Bloodstream Infections in a Neonatal Intensive Care Unit

Özbek, Erdal; İPEK, Mehmet Şah

Bloodstream Infections in a Neonatal Intensive Care Unit

Mehmet Şah İPEK, (Diyarbakır Çocuk Hastalıkları Hastanesi, Diyarbakır, Türkiye)

Erdal ÖZBEK (Diyarbakır Çocuk Hastalıkları Hastanesi, Diyarbakır, Türkiye)

Journal of Clinical and Analytical Medicine

6 0

Yıl: 2016 Cilt: 7 Sayı: 5 Sayfa Aralığı: 625 - 629 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Bloodstream Infections in a Neonatal Intensive Care Unit

Öz:

Amaç: Bir yenidoğan yoğun bakım ünitesindeki kan akımı enfeksiyonlarının dağılımını ve etken organizmaların antimikrobiyal duyarlılığını belirlemek. Gereç ve Yöntem: Türkiye Güneydoğu Anadolu Bölgesindeki Diyarbakır Kadın Doğum ve Çocuk Hastanesi yenidoğan yoğun bakım ünitesinde Mart 2011Mart 2014 tarihleri arasında kan kültür pozitifliği olan hastane kaynaklı sepsis tanılı yenidoğanlar geriye dönük olarak değerlendirildi. Bulgular: 142 yenidoğan bebekte toplam 148 etken izole edildi. En yaygın izole edilen mikroorganizmalar Klebsiella pneumoniae (%40.5) ve bir hastane salgını sonucu olarak Acinetobacter baumannii (%29.7) idi. İzole edilen K. Pneumoniae türlerinin %20'si, A.baumannii türlerinin ise %93.2'si çoklu-ilaç direnci olan türlerdi. Sepsis-ilişkili mortalite oranı, çoklu-ilaç direnci olan türlerle enfekte olgularda, çoklu-ilaç direnci olmayan türlerle (kandida hariç) enfekte olgulardan daha fazlaydı (%24'e karşı %9.7, p=0.032). Tartışma: Ünitemizde, kan akımı enfeksiyonları daha çok gram negatif bakteri kaynaklıydı. Çoklu-ilaç direnci olan türlerin neden olduğu kan akımı enfeksiyonları, daha yüksek sepsis-ilişkili mortalite oranı ile birliktedir

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Yenidoğan Yoğun Bakım Ünitesinde Kan Akımı Enfeksiyonları

Öz:

Aim: To determine the pattern of bloodstream infections (BSIs) and antimicrobial susceptibility of pathogens in a neonatal intensive care unit (NICU).Material and Method: Positive hemoculture of neonates diagnosed with nosocomial sepsis from March 2011 to March 2014 in the NICU of Diyarbakir Maternity and Children's Hospital, in the southeastern region of Anatolia, Turkey, were retrospectively reviewed. Results: A total of 148 pathogens were isolated in 142 neonates. The most common microorganisms isolated were Klebsiella pneumoniae (40.5%) and Acinetobacter baumannii (29.7%) which was a result of a hospital outbreak. Multi-drug resistant (MDR) strains accounted for 20.0% of K. pneumoniae isolates and 93.2% of A. baumannii isolates. The sepsis-attributable mortality rate was higher in cases infected with MDR strains than in cases infected without MDR strains or Candida spp (24% vs. 9.7%, p=0.032). Discussion: In our unit, BSIs were more often caused by Gram negative bacteria. BSIs caused by MDR strains were associated with a higher rate of sepsis-attributable mortality

Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	İPEK M, Özbek E (2016). Bloodstream Infections in a Neonatal Intensive Care Unit. , 625 - 629.
Chicago	İPEK Mehmet Şah,Özbek Erdal Bloodstream Infections in a Neonatal Intensive Care Unit. (2016): 625 - 629.
MLA	İPEK Mehmet Şah,Özbek Erdal Bloodstream Infections in a Neonatal Intensive Care Unit. , 2016, ss.625 - 629.
AMA	İPEK M,Özbek E Bloodstream Infections in a Neonatal Intensive Care Unit. . 2016; 625 - 629.
Vancouver	İPEK M,Özbek E Bloodstream Infections in a Neonatal Intensive Care Unit. . 2016; 625 - 629.
IEEE	İPEK M,Özbek E "Bloodstream Infections in a Neonatal Intensive Care Unit." , ss.625 - 629, 2016.
ISNAD	İPEK, Mehmet Şah - Özbek, Erdal. "Bloodstream Infections in a Neonatal Intensive Care Unit". (2016), 625-629.

APA	İPEK M, Özbek E (2016). Bloodstream Infections in a Neonatal Intensive Care Unit. Journal of Clinical and Analytical Medicine, 7(5), 625 - 629.
Chicago	İPEK Mehmet Şah,Özbek Erdal Bloodstream Infections in a Neonatal Intensive Care Unit. Journal of Clinical and Analytical Medicine 7, no.5 (2016): 625 - 629.
MLA	İPEK Mehmet Şah,Özbek Erdal Bloodstream Infections in a Neonatal Intensive Care Unit. Journal of Clinical and Analytical Medicine, vol.7, no.5, 2016, ss.625 - 629.
AMA	İPEK M,Özbek E Bloodstream Infections in a Neonatal Intensive Care Unit. Journal of Clinical and Analytical Medicine. 2016; 7(5): 625 - 629.
Vancouver	İPEK M,Özbek E Bloodstream Infections in a Neonatal Intensive Care Unit. Journal of Clinical and Analytical Medicine. 2016; 7(5): 625 - 629.
IEEE	İPEK M,Özbek E "Bloodstream Infections in a Neonatal Intensive Care Unit." Journal of Clinical and Analytical Medicine, 7, ss.625 - 629, 2016.
ISNAD	İPEK, Mehmet Şah - Özbek, Erdal. "Bloodstream Infections in a Neonatal Intensive Care Unit". Journal of Clinical and Analytical Medicine 7/5 (2016), 625-629.