THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS

GÜL, Serdar

THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS

Serdar GÜL (Kırıkkale University, Department of Infectious Diseases and Clinical Microbiology, Kırıkkale / Turkey)

Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi

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Yıl: 2015 Cilt: 48 Sayı: 2 Sayfa Aralığı: 69 - 73 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS

Öz:

AMAÇ: Koagulaz testi Staphylococcus aureus suşlarının tanımlanmasında ve ayrımında kullanılır. Bu şuşlarda metisilin direnci mortalite ve morbidite ile ilişkili bulunmuştur. Bu çalışmada S. aureus suşlarında metisilin duyarlılığı ve koagulaz üretimi arasındaki ilişki araştırılmıştır. GEREÇ VE YÖNTEMLER: Çalışmaya 108 S. aureus suşu alınmıştır. Suşların 43 tanesi metisilin dirençli ve 65 tanesi metisilin duyarlı idi. Koagulaz üretiminin saptanmasında tüp koagulaz testi kullanılmıştır. Tüpler birinci, ikinci, üçüncü, dördüncü ve 24. saatin sonunda pıhtı oluşumuna göre değerlendirilmiştir.BULGULAR: Sonuçlar üç grupta değerlendirilmiştir. Grup 1: Pıhtı oluşturmayan grup, Grup 2: Zayıf pıhtı oluşturan grup, Grup 3: Güçlü pıhtı oluşturan grup. Birinci ve ikinci saatin sonunda metisilin duyarlılığında grup 2 ve 3 arasında anlamlı bir sonuç bulunamamıştır. Fakat grup2 ve 3 arasında üçüncü saatin sonunda anlamlı bir ilişki saptanmıştır (p=0,036). Grup 3' teki suşların çoğunun metisiline duyarlı olduğu görülmüştür. SONUÇ: Çalışmanın sonuçlarına göre üçüncü saatin sonunda güçlü pıhtı oluşumu, S. aureus suşlarında metisilin duyarlılığı açısından yol gösterici olabilir

Anahtar Kelime:

Konular: Mikrobiyoloji Biyoteknoloji ve Uygulamalı Mikrobiyoloji Farmakoloji ve Eczacılık

STAPHYLOCOCCUS AUREUS SUŞLARINDA METİSİLİN DUYARLILIĞI VE KOAGULAZ ÜRETİMİ ARASINDAKİ İLİŞKİ

Öz:

OBJECTIVE: Coagulase test is used for diagnosing and differentiating Staphylococcus aureus strains. Methicillin resistance is associated with significant mortality and morbidity for S. aureus infections. This study aimed to evaluate the relationship between coagulase producing time and methicillin susceptibility in S. aureus. MATERIAL AND METHODS: One hundred and eight S. aureus strains were included in the study. Fourty three strains were methicillin resistant and sixty five were methicillin susceptible. The tube coagulase test was used for detecting coagulase production. The tubes were examined for clot formation at the end of the first, second, third, fourth and twenty fourth hour. RESULTS: Results were evaluated in three groups. Group 1: No clot formation, Group 2: Weak clot formation, Group 3: Strong clot formation. At the end of the first and second hour, there was no significant difference in methicillin susceptibility between group 2 and group 3. But there was a significant difference in methicillin susceptibility between group 2 and group 3 at the end of the third hour (p=0,036). Most of the bacteria in group 3 were susceptible to methicillin. CONCLUSION: According to the results of our study, strong clot formation at the end of the third hour may be indicative for methicillin susceptibility of S. aureus

Anahtar Kelime:

Konular: Mikrobiyoloji Biyoteknoloji ve Uygulamalı Mikrobiyoloji Farmakoloji ve Eczacılık

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	GÜL S (2015). THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. , 69 - 73.
Chicago	GÜL Serdar THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. (2015): 69 - 73.
MLA	GÜL Serdar THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. , 2015, ss.69 - 73.
AMA	GÜL S THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. . 2015; 69 - 73.
Vancouver	GÜL S THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. . 2015; 69 - 73.
IEEE	GÜL S "THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS." , ss.69 - 73, 2015.
ISNAD	GÜL, Serdar. "THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS". (2015), 69-73.

APA	GÜL S (2015). THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, 48(2), 69 - 73.
Chicago	GÜL Serdar THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi 48, no.2 (2015): 69 - 73.
MLA	GÜL Serdar THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, vol.48, no.2, 2015, ss.69 - 73.
AMA	GÜL S THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. 2015; 48(2): 69 - 73.
Vancouver	GÜL S THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi. 2015; 48(2): 69 - 73.
IEEE	GÜL S "THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS." Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, 48, ss.69 - 73, 2015.
ISNAD	GÜL, Serdar. "THE RELATIONSHIP BETWEEN COAGULASE PRODUCING TIME AND METHICILLIN SUSCEPTIBILITY IN STAPHYLOCOCCUS AUREUS". Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi 48/2 (2015), 69-73.