Wegener granulomatosis (WG) is a multisystemic disorder char- acterised by granulomatous inflammation of the respiratory sys- tem. The growing of proliferative tissue towards the larynx and trachea may cause airway obstruction on account of subglottic stenosis. In this situation, the surgical goal is to eliminate the air- way obstruction by providing natural airway anatomy. While mild lesions do not require surgical intervention, in fixed lesions, surgi- cal intervention is required, such as tracheostomy, laser resection and dilatation. In tracheostomised patients, granuloma formation surrounding the tracheostomy cannula may occur in the trachea. Inflammation and newly formed granulation tissue result in severe stenosis in the airways. During surgical treatment of such patients, airway management is important. In this case report, we will dis- cuss gas exchange and airway management with jet ventilation (JV) during excision of the granulation tissue with endolaryngeal laser surgery, leading to subglottic stenosis in tracheostomised pa- tients in WG