Yıl: 2014 Cilt: 1 Sayı: 3 Sayfa Aralığı: 106 - 110 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Body composition in patients with rheumatoid arthritis is not different than healthy subjects

Öz:
Amaç: Romatoid artrit (RA) artmış kardiyovasküler hastalık (KVH) riskiyle ilişkilidir. Artmış vücut yağı, özellikle vücut yağının santral dağılımı, CVD için iyi bilinen bir risk faktörüdür. Vücut kompozisyonunda değişiklik RA'da daha önce tanımlanmıştır. Ancak, bu çalışmaların çoğu yaş ve cinsiyet eşleştirilmiş fakat vücut kitle indeksi (VKİ) eşleştirilmemiş kontrol gruplarıyla yapılmıştır. Bu çalışmanın amacı, RA hastalarında vücut kompozisyonunu değerlendirmek ve RA hastalarının vücut kompozisyonunu yaş, cinsiyet ve VKİ açısından eşleştirilmiş kontrol grubunkiyle karşılaştırmaktı. Materyal ve Metot: Çalışmaya 65 RA hastası (55 kadın ve 10 erkek; yaş ortalaması 54.9±10.8) ve 31 sağlıklı kontrol (25 kadın, 6 erkek; yaş ortalaması 53.8±8.6) dahil edildi. Ortalama hastalık süresi 9.2±9.6 yıldı. Vücut kompozisyonu antropometrik yöntemler (deri kıvrım kalınlıkları, vücut çevre ölçümleri), biyoimpedans analizi ve dual enerji X ışını absorbsiyometrisi (DXA) ile değerlendirildi. Viseral yağ dokusu (VYD) bilgisayarlı tomografi ile değerlendirildi. Bulgular: RA hastaları ve kontroller arasında total vücut yağı, bölgesel yağ dağılımı, total vucut suyu ve yağsız kitle açısından anlamlı fark yoktu. DXA ile değerlendirilen kemik mineral içeriği (KMİ) RA hastalarında anlamlı olarak daha düşüktü (p=0.004). Klinik hastalık aktivite indeksleri ve steroid tedavisi yumuşak doku vücut kompozisyonunu veya KMİ'yi etkilemedi. Sonuç: Yaş, cinsiyet ve total adipozite açısından benzer bireylere kıyasla en azından bazı RA hastaları yumuşak doku kompozisyonunda değişikliğe sahip değildir ve benzer sağlık riskleri taşıyabilirler.
Anahtar Kelime:

Konular: Romatoloji

Romatoid artritli hastalarda vücut kompozisyonu sağlıklı bireylerinkinden farklı değildir

Öz:
Objective: Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease (CVD). Increased body fat, particularly its central distribution, is a well-known risk factor for CVD. A change in body composition in RA has been described previously. However, in most of these studies, age- and sex- but not body mass index (BMI)-matched controls were used. The aim of this study was to evaluate body composition in RA patients and compare it with age-, sex-, and BMI-matched controls. Material and Methods: Sixty-five RA patients (55 females and 10 males; mean age 54.9 ± 10.8) and 31 healthy controls (25 females, 6 males; 53.8±8.6) were included in this study. Mean disease duration was 9.2±9.6 years. Body composition was assessed by anthropometric methods (skinfold thicknesses, body circumferences), bioimpedance analysis, and dual-energy X-ray absorptiometry (DXA). Visceral adipose tissue (VAT) was assessed with computed tomography.Results: There were no significant differences for total body fatness, regional fat distribution, and total body water and fat-free mass between RA patients and control subjects. Bone mineral content (BMC), assessed by DXA, was significantly lower in RA patients (p=0.004). Clinical disease activity indices and steroid treatment do not affect soft tissue body composition or BMC.Conclusion: At least some RA patients do not have soft tissue composition alterations and may have similar health risks in comparison with subjects with similar age, sex, and total adiposity
Anahtar Kelime:

