Minor salivary gland evaluation: Sjögren?s syndrome

KÜÇÜK, ulku; ÇETİN, Pınar; Sari, Ismail; Birlik, Merih; Sarioglu, Sulen

Minor salivary gland evaluation: Sjögren?s syndrome

Sülen SARIOĞLU, (Dokuz Eylül Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, İzmir, Türkiye)

Ülkü KÜÇÜK, (Tepecik Araştırma ve Eğitim Hastanesi, Patoloji Bölümü, İzmir, Türkiye)

Pınar ÇETİN, (Dokuz Eylül Üniversitesi Romatoloji Bilim Dalı, İzmir, Türkiye)

İsmail SARI, (Dokuz Eylül Üniversitesi Romatoloji Bilim Dalı, İzmir, Türkiye)

Ahmet Merih BİRLİK (Dokuz Eylül Üniversitesi Romatoloji Bilim Dalı, İzmir, Türkiye)

Turkish Journal of Medical Sciences

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Yıl: 2016 Cilt: 46 Sayı: 1 Sayfa Aralığı: 63 - 65 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Minor salivary gland evaluation: Sjögren?s syndrome

Öz:

Background/aim: We aimed to analyze the value of 3 serial sections, spaced 200 µm apart, for quantification of lymphocyte and plasma cell foci in minor salivary gland biopsy (MSGB). Materials and methods: Labial MSGBs from 69 patients with Sjögren s syndrome (SS) and scleroderma were used for this study. Each sample was prepared as 3 serial sections spaced 200 µm apart. Lymphocytic and plasma cell focus score (LFS, PFS) were determined for each section, and the diagnostic results were compared to those obtained from a single section. Results: For 22 of the 69 patients, all 3 sections were scored at <1 and interpreted as inconclusive for the presence of SS. For 20 cases, all 3 sections were scored at ≥1 and interpreted as diagnostic for SS. In the remaining 27 cases, the score was found to vary between sections. Plasma cell foci were observed in 11 cases, with 5 cases exhibiting a PFS of ≥1. Of those 5 cases, 4 also had a LFS of ≥1. Conclusion: Assessment of 3 serial sections in MSGB has the potential to improve accuracy of SS diagnosis by detecting specific features that may not have been detected in a single section. We concluded that data about the PFS require further evaluation.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Sarioglu S, KÜÇÜK u, ÇETİN P, Sari I, Birlik M (2016). Minor salivary gland evaluation: Sjögren?s syndrome. , 63 - 65.
Chicago	Sarioglu Sulen,KÜÇÜK ulku,ÇETİN Pınar,Sari Ismail,Birlik Merih Minor salivary gland evaluation: Sjögren?s syndrome. (2016): 63 - 65.
MLA	Sarioglu Sulen,KÜÇÜK ulku,ÇETİN Pınar,Sari Ismail,Birlik Merih Minor salivary gland evaluation: Sjögren?s syndrome. , 2016, ss.63 - 65.
AMA	Sarioglu S,KÜÇÜK u,ÇETİN P,Sari I,Birlik M Minor salivary gland evaluation: Sjögren?s syndrome. . 2016; 63 - 65.
Vancouver	Sarioglu S,KÜÇÜK u,ÇETİN P,Sari I,Birlik M Minor salivary gland evaluation: Sjögren?s syndrome. . 2016; 63 - 65.
IEEE	Sarioglu S,KÜÇÜK u,ÇETİN P,Sari I,Birlik M "Minor salivary gland evaluation: Sjögren?s syndrome." , ss.63 - 65, 2016.
ISNAD	Sarioglu, Sulen vd. "Minor salivary gland evaluation: Sjögren?s syndrome". (2016), 63-65.

APA	Sarioglu S, KÜÇÜK u, ÇETİN P, Sari I, Birlik M (2016). Minor salivary gland evaluation: Sjögren?s syndrome. Turkish Journal of Medical Sciences, 46(1), 63 - 65.
Chicago	Sarioglu Sulen,KÜÇÜK ulku,ÇETİN Pınar,Sari Ismail,Birlik Merih Minor salivary gland evaluation: Sjögren?s syndrome. Turkish Journal of Medical Sciences 46, no.1 (2016): 63 - 65.
MLA	Sarioglu Sulen,KÜÇÜK ulku,ÇETİN Pınar,Sari Ismail,Birlik Merih Minor salivary gland evaluation: Sjögren?s syndrome. Turkish Journal of Medical Sciences, vol.46, no.1, 2016, ss.63 - 65.
AMA	Sarioglu S,KÜÇÜK u,ÇETİN P,Sari I,Birlik M Minor salivary gland evaluation: Sjögren?s syndrome. Turkish Journal of Medical Sciences. 2016; 46(1): 63 - 65.
Vancouver	Sarioglu S,KÜÇÜK u,ÇETİN P,Sari I,Birlik M Minor salivary gland evaluation: Sjögren?s syndrome. Turkish Journal of Medical Sciences. 2016; 46(1): 63 - 65.
IEEE	Sarioglu S,KÜÇÜK u,ÇETİN P,Sari I,Birlik M "Minor salivary gland evaluation: Sjögren?s syndrome." Turkish Journal of Medical Sciences, 46, ss.63 - 65, 2016.
ISNAD	Sarioglu, Sulen vd. "Minor salivary gland evaluation: Sjögren?s syndrome". Turkish Journal of Medical Sciences 46/1 (2016), 63-65.