Discordance Rates Between AMH and FSH in Different Age Groups

kuyucu, melda; ÖZKAYA, Enis; GÜNAYDIN, Seracettin; SELÇUK, Selçuk; KUTLU, Tayfun; Devranoğlu, Belgin; KÜÇÜKBAŞ, mehmet

Discordance Rates Between AMH and FSH in Different Age Groups

Selçuk SELÇUK, (Sağlık Bakanlığı, Zeynep Kamil Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul Türkiye)

Mehmet KÜÇÜKBAŞ, (Sağlık Bakanlığı, Zeynep Kamil Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul Türkiye)

Belgin DEVRANOĞLU, (Sağlık Bakanlığı, Zeynep Kamil Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul Türkiye)

Melda KUYUCU, (Sağlık Bakanlığı, Zeynep Kamil Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul Türkiye)

Seracettin GÜNAYDIN, (İstanbul Anadolu Batı Kamu Hastaneleri, İstanbul, Türkiye)

Enis ÖZKAYA, (Sağlık Bakanlığı, Zeynep Kamil Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul Türkiye)

Hüseyin Tayfun KUTLU (Sağlık Bakanlığı, Zeynep Kamil Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul Türkiye)

Journal of Clinical and Analytical Medicine

5 2

Yıl: 2016 Cilt: 7 Sayı: 5 Sayfa Aralığı: 621 - 624 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Discordance Rates Between AMH and FSH in Different Age Groups

Öz:

Amaç: Farklı yaş gruplarına göre anti-Müllerian hormon (AMH) ve folikül stimülan hormon (FSH) arasındaki diskordans oranının Türk kadın kohortunda araştırılması. Gereç ve Yöntem: Bu retrospektif çalışma, Zeynep Kamil Eğitim Araştırma Hastanesi infertilite kliniğinde gerçekleştirildi. Hastalar; yaş gruplarına göre AMH ve FSH arasındaki diskordansı değerlendirmek amacıyla <=30 yaş, 31-35 yaş, 36-39 yaş ve >= 40 yaş olmak üzere dört gruba ayrıldı. Diskordans oranı, AMH ve FSH median değerleri yaş gruplarına göre incelendi. Bulgular: Çalışmaya dahil edilme kriterlerini sağlayan 467 hasta çalışmaya dahil edildi. Hastaların %35.1'i (n=164) <= 30 yaş, %28.3'ü (n=132) 31-35 yaş arası, %22.7'si (n=106) 36-39 yaş arası ve %13.9'u (n=65) >=40 yaş idi. Diskordans oranı normal AMH-anormal FSH değeri olan hastalar için <=30, 31-35, 36-39, >=40 yaş hasta grupları için sırasıyla %4.2, %6.7, %11.0, %17.9 olarak saptandı. Normal FSH-anormal AMH değeri olan hastalarda diskordans oranı <=30, 31-35, 36-39, >=40 yaş hasta grupları için sırasıyla %6.2, %8.5, %16.7, %17.9 olarak tespit edildi. Tartışma: Diskordans oranının normal AMH-anormal FSH değeri olan ve anormal AMH-normal FSH değeri olan Çalışmamızın sonuçları ve literatürdeki sonuçlara göre farklı etnik gruplarda AMH ve FSH arasındaki diskordans oranlarının ve yaşa göre AMH ve FSH düzeylerinin farklılık gösterebileceği düşünülmektedir.

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Farklı Yaş Gruplarında AMH ve FSH Arasındaki Diskordans Oranları

Öz:

Aim: To evaluate the discordance rates between anti-Müllerian hormone (AMH) and follicle stimulating hormone (FSH) levels according to different age groups in a cohort of Turkish women. Material and Method: This retrospective study was conducted at infertility clinics of Zeynep Kamil Training and Research Hospital. Patients were divided into 4 groups as <= 30 years, 3135 years, 36-39 years, and >= 40 years to evaluate the discordance between AMH and FSH in terms of age. Discordance rates, and median level of AMH and of FSH were determined for each age group. Results: 467 patients who met the inclusion criteria were enrolled in the study. 35.1% (n=164), 28.3% (n=132), 22.7%(n=106), and 13.9% (n=65) of patients were <= 30 years, 3135 years, 36-39 years, and >= 40 years, respectively. The discordance rates in terms of normal AMH but abnormal FSH level were 4.2%, 6.7%, 11.0%, 17.9% in the <= 30, 31-35, 36-39, >=40 years age groups, respectively, whereas the discordance rates in terms of normal FSH but abnormal AMH levels were 6.2%, 8.5%, 16.7%, 17.9% in the same age groups, respectively. Discussion: Discordance rates steadily increased with advancing age both for concerning AMH-reassuring FSH and concerning FSH-reassuring AMH. Data from our study and the literature lead us to conclude that age-based AMH and FSH levels and also that discordance between these parameters may vary among different ethnic groups

