Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency

Peynirci, Hande; Şahin, Ahmet Bilgehan; SARAYDAROĞLU, Özlem; Oz Gul, Ozen; SİSMAN, Pinar; Ersoy, Canan

Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency

Pinar SİSMAN, (Uludağ University)

Hande PEYNİRCİ, (Uludağ University)

Özlem SARAYDAROĞLU, (Uludağ University Faculty of Medicine, Department of Pathology, Bursa, Turkey)

Ahmet Bilgehan ŞAHİN, (Uludağ University Faculty of Medicine, Department of Internal Medicine, Bursa, Turkey)

Özen Öz GÜL, (Uludağ University)

Canan ERSOY (Uludağ University)

Turkish Journal of Endocrinology and Metabolism

18 2

Yıl: 2017 Cilt: 21 Sayı: 1 Sayfa Aralığı: 26 - 29 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency

Öz:

Tüberküloz, günümüzde, gelişmiş ülkelerde adrenal yetmezliğin sıklığı giderek azalan nedenlerinden biridir. Bu olgu sunumunda adrenal yetmezlik bulguları ile tanı alan adrenal ve miliyer akciğer tüberkülozlu hastayı sunmayı amaçladık. Yetmiş bir yaşında, daha önce tek taraflı adrenalektomi öyküsü olan kadın hasta adrenal yetmezlik semptomları ile başvurdu. Yapılan tetkiklerinde primer adrenal yetmezlik ve adrenal bezde tüberkülozun adrenal tutulumunu temsil eder nitelikte kitle saptandı. Her iki akciğerde miliyer tüberküloz ile uyumlu nodülleri mevcuttu. Anti-tüberküloz tedavi sonrası hastanın akciğerlerindeki nodüller kayboldu, adrenal kitle boyutlarında küçülme saptanmadı. Adrenalektomi yapılan hasta glukokortikoid ve mineralokortikoid tedavi ile takip edilmektedir. Adrenal tüberküloz gelişmekte olan ülkelerde halen adrenal yetmezliğin sık görülen nedenlerinden biridir. Tüberküloz adrenal bezde harabiyete neden olur ve özellikle adrenal bezde büyüme olan olgularda tanı güçtür

Anahtar Kelime:

Konular: Endokrinoloji ve Metabolizma

Adrenal Yetmezliğe Neden Olan Adrenal Kitle: Tüberküloz

Öz:

Tuberculosis, the prevalence of which has continued to decline in developed countries, is still one of the reasons of adrenal insufficiency. In this report, we aimed to present a case of adrenal and miliary tuberculosis presenting with adrenal insufficiency. A 71-year-old woman with a history of unilateral adrenalectomy was admitted with the symptoms of adrenal insufficiency. In her further medical investigations, the diagnosis of primary adrenal insufficiency was established and a mass presenting as involvement of tuberculosis was detected in the adrenal gland. Bilateral pulmonary nodules compatible with miliary tuberculosis were observed. After anti-tuberculosis treatment, pulmonary nodules disappeared, but there was no significant decrease in the size of the adrenal mass. The patient, who underwent adrenalectomy, was followed with glucocorticoid and mineralocorticoid treatment. Tuberculosis of the adrenal glands is a common cause of adrenal insufficiency in developing countries. Tuberculosis can destroy the adrenal glands and the diagnosis of adrenal tuberculosis, especially presenting with enlargement of the adrenal glands, can be difficult

Anahtar Kelime:

