Yıl: 2014 Cilt: 38 Sayı: 3 Sayfa Aralığı: 141 - 146 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008

Öz:
Amaç: Bu çalışma, Uludağ Üniversitesi Tıp Fakültesi Tıbbi Mikrobiyoloji Anabilim Dalı ELISA laboratuvarına 72 aylık (Mart 2002 - Aralık 2008 tarihleri arasında) dönemde başvuran toksoplasmoz şüpheli hastalarda anti- Toxoplasma gondii IgG ve IgM antikorlarının dağılımını belirlemek amacıyla yapılmıştır. Yöntemler: Örnekler VIDAS (BioMérieux, France) IgG-avidite testi ve Fluorescent Enzyme-Linked Assay (ELFA) tekniği ile çalışılmıştır. Bulgular: Kadınlarda anti-T. gondii IgG ve IgM prevalansının (sırasıyla %29,2 ve %2,02) erkeklerdekinden (sırasıyla %21,2 ve %1,7) daha yüksek olduğu belirlenmiştir. Doğurgan dönemdeki kadınlarda anti-T. gondii IgG seroprevalansının %30,7 olduğu ve oranların %35,8 ile %27,4 arasında değiştiği izlenmiştir. IgG avidite testi çalışılmış doğurgan dönemdeki 166 kadının %81,9'unda yüksek, %10,2'sinde şüpheli sınırlar içinde, %7,9'unda düşük avidite değerlerine sahip olduğu saptanmıştır.Sonuç: Çalışma verileri ilimizin tamamını yansıtmamasına rağmen özellikle doğurgan dönemdeki seronegatif kadınlar, gebe kadınlar ve immünkompromize hastalar gibi risk gruplarında toksoplazmozun gözardı edilmemesi gerektiği düşünülmüştür
Anahtar Kelime:

Konular: Genel ve Dahili Tıp Parazitoloji

Uludağ Üniversitesi Hastanesi ELISA Laboratuvarına 2002-2008 Yılları Arasında Toxoplasmosis Şüphesi ile Başvuran Hastaların Serolojik Sonuçlarının Değerlendirilmesi

Öz:
Objective: The aim of this study is to investigate the distribution of anti-Toxoplasma gondii IgG and IgM antibodies in patients with suspected toxoplasmosis referred to the Uludağ University Medical School, Department of Medical Microbiology Enzyme-Linked Immunosorbent Assay (ELISA) laboratory over a 72-month period (March 2002-December 2008). Methods: The samples were analyzed using VIDAS (BioMérieux, France) IgG-avidity tests and the fluorescent enzyme-linked assay (ELFA) technique. Results: Results showed that the prevalence of anti-T. gondii IgG and IgM among women (29.2% and 2.02%, respectively) was higher than that of men (21.2% and 1.7%, respectively). The seroprevalence of anti-T. gondii IgG was 30.7% in childbearing-aged women, with rates ranging from 35.8% and 27.4% over the years. Avidity was found to be high, borderline, and lower (81.9%, 10.2%, and 7.9%, respectively) in the fertile age group of 166 women receiving the IgG avidity test. Conclusion: Although the study data may not reflect our entire province, it virtually turns out that the risk of toxoplasmosis must be seriously taken into account, particularly when approaching some risk groups, such as seronegative women of fertile age, pregnant women, and immunocompromised patients
Anahtar Kelime:

Konular: Genel ve Dahili Tıp Parazitoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA ALVER O, Göral G, Ercan I (2014). Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. , 141 - 146.
Chicago ALVER Oktay,Göral Güher,Ercan Ilker Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. (2014): 141 - 146.
MLA ALVER Oktay,Göral Güher,Ercan Ilker Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. , 2014, ss.141 - 146.
AMA ALVER O,Göral G,Ercan I Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. . 2014; 141 - 146.
Vancouver ALVER O,Göral G,Ercan I Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. . 2014; 141 - 146.
IEEE ALVER O,Göral G,Ercan I "Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008." , ss.141 - 146, 2014.
ISNAD ALVER, Oktay vd. "Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008". (2014), 141-146.
APA ALVER O, Göral G, Ercan I (2014). Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. Türkiye Parazitoloji Dergisi, 38(3), 141 - 146.
Chicago ALVER Oktay,Göral Güher,Ercan Ilker Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. Türkiye Parazitoloji Dergisi 38, no.3 (2014): 141 - 146.
MLA ALVER Oktay,Göral Güher,Ercan Ilker Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. Türkiye Parazitoloji Dergisi, vol.38, no.3, 2014, ss.141 - 146.
AMA ALVER O,Göral G,Ercan I Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. Türkiye Parazitoloji Dergisi. 2014; 38(3): 141 - 146.
Vancouver ALVER O,Göral G,Ercan I Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008. Türkiye Parazitoloji Dergisi. 2014; 38(3): 141 - 146.
IEEE ALVER O,Göral G,Ercan I "Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008." Türkiye Parazitoloji Dergisi, 38, ss.141 - 146, 2014.
ISNAD ALVER, Oktay vd. "Investigation of Serological Results of Patients with Suspected Toxoplasmosis Admitted to the ELISA Laboratory of Uludağ University Hospital between 2002-2008". Türkiye Parazitoloji Dergisi 38/3 (2014), 141-146.