Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?

BİÇER, Hasan; ALSANCAK, Yakup; sivri, serkan; YAŞAR, Ayşe Saatcı; SİVRİ, Hatice Duygu Çiftçi; BİLGE, Mehmet; ALİ, Sina

Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?

Yakup ALSANCAK, (Ankara Atatürk Training and Research Hospital, Clinic of Cardiology, Ankara, Turkey)

Sina ALİ, (Ankara Atatürk Training and Research Hospital, Clinic of Cardiology, Ankara, Turkey)

Serkan SİVRİ, (Ankara Atatürk Training and Research Hospital, Clinic of Cardiology, Ankara, Turkey)

Hasan BİÇER, (Ankara Atatürk Training and Research Hospital, Clinic of Cardiology, Ankara, Turkey)

Hatice Duygu Çiftçi SİVRİ, (Ankara Atatürk Training and Research Hospital, Clinic of Emergency Medicine, Ankara, Turkey)

Ayşe Saatcı YAŞAR, (Ankara Atatürk Training and Research Hospital, Clinic of Cardiology, Ankara, Turkey)

Mehmet BİLGE (Ankara Atatürk Training and Research Hospital, Clinic of Cardiology, Ankara, Turkey)

Koşuyolu Kalp Dergisi

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Yıl: 2017 Cilt: 20 Sayı: 1 Sayfa Aralığı: 7 - 12 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?

Öz:

Giriş: Dolaşımdaki monosit sayısı yeni aterosklerotik plak gelişimi için öngördürücü bir faktördür. Ayrıca, yüksek dansiteli lipoprotein kolesterol (HDL) ile ateroskleroz arasında güçlü bir ters ilişki vardır. Monosit sayısı/HDL oranının (MHR) yeni bir inflamatuvar belirteç olduğu gösterilmiştir. Biz MHR ile safen ven greft hastalığı (SVGD) arasındaki ilişkiyi araştırmayı amaçladık.Hastalar ve Yöntem: Toplam 369 hasta 3 gruba bölündü (SVGD olan grup= 150, SVGD olmayan grup= 89, normal koroner arter grubu= 130). Bazal karakteristikler ve laboratuvar parametreleri kayıt edildi ve gruplar arasında karşılaştırıldı.Bulgular: Bazal karakteristiklere göre SVGD olan ve olmayan gruplarda, SVG yaşı ve sol ventrikül ejeksiyon fraksiyonu haricinde istatistiksel farklılık yoktu. C-reaktif protein, açlık kan şekeri ve ortalama platelet hacmi SVGD olan grupta SVGD olmayan gruba göre daha yüksekti (sırasıyla p değerleri= 0.008, 0.048 ve 0.042). MHR değeri SVGD olan, SVGD olmayan (p= 0.169) ve normal koroner arter grupları (p= 0.364) arasında istatistiksel farklılık göstermedi. CRP, SVGD için bağımsız öngördürücü faktör olarak bulundu.Sonuç: MHR ve koroner ateroskleroz arasında ilişki yoktu. MHR, SVGD için bir öngördürücü faktör değildi.

Anahtar Kelime:

Konular: Cerrahi

Monosit/ Yüksek Dansiteli Lipoprotein Kolesterol Oranı Stabil Anjina Pektorisi Olan Hastalarda Safen Ven Greft Açıklığını Öngördürebilir mi?

