Yıl: 2017 Cilt: 32 Sayı: 3 Sayfa Aralığı: 106 - 115 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique

Öz:
The aim of this study was to show that the optimum dosage can be delivered to the target organs at risk (OAR) by radiotherapy, which becomes more complicated because of technical difficulties arising from irregular, convex, and complex geometrical structure of the target, such as scalp irradiation, and because of situations resulting from the necessity of bolus of the lesion and immobilization as well as the proximity to neighboring critical organs using the VMAT-SIB technique. METHODSFive different VMAT-SIB schemes were designed using the Varian Trilogy IX linear accelerator (Varian Medical Systems) for total scalp irradiation and bilateral neck irradiation. These different VMAT scehemes were compared with respect to a dose volume histogram of obtained data, homogeneity, indices, conformity index, OAR, and doses of target volumes.RESULTSThe patient-designed bolus plan 1 with two isocenters was chosen as the most appropriate plan. Plans 2, 3, 4, and 5 were inappropriate plans because the application of the virtual bolus in plan 2 was difficult, plan 3 with one isocenter was unacceptable with respect to the value of conformity index, plan 4 with three isocenters had a matching field, and plan 5 in which different priority values were used had an increase in OAR doses.CONCLUSIONVMAT-SIB can be preferred as an appropriate radiotherapy technique as it can provide optimum and allowable OAR doses in tumors requiring an intensive treatment planning effort.
Anahtar Kelime:

Konular: Onkoloji
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Ito E, Nakamura M, Watanabe S and Morita A. Survival Analysis of Scalp Angiosarcoma Patients for Treatment Modalities in our Hospital Over the Past 28 Years. J Clin Exp Dermatol Res 2014;5(1):1-3.
  • 2. Wanebo HJ, Koness RJ, MacFarlane JK, Eilber FR, Byers RM, Elias EG, et al. Head and neck sarcoma: report of the Head and Neck Sarcoma Registry. Society of Head and Neck Surgeons Committee on Research. Head Neck 1992;14(1):1-7.
  • 3. Freedman AM, Reiman HM, Woods JE. Soft-tissue sarcomas of the head and neck. Am J Surg 1989;158(4):367- 72.
  • 4. Espat NJ, Lewis JJ, Woodruff JM, Antonescu C, Xia J, Leung D, et al. Confirmed angiosarcoma: prognostic factors and outcome in 50 prospectively followed patients. Sarcoma 2000;4(4):173-7.
  • 5. Bardwil JM, Mocega EE, Butler JJ, Russin DJ. Angiosarcomas of the head and neck region. Am J Surg 1968;116(4):548-53.
  • 6. Rice S, Kozak KR and Mohindra P. Scalp angiosarcoma: Discussion of a management plan. Applied Radiation Oncology 2013:20-3.
  • 7. Albores-Saavedra J, Schwartz AM, Henson DE, Kostun L, Hart A, Angeles-Albores D, et al. Cutaneous angiosarcoma. Analysis of 434 cases from the Surveillance, Epidemiology, and End Results Program, 1973-2007. Ann Diagn Pathol 2011;15(2):93-7.
  • 8. ICRU Report 50. Prescribing, recording, and reporting photon beam therapy. Bethesda; 1993.
  • 9. ICRU Report 62. Prescribing, recording and reporting photon beam therapy (supplement to ICRU report 50).Bethesda; 1999.
  • 10.Hu J, Xiao W, He Z, Kang D, Chen A, Qi Z. Target splitting non-coplanar RapidArc radiation therapy for a diffuse sebaceous carcinoma of the scalp: a novel delivery technique. Radiat Oncol 2014;9:204.
  • 11.Kelly PJ, Mannarino E, Lewis JH, Baldini EH, Hacker FL. Total dural irradiation: RapidArc versus static-field IMRT: a case study. Med Dosim 2012;37(2):175-81.
  • 12. Feuvret L, Noël G, Mazeron JJ, Bey P. Conformity index: a review. Int J Radiat Oncol Biol Phys 2006;64(2):333-42.
  • 13. Lomax NJ, Scheib SG. Quantifying the degree of conformity in radiosurgery treatment planning. Int J Radiat Oncol Biol Phys 2003;55(5):1409-19.
  • 14.Onay Ö, Ünal Karabey A, Morgül Y, Karabey MS. A comparative planning study of step -and -shoot IMRT versus helical tomotherapy IMRT in the treatment of craniospinal tumor. Turk J Oncol 2014;29(2):46-52.
  • 15.Nutting CM, Convery DJ, Cosgrove VP, Rowbottom C, Padhani AR, Webb S, et al. Reduction of small and large bowel irradiation using an optimized intensitymodulated pelvic radiotherapy technique in patients with prostate cancer. Int J Radiat Oncol Biol Phys 2000;48(3):649-56.
  • 16.Dushko L, Krstevska V, Petkovska S. A treatment planning comparison of two different 3d conformal techniques for irradiation of head and neck cancer patients. Procedings of the 2nd Conference on Medical Physics and Biomedical Engineering; 2010. p. 44.