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SELÇUK S, KÜÇÜKBAŞ m, Devranoğlu B, kuyucu m, GÜNAYDIN S, ÖZKAYA E, KUTLU T (2016). Discordance Rates Between AMH and FSH in Different Age Groups. , 621 - 624.
Chicago	SELÇUK Selçuk,KÜÇÜKBAŞ mehmet,Devranoğlu Belgin,kuyucu melda,GÜNAYDIN Seracettin,ÖZKAYA Enis,KUTLU Tayfun Discordance Rates Between AMH and FSH in Different Age Groups. (2016): 621 - 624.
MLA	SELÇUK Selçuk,KÜÇÜKBAŞ mehmet,Devranoğlu Belgin,kuyucu melda,GÜNAYDIN Seracettin,ÖZKAYA Enis,KUTLU Tayfun Discordance Rates Between AMH and FSH in Different Age Groups. , 2016, ss.621 - 624.
AMA	SELÇUK S,KÜÇÜKBAŞ m,Devranoğlu B,kuyucu m,GÜNAYDIN S,ÖZKAYA E,KUTLU T Discordance Rates Between AMH and FSH in Different Age Groups. . 2016; 621 - 624.
Vancouver	SELÇUK S,KÜÇÜKBAŞ m,Devranoğlu B,kuyucu m,GÜNAYDIN S,ÖZKAYA E,KUTLU T Discordance Rates Between AMH and FSH in Different Age Groups. . 2016; 621 - 624.
IEEE	SELÇUK S,KÜÇÜKBAŞ m,Devranoğlu B,kuyucu m,GÜNAYDIN S,ÖZKAYA E,KUTLU T "Discordance Rates Between AMH and FSH in Different Age Groups." , ss.621 - 624, 2016.
ISNAD	SELÇUK, Selçuk vd. "Discordance Rates Between AMH and FSH in Different Age Groups". (2016), 621-624.

APA	SELÇUK S, KÜÇÜKBAŞ m, Devranoğlu B, kuyucu m, GÜNAYDIN S, ÖZKAYA E, KUTLU T (2016). Discordance Rates Between AMH and FSH in Different Age Groups. Journal of Clinical and Analytical Medicine, 7(5), 621 - 624.
Chicago	SELÇUK Selçuk,KÜÇÜKBAŞ mehmet,Devranoğlu Belgin,kuyucu melda,GÜNAYDIN Seracettin,ÖZKAYA Enis,KUTLU Tayfun Discordance Rates Between AMH and FSH in Different Age Groups. Journal of Clinical and Analytical Medicine 7, no.5 (2016): 621 - 624.
MLA	SELÇUK Selçuk,KÜÇÜKBAŞ mehmet,Devranoğlu Belgin,kuyucu melda,GÜNAYDIN Seracettin,ÖZKAYA Enis,KUTLU Tayfun Discordance Rates Between AMH and FSH in Different Age Groups. Journal of Clinical and Analytical Medicine, vol.7, no.5, 2016, ss.621 - 624.
AMA	SELÇUK S,KÜÇÜKBAŞ m,Devranoğlu B,kuyucu m,GÜNAYDIN S,ÖZKAYA E,KUTLU T Discordance Rates Between AMH and FSH in Different Age Groups. Journal of Clinical and Analytical Medicine. 2016; 7(5): 621 - 624.
Vancouver	SELÇUK S,KÜÇÜKBAŞ m,Devranoğlu B,kuyucu m,GÜNAYDIN S,ÖZKAYA E,KUTLU T Discordance Rates Between AMH and FSH in Different Age Groups. Journal of Clinical and Analytical Medicine. 2016; 7(5): 621 - 624.
IEEE	SELÇUK S,KÜÇÜKBAŞ m,Devranoğlu B,kuyucu m,GÜNAYDIN S,ÖZKAYA E,KUTLU T "Discordance Rates Between AMH and FSH in Different Age Groups." Journal of Clinical and Analytical Medicine, 7, ss.621 - 624, 2016.
ISNAD	SELÇUK, Selçuk vd. "Discordance Rates Between AMH and FSH in Different Age Groups". Journal of Clinical and Analytical Medicine 7/5 (2016), 621-624.