Fournier's gangrene: Review of 120 patients and predictors of mortality

Ercan, Ilker; Isik, Ozgen; YILMAZLAR, AHMET TUNCAY; Ozer, Ali; Ozturk, Ersin; Gulcu, Baris

Fournier's gangrene: Review of 120 patients and predictors of mortality

AHMET TUNCAY YILMAZLAR, (Department of General Surgery, Uludag University Faculty of Medicine, Bursa)

Özgen IŞIK, (Department of General Surgery, Uludag University Faculty of Medicine, Bursa)

Ersin ÖZTÜRK, (Department of General Surgery, Uludag University Faculty of Medicine, Bursa)

Ali ÖZER, (Department of General Surgery, Uludag University Faculty of Medicine, Bursa)

Barış GÜLCÜ, (Department of General Surgery, Uludag University Faculty of Medicine, Bursa)

İlker ERCAN (Department of Biostatistics, Uludag University Faculty of Medicine, Bursa)

Ulusal Travma ve Acil Cerrahi Dergisi

1 1

Yıl: 2014 Cilt: 20 Sayı: 5 Sayfa Aralığı: 333 - 337 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Fournier's gangrene: Review of 120 patients and predictors of mortality

Öz:

AMAÇ: Fournier gangreni (FG) acil ve agresif debridman gerektiren, yıkıcı ve potansiyel ölümcül bir hastalıktır. Bu çalışmanın amacı FG için mortaliteprediktörlerini geniş bir kohortta araştırmaktır.GEREÇ VE YÖNTEM: Fournier gangreni hastalarının ileriye yönelik olarak kaydedilmiş verileri derlendi. Demografik veriler, semptom süresi, UludağFournier Gangreni Şiddet Skoru (UFGSI), yandaş hastalıklar [özellikle diabetes mellitus (DM)], etiyoloji, debridman sayısı, stoma gereksinimi, yoğunbakım ve hastane yatış süresi, morbidite ve mortalite oranları değerlendirildi. Multivaryans analiz ile mortaliteye etkili faktörler belirlendi.BULGULAR: Median yaşı 58 (22-85) olan 120 hasta (81 erkek) çalışmaya alındı. Median UFGSI skoru 9'du (1-30). Altmış dokuz hastada (%57.5) DMvardı. FG 59 hastada perianal, 52 hastada ürogenital ve 9 hastada cilt kaynaklıydı. Median debridman sayısı 3'tü (1-12) ve 31 hastada stoma açıldı, 48hasta yoğun bakımda takip edilirken 25 hastada mekanik ventilasyon desteği gerekti. Toplam mortalite oranı %20.8'di. Multivaryans analizde UFGSItek mortalite prediktörü olarak saptandı (p=0.001). UFGSI 9 veya daha yüksek olan hastalarda mortalite oranı 13.64 kez daha sıktı.TARTIŞMA: Fournier gangreni acil cerrahi gerektiren ölümcül bir hastalıktır. UFGSI FG hastalarında mortalitenin etkin bir prediktörüdür.

Anahtar Kelime:

Konular: Cerrahi

Fournier gangreni: 120 olgunun değerlendirmesi ve mortalite prediktörleri

Öz:

BACKGROUND: Fournier's gangrene (FG) is a devastating and potentially fatal disease requiring prompt and aggressive debridement. In this study, it was aimed to assess the predictors of mortality in a large cohort.METHODS: Prospectively maintained data of patients with FG were analyzed. Demographic data, duration of symptoms, Uludag Fournier's Gangrene Severity Index (UFGSI) scores, co-morbidities [particularly diabetes mellitus (DM)], etiologies, number of debridement, stoma requirements, length of intensive care unit and hospital stay, and morbidity and mortality rates were reviewed. Multivariate analysis was performed in order to determine factors affecting mortality.RESULTS: 120 patients (81 males) were included in the study. Median age was 58 years. UFGSI score was median 9 . DM was present in 69 (57.5%) patients. Etiology of FG was perianal in fifty-nine, urogenital in 52, and skin in 9 patients. Median debridement count was 3 . Thirty-one patients required stoma. Forty-eight patients were admitted to intensive care unit and 25 patients required mechanical ventilation. Overall mortality rate was 20.8%. Multivariate analysis revealed UFGSI as the only predictor of mortality (p=0.001). Mortality rate was 13.64 times higher for patients with a UFGSI score of 9 or higher.CONCLUSION: Fournier's gangrene is a mortal disease requiring emergency surgery. UFGSI is an efficient predictor of mortality for patients with FG