  • 17.Maddox JC, Evans HL. Angiosarcoma of skin and soft tissue: a study of forty-four cases. Cancer 1981;48(8):1907-21.
  • 18.Pawlik TM, Paulino AF, McGinn CJ, Baker LH, Cohen DS, Morris JS, et al. Cutaneous angiosarcoma of the scalp: a multidisciplinary approach. Cancer 2003;98(8):1716-26.
  • 19.Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ. Angiosarcoma. Lancet Oncol 2010;11(10):983-91.
  • 20.Naka N, Ohsawa M, Tomita Y, Kanno H, Uchida A, Myoui A, et al. Prognostic factors in angiosarcoma: a multivariate analysis of 55 cases. J Surg Oncol 1996;61(3):170-6.
  • 21. Lydiatt WM, Shaha AR, Shah JP. Angiosarcoma of thehead and neck. Am J Surg 1994;168(5):451-4.
  • 22.Mark RJ, Poen JC, Tran LM, Fu YS, Juillard GF. Angiosarcoma. A report of 67 patients and a review of the literature. Cancer 1996;77(11):2400-6.
  • 23. Fujisawa Y, Yoshino K, Kadono T, Miyagawa T, Nakamura Y, Fujimoto M. Chemoradiotherapy with taxane is superior to conventional surgery and radiotherapy in the management of cutaneous angiosarcoma: a multicentre, retrospective study. Br J Dermatol 2014;171(6):1493-500.
  • 24.Miki Y, Tada T, Kamo R, Hosono MN, Tamiya H, Shimatani Y, et al. Single institutional experience of the treatment of angiosarcoma of the face and scalp. Br JRadiol 2013;86(1030):20130439.
  • 25. Lyseng-Williamson KA, Fenton C. Docetaxel: a review of its use in metastatic breast cancer. Drugs 2005;65(17):2513-31.
  • 26.Eisenhauer EA, Vermorken JB. The taxoids. Comparative clinical pharmacology and therapeutic potential. Drugs 1998;55(1):5-30.
  • 27. Fata F, O'Reilly E, Ilson D, Pfister D, Leffel D, Kelsen DP, et al. Paclitaxel in the treatment of patients with angiosarcoma of the scalp or face. Cancer 1999;86(10):2034-7.
  • 28.Fuller CK, Charlson JA, Dankle SK, Russell TJ. Dramatic improvement of inoperable angiosarcoma with combination paclitaxel and bevacizumab chemotherapy. J Am Acad Dermatol 2010;63(4):e83-4.
  • 29.Mendenhall WM, Mendenhall CM, Werning JW, Reith JD, Mendenhall NP. Cutaneous angiosarcoma. Am J Clin Oncol 2006;29(5):524-8.
  • 30.Mathew P, Vakar-Lopez F, Troncoso P. Protracted remission of metastatic epithelioid angiosarcoma with weekly infusion of doxorubicin, paclitaxel, and cisplatin. Lancet Oncol 2006;7(1):92-3.
  • 31.Eiling S, Lischner S, Busch JO, Rothaupt D, Christophers E, Hauschild A. Complete remission of a radio-resistant cutaneous angiosarcoma of the scalp by systemic treatment with liposomal doxorubicin. Br J Dermatol 2002;147(1):150-3.
  • 32. Verdier E, Carvalho P, Young P, Musette P, Courville P, Joly P. Lymphangiosarcoma treated with liposomal doxorubicin (Caelyx). Ann Dermatol Venereol 2007;134(10 Pt 1):760-3.
  • 33.Verweij J, Lee SM, Ruka W, Buesa J, Coleman R, van Hoessel R, et al. Randomized phase II study of docetaxel versus doxorubicin in first- and second-line chemotherapy for locally advanced or metastatic soft tissue sarcomas in adults: a study of the european organization for research and treatment of cancer soft tissue and bone sarcoma group. J Clin Oncol 2000;18(10):2081-6.
  • 34.Ye J, Li XF, Wang YD, Yuan Y. Long-term survival of a patient with scalp angiosarcoma and multiple metastases treated using combination therapy: A case report. Oncol Lett 2015;9(4):1725-8.
  • 35.Patel SH, Hayden RE, Hinni ML, Wong WW, Foote RL, Milani S, et al. Angiosarcoma of the scalp and face: the Mayo Clinic experience. JAMA Otolaryngol Head Neck Surg 2015;141(4):335-40.
  • 36. Sasaki R, Soejima T, Kishi K, Imajo Y, Hirota S, Kamikonya N, et al. Angiosarcoma treated with radiotherapy: impact of tumor type and size on outcome. Int J Radiat Oncol Biol Phys 2002;52(4):1032-40.
  • 37.Guadagnolo BA, Zagars GK, Araujo D, Ravi V, Shellenberger TD, Sturgis EM. Outcomes after definitive treatment for cutaneous angiosarcoma of the face and scalp. Head Neck 2011;33(5):661-7.
  • 38.Mellenberg DE, Schoeppel SL. Total scalp treatment of mycosis fungoides: the 4 x 4 technique. Int J Radiat Oncol Biol Phys 1993;27(4):953-8.