Öz:

Introduction: Circulating monocyte count is a predictive factor of new atherosclerotic plaque development. In addition, there is a strong inverse relationship between high-density lipoprotein (HDL) cholesterol and atherosclerosis. It has been shown that the monocyte/HDL cholesterol ratio (MHR) is a novel inflammatory marker. We aimed to investigate the relationship between MHR and saphenous vein graft disease (SVGD).Patients and Methods: A total of 3 69 patients were divided into 3 groups (positive SVGD group= 150, negative SVGD group= 89, normal coronary artery group= 130). Baseline characteristics and laboratory parameters were recorded and compared among the groups. Results: There were no significant differences between the positive and negative SVGD groups, except for age of SVG and left ventricular ejection fraction, according to baseline characteristics. C-reactive protein (CRP) levels, fasting blood glucose levels and mean platelet volume were higher in the positive SVGD group than in the negative SVGD group (p= 0.008, 0.048 and 0.042, respectively). MHR was not significantly different between the positive and negative SVGD groups (p= 0.169) and normal coronary artery group (p= 0.364). CRP was found to be an independent predictor factor of SVGD.Conclusion: There was no association between MHR and coronary atherosclerosis. MHR was not a predictive factor of SVGD.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ALSANCAK Y, ALİ S, sivri s, BİÇER H, SİVRİ H, YAŞAR A, BİLGE M (2017). Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. , 7 - 12.
Chicago	ALSANCAK Yakup,ALİ Sina,sivri serkan,BİÇER Hasan,SİVRİ Hatice Duygu Çiftçi,YAŞAR Ayşe Saatcı,BİLGE Mehmet Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. (2017): 7 - 12.
MLA	ALSANCAK Yakup,ALİ Sina,sivri serkan,BİÇER Hasan,SİVRİ Hatice Duygu Çiftçi,YAŞAR Ayşe Saatcı,BİLGE Mehmet Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. , 2017, ss.7 - 12.
AMA	ALSANCAK Y,ALİ S,sivri s,BİÇER H,SİVRİ H,YAŞAR A,BİLGE M Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. . 2017; 7 - 12.
Vancouver	ALSANCAK Y,ALİ S,sivri s,BİÇER H,SİVRİ H,YAŞAR A,BİLGE M Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. . 2017; 7 - 12.
IEEE	ALSANCAK Y,ALİ S,sivri s,BİÇER H,SİVRİ H,YAŞAR A,BİLGE M "Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?." , ss.7 - 12, 2017.
ISNAD	ALSANCAK, Yakup vd. "Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?". (2017), 7-12.

APA	ALSANCAK Y, ALİ S, sivri s, BİÇER H, SİVRİ H, YAŞAR A, BİLGE M (2017). Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. Koşuyolu Kalp Dergisi, 20(1), 7 - 12.
Chicago	ALSANCAK Yakup,ALİ Sina,sivri serkan,BİÇER Hasan,SİVRİ Hatice Duygu Çiftçi,YAŞAR Ayşe Saatcı,BİLGE Mehmet Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. Koşuyolu Kalp Dergisi 20, no.1 (2017): 7 - 12.
MLA	ALSANCAK Yakup,ALİ Sina,sivri serkan,BİÇER Hasan,SİVRİ Hatice Duygu Çiftçi,YAŞAR Ayşe Saatcı,BİLGE Mehmet Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. Koşuyolu Kalp Dergisi, vol.20, no.1, 2017, ss.7 - 12.
AMA	ALSANCAK Y,ALİ S,sivri s,BİÇER H,SİVRİ H,YAŞAR A,BİLGE M Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. Koşuyolu Kalp Dergisi. 2017; 20(1): 7 - 12.
Vancouver	ALSANCAK Y,ALİ S,sivri s,BİÇER H,SİVRİ H,YAŞAR A,BİLGE M Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?. Koşuyolu Kalp Dergisi. 2017; 20(1): 7 - 12.
IEEE	ALSANCAK Y,ALİ S,sivri s,BİÇER H,SİVRİ H,YAŞAR A,BİLGE M "Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?." Koşuyolu Kalp Dergisi, 20, ss.7 - 12, 2017.
ISNAD	ALSANCAK, Yakup vd. "Does Monocyte/High-Density Lipoprotein Cholesterol Ratio Predict Saphenous Vein Graft Patency in Patients with Stable Angina Pectoris?". Koşuyolu Kalp Dergisi 20/1 (2017), 7-12.