Konular: Endokrinoloji ve Metabolizma

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

1. Ersoy C. Akciğer ve Akciğer Dışı Organ Tüberkülozları. In: Özyardımcı N, editor. Akciğer ve Akciğer Dışı Organ Tüberkülozları: Uludağ Üniversitesi Basımevi; 2008.p.215-219.
2. Aron DC FJ, Tyrrell JB. Glucocorticoids and adrenal androgens. In: Gardner DG SD, editor. Basic and Clinical Endocrinology. 1. 8 ed. USA: The McGrawHill Companies; 2007.p.346-395.
3. Hieronimus S, Bernard JL, Chevallier P, Chevallier A, Chyderiotis G, Fenichel P, Landraud L. Adrenal tuberculosis after a pheochromocytoma: a misleading tumoral presentation. Ann Endocrinol (Paris). 2007;68:191-195.
4. Alevritis EM, Sarubbi FA, Jordan RM, Peiris AN. Infectious causes of adrenal insufficiency. South Med J. 2003;96:888-890.
5. Vita JA, Silverberg SJ, Goland RS, Austin JH, Knowlton AI. Clinical clues to the cause of Addison’s disease. Am J Med. 1985;78:461-466.
6. Kelestimur F, Unlu Y, Ozesmi M, Tolu I. A hormonal and radiological evaluation of adrenal gland in patients with acute or chronic pulmonary tuberculosis. Clin Endocrinol (Oxf). 1994;41:53-56.
7. Upadhyay J, Sudhindra P, Abraham G, Trivedi N. Tuberculosis of the adrenal gland: A case report and review of the literature of infections of the adrenal gland. Int J Endocrinol. 2014;2014:876037.
8. Sun ZH, Nomura K, Toraya S, Ujihara M, Horiba N, Suda T, Tsushima T, Demura H, Kono A. Clinical significance of adrenal computed tomography in Addison’s disease. Endocrinol Jpn. 1992;39:563-569.
9. Bhatia E, Jain SK, Gupta RK, Pandey R. Tuberculous Addison’s disease: Lack of normalization of adrenocortical function after anti-tuberculous chemotherapy. Clin Endocrinol (Oxf). 1998;48:355-359.
10. Penrice J, Nussey SS. Recovery of adrenal function following treatment of tuberculous Addison’s disease. Postgrad Med J. 1992;68:204-205.

APA	SİSMAN P, Peynirci H, SARAYDAROĞLU Ö, Şahin A, Oz Gul O, Ersoy C (2017). Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. , 26 - 29.
Chicago	SİSMAN Pinar,Peynirci Hande,SARAYDAROĞLU Özlem,Şahin Ahmet Bilgehan,Oz Gul Ozen,Ersoy Canan Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. (2017): 26 - 29.
MLA	SİSMAN Pinar,Peynirci Hande,SARAYDAROĞLU Özlem,Şahin Ahmet Bilgehan,Oz Gul Ozen,Ersoy Canan Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. , 2017, ss.26 - 29.
AMA	SİSMAN P,Peynirci H,SARAYDAROĞLU Ö,Şahin A,Oz Gul O,Ersoy C Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. . 2017; 26 - 29.
Vancouver	SİSMAN P,Peynirci H,SARAYDAROĞLU Ö,Şahin A,Oz Gul O,Ersoy C Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. . 2017; 26 - 29.
IEEE	SİSMAN P,Peynirci H,SARAYDAROĞLU Ö,Şahin A,Oz Gul O,Ersoy C "Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency." , ss.26 - 29, 2017.
ISNAD	SİSMAN, Pinar vd. "Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency". (2017), 26-29.

APA	SİSMAN P, Peynirci H, SARAYDAROĞLU Ö, Şahin A, Oz Gul O, Ersoy C (2017). Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. Turkish Journal of Endocrinology and Metabolism, 21(1), 26 - 29.
Chicago	SİSMAN Pinar,Peynirci Hande,SARAYDAROĞLU Özlem,Şahin Ahmet Bilgehan,Oz Gul Ozen,Ersoy Canan Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. Turkish Journal of Endocrinology and Metabolism 21, no.1 (2017): 26 - 29.
MLA	SİSMAN Pinar,Peynirci Hande,SARAYDAROĞLU Özlem,Şahin Ahmet Bilgehan,Oz Gul Ozen,Ersoy Canan Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. Turkish Journal of Endocrinology and Metabolism, vol.21, no.1, 2017, ss.26 - 29.
AMA	SİSMAN P,Peynirci H,SARAYDAROĞLU Ö,Şahin A,Oz Gul O,Ersoy C Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. Turkish Journal of Endocrinology and Metabolism. 2017; 21(1): 26 - 29.
Vancouver	SİSMAN P,Peynirci H,SARAYDAROĞLU Ö,Şahin A,Oz Gul O,Ersoy C Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency. Turkish Journal of Endocrinology and Metabolism. 2017; 21(1): 26 - 29.
IEEE	SİSMAN P,Peynirci H,SARAYDAROĞLU Ö,Şahin A,Oz Gul O,Ersoy C "Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency." Turkish Journal of Endocrinology and Metabolism, 21, ss.26 - 29, 2017.
ISNAD	SİSMAN, Pinar vd. "Tuberculosis A Case of Adrenal Mass Causing Adrenal Insufficiency". Turkish Journal of Endocrinology and Metabolism 21/1 (2017), 26-29.