In the present study, it was aimed to investigate the arthritis cases occurring in calves not only with known methods including clinical findings, radiology and sinovial liquid analysis but also with other methods including indirect radiography, ultrasonography and histopathological analysis and implementation of findings into clinical practice. The study material was obtained between years 2006-2008, from the 40 calves admitted to the Veterinary Surgery Clinics of Faculty of Veterinary Medicine, University of Kafkas including thirtysix carpal, nine tarsal, four scapulohumeral, eight genu, two metacarpophalangeal, one interphalangeal, one metatarsophalangeal and one articulatio cubiti. Clinical examination, radiographic, ultrasonographic and histopathological findings were compared with each other. The results of the research used in the diagnosis of joint disease, direct radiographical examination was helpful for the determination of osteophyte formations occurring in the joint capsule and within the joint, erosive lesions and fractures. However, it was not satisfactory for the determination of the cartilage lesions. Artrography, which is a more advanced technique provided clearer and more detailed information about the status of the joint capsule and cartilage lesions. Moreover, ultrasound examination and joint capsule, synovial fluid, synovial membrane and cartilage provided more detailed information about the surface detected. In this study, in the clinical diagnosis of arthritis in calves, radiological, ultrasonographic and histopathological findings supported each other, especially in the early diagnosis of disease arthrographic and ultrasound findings provide important information.