzerine etkisinin değerlendirilmesidir.YÖNTEM: Uzak organ metastazı olan akciğer kanserli hastalar çalışmaya alındı. Primer tümörlerin lokalizasyonu ve metastaz, metastaz histolojik tipleri, klinik belirti ve bulgular, tümör ve lenf nodlarının etkileşimi, sağkalım oranları üzerindeki metastazların etkisi değerlendirildi.BULGULAR: Çalışmaya 174 hasta dahil edildi. Hastaların sitolojik alt gruplarının küçük hücreli dışı akciğer kanseri (KHDAK) (%75,3) ve küçük hücreli akciğer kanseri (KHAK) (%24,7) olarak iki alt gruba ayrıldı.En sık metastaz bölgleri kemik (%41,4), kontralateral akciğer (%32,8), karaciğer (%23,9) beyin (%27), böbreküstü bezi (%19,5), plevra (%9,2) idi. KHDAK ve KHAK için en sık metastaz yerleri sırasıyla kemik ve karaciğer idi. Skuamöz hücreli karsinom beyin, kemik, böbreküstü ve karşı akciğerde metastaz en yaygın türü oldu. Metastatik plevra sıvıları çoğunlukla genellikle adenokarsinom ve karaciğer metastazları ise küçük hücreli akciğer kanserlerinde kaynaklanmıştır. Kemik ve beyin ile ilgili spesifik semptomların varlığı metastaz için güçlü belirleyicilerdi.SONUÇ: Kanserin tipi, metastaz sayısı, kilo kaybı, kötü performans status, kemik ve beyin metastazı yapan KHAK'lerinde semptomların olmamasının, karaciğer metastazında ise semptomların olmasının sağkalım oranları üzerine ters etkisi vardı. Hastaların klinik laboratuvar ve radyolojik bulguları bir bütün incelenmesi metazların tahmininde faydalı olurken, gereksiz cerrahiyi önlemiş olur.
Anahtar Kelime: Konular:
Uzak Organ Metastazlı Akciğer Kanseri Hastalarının Değerlendirilmesi**
Öz: AIM: Cancer is the leading cause of death in economically developed countries and the second leading cause of death in developing countries. The aim of the study was to evaluate distant organ metastasis in patients with lung cancer and the effect of metastasis on survival rates.METHODS: Lung cancer patients with distant organ metastasis were enrolled to the study. Localization of primary tumors and metastasis, histological types of the metastasis, clinical symptoms and signs, the interaction of tumor and lymph nodes, the effects of metastasis on survival rates were evaluated.RESULTS: 174 patients were included in the study. Cytologic subgroups of patients were subdivided as non-small cell lung cancer (NSCLC) (75.3%) and small cell lung cancer (SCLC) (24.7%). The most frequent metastatic sites were bone (41.4 %), contralateral lung (32.8%), liver (23.9%) brain (27%), adrenal gland (19,5%), pleura (9.2%). The most common metastasis sites for NSCLC and SCLC were bone and liver respectively. Squamous cell carcinoma was the most common type of metastases in brain, bone, adrenal and contralateral lung metastasis. Metastatic pleural effusions mostly originated from adenocarcinoma and liver metastasis generally originated from small cell lung cancer. Having specific symptoms related to bone and brain were powerful predictors for metastasis.CONCLUSION: Cytological types of the cancer, number of metastasis, weight loss, poor performance status, the absence of symptoms in SCLC with bone and brain metastasis, and presence of the symptoms in liver metastases had adverse effects on survival rates. Evaluation of patients with combination of clinical symptoms, laboratory and radiological findings as whole it may be helpful in predicting metastasis and may prevent unnecessary surgery.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ACAR P, ÜNSAL M, ALTINTAŞ N (2016). Evaluation of Lung Cancer Patients with Distant Organ Metastasis. , 115 - 120. |
| Chicago | ACAR Pınar,ÜNSAL Meftun,ALTINTAŞ Nejat Evaluation of Lung Cancer Patients with Distant Organ Metastasis. (2016): 115 - 120. |
| MLA | ACAR Pınar,ÜNSAL Meftun,ALTINTAŞ Nejat Evaluation of Lung Cancer Patients with Distant Organ Metastasis. , 2016, ss.115 - 120. |
| AMA | ACAR P,ÜNSAL M,ALTINTAŞ N Evaluation of Lung Cancer Patients with Distant Organ Metastasis. . 2016; 115 - 120. |
| Vancouver | ACAR P,ÜNSAL M,ALTINTAŞ N Evaluation of Lung Cancer Patients with Distant Organ Metastasis. . 2016; 115 - 120. |
| IEEE | ACAR P,ÜNSAL M,ALTINTAŞ N "Evaluation of Lung Cancer Patients with Distant Organ Metastasis." , ss.115 - 120, 2016. |
| ISNAD | ACAR, Pınar vd. "Evaluation of Lung Cancer Patients with Distant Organ Metastasis". (2016), 115-120. |
| APA | ACAR P, ÜNSAL M, ALTINTAŞ N (2016). Evaluation of Lung Cancer Patients with Distant Organ Metastasis. Kafkas Tıp Bilimleri Dergisi, 6(2), 115 - 120. |
| Chicago | ACAR Pınar,ÜNSAL Meftun,ALTINTAŞ Nejat Evaluation of Lung Cancer Patients with Distant Organ Metastasis. Kafkas Tıp Bilimleri Dergisi 6, no.2 (2016): 115 - 120. |
| MLA | ACAR Pınar,ÜNSAL Meftun,ALTINTAŞ Nejat Evaluation of Lung Cancer Patients with Distant Organ Metastasis. Kafkas Tıp Bilimleri Dergisi, vol.6, no.2, 2016, ss.115 - 120. |
| AMA | ACAR P,ÜNSAL M,ALTINTAŞ N Evaluation of Lung Cancer Patients with Distant Organ Metastasis. Kafkas Tıp Bilimleri Dergisi. 2016; 6(2): 115 - 120. |
| Vancouver | ACAR P,ÜNSAL M,ALTINTAŞ N Evaluation of Lung Cancer Patients with Distant Organ Metastasis. Kafkas Tıp Bilimleri Dergisi. 2016; 6(2): 115 - 120. |
| IEEE | ACAR P,ÜNSAL M,ALTINTAŞ N "Evaluation of Lung Cancer Patients with Distant Organ Metastasis." Kafkas Tıp Bilimleri Dergisi, 6, ss.115 - 120, 2016. |
| ISNAD | ACAR, Pınar vd. "Evaluation of Lung Cancer Patients with Distant Organ Metastasis". Kafkas Tıp Bilimleri Dergisi 6/2 (2016), 115-120. |