Konular: Romatoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Akar S, Sari I, ÇÖMLEKÇİ A, Birlik M, ÖNEN F, GÖKTAY Y, ÖZAKSOY D, Akkoç N (2014). Body composition in patients with rheumatoid arthritis is not different than healthy subjects. , 106 - 110.
Chicago Akar Servet,Sari Ismail,ÇÖMLEKÇİ Abdurrahman,Birlik Merih,ÖNEN Fatoş,GÖKTAY Yiğit,ÖZAKSOY Dinç,Akkoç Nurullah Body composition in patients with rheumatoid arthritis is not different than healthy subjects. (2014): 106 - 110.
MLA Akar Servet,Sari Ismail,ÇÖMLEKÇİ Abdurrahman,Birlik Merih,ÖNEN Fatoş,GÖKTAY Yiğit,ÖZAKSOY Dinç,Akkoç Nurullah Body composition in patients with rheumatoid arthritis is not different than healthy subjects. , 2014, ss.106 - 110.
AMA Akar S,Sari I,ÇÖMLEKÇİ A,Birlik M,ÖNEN F,GÖKTAY Y,ÖZAKSOY D,Akkoç N Body composition in patients with rheumatoid arthritis is not different than healthy subjects. . 2014; 106 - 110.
Vancouver Akar S,Sari I,ÇÖMLEKÇİ A,Birlik M,ÖNEN F,GÖKTAY Y,ÖZAKSOY D,Akkoç N Body composition in patients with rheumatoid arthritis is not different than healthy subjects. . 2014; 106 - 110.
IEEE Akar S,Sari I,ÇÖMLEKÇİ A,Birlik M,ÖNEN F,GÖKTAY Y,ÖZAKSOY D,Akkoç N "Body composition in patients with rheumatoid arthritis is not different than healthy subjects." , ss.106 - 110, 2014.
ISNAD Akar, Servet vd. "Body composition in patients with rheumatoid arthritis is not different than healthy subjects". (2014), 106-110.
APA Akar S, Sari I, ÇÖMLEKÇİ A, Birlik M, ÖNEN F, GÖKTAY Y, ÖZAKSOY D, Akkoç N (2014). Body composition in patients with rheumatoid arthritis is not different than healthy subjects. European Journal of Rheumatology, 1(3), 106 - 110.
Chicago Akar Servet,Sari Ismail,ÇÖMLEKÇİ Abdurrahman,Birlik Merih,ÖNEN Fatoş,GÖKTAY Yiğit,ÖZAKSOY Dinç,Akkoç Nurullah Body composition in patients with rheumatoid arthritis is not different than healthy subjects. European Journal of Rheumatology 1, no.3 (2014): 106 - 110.
MLA Akar Servet,Sari Ismail,ÇÖMLEKÇİ Abdurrahman,Birlik Merih,ÖNEN Fatoş,GÖKTAY Yiğit,ÖZAKSOY Dinç,Akkoç Nurullah Body composition in patients with rheumatoid arthritis is not different than healthy subjects. European Journal of Rheumatology, vol.1, no.3, 2014, ss.106 - 110.
AMA Akar S,Sari I,ÇÖMLEKÇİ A,Birlik M,ÖNEN F,GÖKTAY Y,ÖZAKSOY D,Akkoç N Body composition in patients with rheumatoid arthritis is not different than healthy subjects. European Journal of Rheumatology. 2014; 1(3): 106 - 110.
Vancouver Akar S,Sari I,ÇÖMLEKÇİ A,Birlik M,ÖNEN F,GÖKTAY Y,ÖZAKSOY D,Akkoç N Body composition in patients with rheumatoid arthritis is not different than healthy subjects. European Journal of Rheumatology. 2014; 1(3): 106 - 110.
IEEE Akar S,Sari I,ÇÖMLEKÇİ A,Birlik M,ÖNEN F,GÖKTAY Y,ÖZAKSOY D,Akkoç N "Body composition in patients with rheumatoid arthritis is not different than healthy subjects." European Journal of Rheumatology, 1, ss.106 - 110, 2014.
ISNAD Akar, Servet vd. "Body composition in patients with rheumatoid arthritis is not different than healthy subjects". European Journal of Rheumatology 1/3 (2014), 106-110.