Yıl: 2016 Cilt: 46 Sayı: 3 Sayfa Aralığı: 840 - 847 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study

Öz:
Background/aim:To determine the prevalence of malignancy in thyroid incidentalomas (TIs) detected by fluorine-18 fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT). Materials and methods: 18F-FDG PET/CT images were evaluated prospectively for the presence of thyroid uptake. The patients with a TI were evaluated by an endocrinologist according to the predefined diagnostic algorithm. The final diagnosis was obtained clinically and/or by pathology. Results: TI was detected in 4.2% of 4204 patients. A malignant thyroid nodule was diagnosed in 29% and 33% of the focal and diffusefocal uptake groups, respectively. However, no malignancy was detected in the diffuse uptake group. The standardized maximum uptake values (SUVmax) of the nodules were significantly higher in patients with thyroid malignancy than in patients with benign nodules (P = 0.006). The calculated cut-off value of SUVmax for malignancy was 3.5. In 2 patients in whom the cytopathological diagnosis was benign, malignancy was diagnosed after total thyroidectomy. Conclusion: A malignant nodule was present in one-third of the patients with focal or diffuse-focal uptake. A SUVmax value of 3.5 was considered as a cut-off value for the differentiation of a malignant lesion. Benign cytology in fine-needle aspiration biopsy for 2 patients underestimated a thyroid malignancy.
Anahtar Kelime:

Konular: Cerrahi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ŞENCAN EREN M, ÖZDOĞAN Ö, GEDİK A, CEYLAN M, GÜRAY DURAK M, SEÇİL M, KOÇDOR M, ÇÖMLEKÇİ A, DURAK H (2016). The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. , 840 - 847.
Chicago ŞENCAN EREN Mine,ÖZDOĞAN Özhan,GEDİK Arzu,CEYLAN Mehmet,GÜRAY DURAK Merih,SEÇİL Mustafa,KOÇDOR MEHMET ALI,ÇÖMLEKÇİ Abdurrahman,DURAK Hatice The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. (2016): 840 - 847.
MLA ŞENCAN EREN Mine,ÖZDOĞAN Özhan,GEDİK Arzu,CEYLAN Mehmet,GÜRAY DURAK Merih,SEÇİL Mustafa,KOÇDOR MEHMET ALI,ÇÖMLEKÇİ Abdurrahman,DURAK Hatice The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. , 2016, ss.840 - 847.
AMA ŞENCAN EREN M,ÖZDOĞAN Ö,GEDİK A,CEYLAN M,GÜRAY DURAK M,SEÇİL M,KOÇDOR M,ÇÖMLEKÇİ A,DURAK H The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. . 2016; 840 - 847.
Vancouver ŞENCAN EREN M,ÖZDOĞAN Ö,GEDİK A,CEYLAN M,GÜRAY DURAK M,SEÇİL M,KOÇDOR M,ÇÖMLEKÇİ A,DURAK H The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. . 2016; 840 - 847.
IEEE ŞENCAN EREN M,ÖZDOĞAN Ö,GEDİK A,CEYLAN M,GÜRAY DURAK M,SEÇİL M,KOÇDOR M,ÇÖMLEKÇİ A,DURAK H "The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study." , ss.840 - 847, 2016.
ISNAD ŞENCAN EREN, Mine vd. "The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study". (2016), 840-847.
APA ŞENCAN EREN M, ÖZDOĞAN Ö, GEDİK A, CEYLAN M, GÜRAY DURAK M, SEÇİL M, KOÇDOR M, ÇÖMLEKÇİ A, DURAK H (2016). The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. Turkish Journal of Medical Sciences, 46(3), 840 - 847.
Chicago ŞENCAN EREN Mine,ÖZDOĞAN Özhan,GEDİK Arzu,CEYLAN Mehmet,GÜRAY DURAK Merih,SEÇİL Mustafa,KOÇDOR MEHMET ALI,ÇÖMLEKÇİ Abdurrahman,DURAK Hatice The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. Turkish Journal of Medical Sciences 46, no.3 (2016): 840 - 847.
MLA ŞENCAN EREN Mine,ÖZDOĞAN Özhan,GEDİK Arzu,CEYLAN Mehmet,GÜRAY DURAK Merih,SEÇİL Mustafa,KOÇDOR MEHMET ALI,ÇÖMLEKÇİ Abdurrahman,DURAK Hatice The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. Turkish Journal of Medical Sciences, vol.46, no.3, 2016, ss.840 - 847.
AMA ŞENCAN EREN M,ÖZDOĞAN Ö,GEDİK A,CEYLAN M,GÜRAY DURAK M,SEÇİL M,KOÇDOR M,ÇÖMLEKÇİ A,DURAK H The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. Turkish Journal of Medical Sciences. 2016; 46(3): 840 - 847.
Vancouver ŞENCAN EREN M,ÖZDOĞAN Ö,GEDİK A,CEYLAN M,GÜRAY DURAK M,SEÇİL M,KOÇDOR M,ÇÖMLEKÇİ A,DURAK H The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study. Turkish Journal of Medical Sciences. 2016; 46(3): 840 - 847.
IEEE ŞENCAN EREN M,ÖZDOĞAN Ö,GEDİK A,CEYLAN M,GÜRAY DURAK M,SEÇİL M,KOÇDOR M,ÇÖMLEKÇİ A,DURAK H "The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study." Turkish Journal of Medical Sciences, 46, ss.840 - 847, 2016.
ISNAD ŞENCAN EREN, Mine vd. "The incidence of 18F-FDG PET/CT thyroid incidentalomas andthe prevalence of malignancy: a prospective study". Turkish Journal of Medical Sciences 46/3 (2016), 840-847.