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	YILMAZLAR A, Isik O, Ozturk E, Ozer A, Gulcu B, Ercan I (2014). Fournier's gangrene: Review of 120 patients and predictors of mortality. , 333 - 337.
Chicago	YILMAZLAR AHMET TUNCAY,Isik Ozgen,Ozturk Ersin,Ozer Ali,Gulcu Baris,Ercan Ilker Fournier's gangrene: Review of 120 patients and predictors of mortality. (2014): 333 - 337.
MLA	YILMAZLAR AHMET TUNCAY,Isik Ozgen,Ozturk Ersin,Ozer Ali,Gulcu Baris,Ercan Ilker Fournier's gangrene: Review of 120 patients and predictors of mortality. , 2014, ss.333 - 337.
AMA	YILMAZLAR A,Isik O,Ozturk E,Ozer A,Gulcu B,Ercan I Fournier's gangrene: Review of 120 patients and predictors of mortality. . 2014; 333 - 337.
Vancouver	YILMAZLAR A,Isik O,Ozturk E,Ozer A,Gulcu B,Ercan I Fournier's gangrene: Review of 120 patients and predictors of mortality. . 2014; 333 - 337.
IEEE	YILMAZLAR A,Isik O,Ozturk E,Ozer A,Gulcu B,Ercan I "Fournier's gangrene: Review of 120 patients and predictors of mortality." , ss.333 - 337, 2014.
ISNAD	YILMAZLAR, AHMET TUNCAY vd. "Fournier's gangrene: Review of 120 patients and predictors of mortality". (2014), 333-337.

APA	YILMAZLAR A, Isik O, Ozturk E, Ozer A, Gulcu B, Ercan I (2014). Fournier's gangrene: Review of 120 patients and predictors of mortality. Ulusal Travma ve Acil Cerrahi Dergisi, 20(5), 333 - 337.
Chicago	YILMAZLAR AHMET TUNCAY,Isik Ozgen,Ozturk Ersin,Ozer Ali,Gulcu Baris,Ercan Ilker Fournier's gangrene: Review of 120 patients and predictors of mortality. Ulusal Travma ve Acil Cerrahi Dergisi 20, no.5 (2014): 333 - 337.
MLA	YILMAZLAR AHMET TUNCAY,Isik Ozgen,Ozturk Ersin,Ozer Ali,Gulcu Baris,Ercan Ilker Fournier's gangrene: Review of 120 patients and predictors of mortality. Ulusal Travma ve Acil Cerrahi Dergisi, vol.20, no.5, 2014, ss.333 - 337.
AMA	YILMAZLAR A,Isik O,Ozturk E,Ozer A,Gulcu B,Ercan I Fournier's gangrene: Review of 120 patients and predictors of mortality. Ulusal Travma ve Acil Cerrahi Dergisi. 2014; 20(5): 333 - 337.
Vancouver	YILMAZLAR A,Isik O,Ozturk E,Ozer A,Gulcu B,Ercan I Fournier's gangrene: Review of 120 patients and predictors of mortality. Ulusal Travma ve Acil Cerrahi Dergisi. 2014; 20(5): 333 - 337.
IEEE	YILMAZLAR A,Isik O,Ozturk E,Ozer A,Gulcu B,Ercan I "Fournier's gangrene: Review of 120 patients and predictors of mortality." Ulusal Travma ve Acil Cerrahi Dergisi, 20, ss.333 - 337, 2014.
ISNAD	YILMAZLAR, AHMET TUNCAY vd. "Fournier's gangrene: Review of 120 patients and predictors of mortality". Ulusal Travma ve Acil Cerrahi Dergisi 20/5 (2014), 333-337.