Yıl: 2016 Cilt: 46 Sayı: 2 Sayfa Aralığı: 343 - 348 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Fully automated morphological analysis of patients with obstructive sleep apnea

Öz:
Background/aim: Obstructive sleep apnea syndrome (OSAS) is a disease characterized by episodic hypoxia. We aimed to use the Freesurfer program for global evaluation of morphological changes in OSAS patients. Materials and methods: Three-dimensional T1-weighted images were obtained, and intracranial morphology was assessed in 18 patients with OSAS and 20 controls. Results of the volume and the cortical thickness analyses of both groups were compared statistically. Results: The total cortical, left right hemispheres gray matter (GM), corpus callosum, and total GM volumes were lower in OSAS patients when compared with the control group (P < 0.001). The average cortical thickness was lower in OSAS patients bilaterally in pars orbitalis, paracentral, rostral middle frontal, middle frontal, orbital, and superior frontal gyri when compared with the control group (P < 0.05). Furthermore, the volume and average cortical thickness of multiple anatomic regions, apart from the brain parts mentioned above, were decreased unilaterally (e.g., hippocampus, cingulum, putamen, thalamus) in OSAS patients (P < 0.05). Conclusion: Multiple morphologic changes occur in the cerebral structures of OSAS patients due to intermittent ischemia episodes. Detection of those areas with Freesurfer is easier. New studies with large series would be needed for these subjects.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ALGIN O, AKIN B, OCAKOGLU G, Ozmen E (2016). Fully automated morphological analysis of patients with obstructive sleep apnea. , 343 - 348.
Chicago ALGIN Oktay,AKIN Burak,OCAKOGLU Gokhan,Ozmen Evrim Fully automated morphological analysis of patients with obstructive sleep apnea. (2016): 343 - 348.
MLA ALGIN Oktay,AKIN Burak,OCAKOGLU Gokhan,Ozmen Evrim Fully automated morphological analysis of patients with obstructive sleep apnea. , 2016, ss.343 - 348.
AMA ALGIN O,AKIN B,OCAKOGLU G,Ozmen E Fully automated morphological analysis of patients with obstructive sleep apnea. . 2016; 343 - 348.
Vancouver ALGIN O,AKIN B,OCAKOGLU G,Ozmen E Fully automated morphological analysis of patients with obstructive sleep apnea. . 2016; 343 - 348.
IEEE ALGIN O,AKIN B,OCAKOGLU G,Ozmen E "Fully automated morphological analysis of patients with obstructive sleep apnea." , ss.343 - 348, 2016.
ISNAD ALGIN, Oktay vd. "Fully automated morphological analysis of patients with obstructive sleep apnea". (2016), 343-348.
APA ALGIN O, AKIN B, OCAKOGLU G, Ozmen E (2016). Fully automated morphological analysis of patients with obstructive sleep apnea. Turkish Journal of Medical Sciences, 46(2), 343 - 348.
Chicago ALGIN Oktay,AKIN Burak,OCAKOGLU Gokhan,Ozmen Evrim Fully automated morphological analysis of patients with obstructive sleep apnea. Turkish Journal of Medical Sciences 46, no.2 (2016): 343 - 348.
MLA ALGIN Oktay,AKIN Burak,OCAKOGLU Gokhan,Ozmen Evrim Fully automated morphological analysis of patients with obstructive sleep apnea. Turkish Journal of Medical Sciences, vol.46, no.2, 2016, ss.343 - 348.
AMA ALGIN O,AKIN B,OCAKOGLU G,Ozmen E Fully automated morphological analysis of patients with obstructive sleep apnea. Turkish Journal of Medical Sciences. 2016; 46(2): 343 - 348.
Vancouver ALGIN O,AKIN B,OCAKOGLU G,Ozmen E Fully automated morphological analysis of patients with obstructive sleep apnea. Turkish Journal of Medical Sciences. 2016; 46(2): 343 - 348.
IEEE ALGIN O,AKIN B,OCAKOGLU G,Ozmen E "Fully automated morphological analysis of patients with obstructive sleep apnea." Turkish Journal of Medical Sciences, 46, ss.343 - 348, 2016.
ISNAD ALGIN, Oktay vd. "Fully automated morphological analysis of patients with obstructive sleep apnea". Turkish Journal of Medical Sciences 46/2 (2016), 343-348.