  • 39.Able CM, Mills MD, McNeese MD, Hogstrom KR. Evaluation of a total scalp electron irradiation technique. Int J Radiat Oncol Biol Phys 1991;21(4):1063-72.
  • 40. Sagar SM, Pujara CM. Radical treatment of angiosarcoma of the scalp using megavoltage electron beam therapy. Br J Radiol 1992;65(773):421-4.
  • 41.Akazawa C. Treatment of the scalp using photon and electron beams. Med Dosim 1989;14(2):129-31.
  • 42.Bedford JL, Childs PJ, Hansen VN, Warrington AP, Mendes RL, Glees JP. Treatment of extensive scalp lesions with segmental intensity-modulated photon therapy. Int J Radiat Oncol Biol Phys 2005;62(5):1549-58.
  • 43.Chan MF, Song Y, Burman C, Chui CS, Schupak K. The treatment of extensive scalp lesions combining electrons with intensity-modulated photons. Conf Proc IEEE Eng Med Biol Soc 2006;1:152-5.
  • 44. Samant RS, Fox GW, Gerig LH, Montgomery LA, Allan DS. Total scalp radiation using image-guided IMRT for progressive cutaneous T cell lymphoma. Br J Radiol 2009;82(978):e122-5.
  • 45.Wojcicka JB, Lasher DE, McAfee SS, Fortier GA. Dosimetric comparison of three different treatment techniques in extensive scalp lesion irradiation. Radiother Oncol 2009;91(2):255-60.
  • 46.Tung SS, Shiu AS, Starkschall G, Morrison WH, Hogstrom KR. Dosimetric evaluation of total scalp irradiation using a lateral electron-photon technique. Int J Radiat Oncol Biol Phys 1993;27(1):153-60.
  • 47.Locke J, Low DA, Grigireit T, Chao KS. Potential of tomotherapy for total scalp treatment. Int J Radiat Oncol Biol Phys 2002;52(2):553-9.
  • 48.Wang BH, Hua W, Gu X, Wang XL, Li J, Liu LQ, et al. Dosimetric study of different radiotherapy planning approaches for hippocampal avoidance whole-brain radiation therapy (HA-WBRT) based on fused CT and MRI imaging. Australas Phys Eng Sci Med 2015;38(4):767- 75.
  • 49. Song JH, Jung JY, Park HW, Lee GW, Chae SM, Kay CS, et al. Dosimetric comparison of three different treatment modalities for total scalp irradiation: the conventional lateral photon-electron technique, helical tomotherapy, and volumetric-modulated arc therapy. JRadiat Res 2015;56(4):717-26.
  • 50.Ostheimer C, Hübsch P, Janich M, Gerlach R, Vordermark D. Dosimetric comparison of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) in total scalp irradiation: a single institutional experience. Radiat Oncol J 2016;34(4):313-21.
APA Yılmaz Rakıcı S, ÇINAR Y, Eren M (2017). Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. , 106 - 115.
Chicago Yılmaz Rakıcı Sema,ÇINAR Yunus,Eren Mehmet Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. (2017): 106 - 115.
MLA Yılmaz Rakıcı Sema,ÇINAR Yunus,Eren Mehmet Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. , 2017, ss.106 - 115.
AMA Yılmaz Rakıcı S,ÇINAR Y,Eren M Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. . 2017; 106 - 115.
Vancouver Yılmaz Rakıcı S,ÇINAR Y,Eren M Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. . 2017; 106 - 115.
IEEE Yılmaz Rakıcı S,ÇINAR Y,Eren M "Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique." , ss.106 - 115, 2017.
ISNAD Yılmaz Rakıcı, Sema vd. "Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique". (2017), 106-115.
APA Yılmaz Rakıcı S, ÇINAR Y, Eren M (2017). Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. Türk Onkoloji Dergisi, 32(3), 106 - 115.
Chicago Yılmaz Rakıcı Sema,ÇINAR Yunus,Eren Mehmet Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. Türk Onkoloji Dergisi 32, no.3 (2017): 106 - 115.
MLA Yılmaz Rakıcı Sema,ÇINAR Yunus,Eren Mehmet Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. Türk Onkoloji Dergisi, vol.32, no.3, 2017, ss.106 - 115.
AMA Yılmaz Rakıcı S,ÇINAR Y,Eren M Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. Türk Onkoloji Dergisi. 2017; 32(3): 106 - 115.
Vancouver Yılmaz Rakıcı S,ÇINAR Y,Eren M Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique. Türk Onkoloji Dergisi. 2017; 32(3): 106 - 115.
IEEE Yılmaz Rakıcı S,ÇINAR Y,Eren M "Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique." Türk Onkoloji Dergisi, 32, ss.106 - 115, 2017.
ISNAD Yılmaz Rakıcı, Sema vd. "Total Scalp Irradiation: The Comparison of Five Different Plans Using Volumetric Modulated Arc Therapy- Simultaneous Integrated Boost (VMAT-SIB) Technique". Türk Onkoloji Dergisi 32/3 (2017), 106-115.