Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis
Yıl: 2017 Cilt: 34 Sayı: 3 Sayfa Aralığı: 207 - 214 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022
Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis
Öz: Amaclar: Tek lif EMG miyastenia gravis (MG)'li hastaların tanısında kullanılmaktadır, repetitif sinir stimulasyonuna kıyasla daha ay spesifik olmasına ragmen daha duyarlıdir. Gectiğimiz iki dekad boyunca konsantrik igne elektodlari (CN) jitter hesaplanmasında kullanılmıştır. Bu retrospektif çalışmada, MG hastalarında CN-jitterin duyarlılığını ortaya koymayı hedefledik. Yontem: Noromüsküler klinigimizde izlenen MG tanılı hastalar çalışmaya dahil edildi. Klinik bulgular ve CN-jitter analizleri retrospektif olarak analiz edildi. Sonuçlar: Nöromüskuler kliniğimize başvuran MG tanılı 401 hastanın arasında 155'i elektrofizyolojik olarak incelendi. Aralarında 136 hastaya CN jitter analizi yapıldı. Hastaların % 84'ünün yüksek jitteri vardı. CN jitter duyarlılığı bir kas çalışıldiğinda % 80 bulundu, iki kas çalışıldığında ise duyarlılık % 90'a yükseldi. Okuler MG'de (OMG) ve jeneralize MG'de (GMG) CN-jitter in duyarlılığı sırasıyla % 81 ve % 86 idi. Musk -AB pozitif hastaların CNjitter pozitivitesi en yüksekti (% 92), bunu AchR-ab pozitif (% 86) ve seronegatif (% 75) hastalar izliyordu. GMG'li 26 hastanın 25'inde ekstensör digitorum kommunis kasında pozitif CN-jitteri bulundu. Sonuçlar: CN-jitteri MG'li hastalarda duyarlı bir yöntemdir. Duyarlılık iki kas çalışıldığında artmaktadır
Anahtar Kelime: Konular:
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Öz: Objectives: Single-fiber electromyography is being used in the diagnosis of patients with myasthenia gravis (MG) and is more sensitive, although less specific, than repetitive nerve stimulation (RNS). For the past two decades, concentric needle electrodes (CN) have been used in calculating jitter. In this retrospective study, we aimed to reveal the sensitivity of CNjitter in patients with MG. Methods: Patients with MG who were followed up in our neuromuscular clinic were recruited to the study. Clinical findings and CN-jitter analyses were reviewed retrospectively. Results: Among the 401 patients with MG who were admitted to our neuromuscular clinic, 155 patients were investigated electrophysiologically. Among them, 136 patients underwent CN-jitter analysis. Eighty-four percent of the patients had high jitter. The sensitivity of CNjitter was 80% when only one muscle was studied, whereas the sensitivity rose to 90% when two muscles were studied. The sensitivity of CN-jitter in ocular MG (OMG) and generalized MG (GMG) was 81% and 86%, respectively. MuSK-ab positive patients tended to have the highest positivity in CN-jitter (92%), followed by AChR-ab positive (86%) and seronegative patients (75%). Twenty-five of 26 patients with GMG had positive CN-jitter in the extensor digitorum communis (ED) muscle. Conclusion: CN-jitter is a sensitive method in patients with MG. Sensitivity improved when two muscles were studied
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ŞİRİN İNAN N, ORHAN E, Durmus H, OFLAZER P, parman y, ÖGE A, deymeer f, BASLO M (2017). Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. , 207 - 214. |
| Chicago | ŞİRİN İNAN NERMİN GÖRKEM,ORHAN Elif Kocasoy,Durmus Hacer,OFLAZER Piraye,parman yesim,ÖGE Ali Emre,deymeer feza,BASLO Mehmet Barış Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. (2017): 207 - 214. |
| MLA | ŞİRİN İNAN NERMİN GÖRKEM,ORHAN Elif Kocasoy,Durmus Hacer,OFLAZER Piraye,parman yesim,ÖGE Ali Emre,deymeer feza,BASLO Mehmet Barış Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. , 2017, ss.207 - 214. |
| AMA | ŞİRİN İNAN N,ORHAN E,Durmus H,OFLAZER P,parman y,ÖGE A,deymeer f,BASLO M Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. . 2017; 207 - 214. |
| Vancouver | ŞİRİN İNAN N,ORHAN E,Durmus H,OFLAZER P,parman y,ÖGE A,deymeer f,BASLO M Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. . 2017; 207 - 214. |
| IEEE | ŞİRİN İNAN N,ORHAN E,Durmus H,OFLAZER P,parman y,ÖGE A,deymeer f,BASLO M "Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis." , ss.207 - 214, 2017. |
| ISNAD | ŞİRİN İNAN, NERMİN GÖRKEM vd. "Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis". (2017), 207-214. |
| APA | ŞİRİN İNAN N, ORHAN E, Durmus H, OFLAZER P, parman y, ÖGE A, deymeer f, BASLO M (2017). Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. Journal of Neurological Sciences (Turkish), 34(3), 207 - 214. |
| Chicago | ŞİRİN İNAN NERMİN GÖRKEM,ORHAN Elif Kocasoy,Durmus Hacer,OFLAZER Piraye,parman yesim,ÖGE Ali Emre,deymeer feza,BASLO Mehmet Barış Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. Journal of Neurological Sciences (Turkish) 34, no.3 (2017): 207 - 214. |
| MLA | ŞİRİN İNAN NERMİN GÖRKEM,ORHAN Elif Kocasoy,Durmus Hacer,OFLAZER Piraye,parman yesim,ÖGE Ali Emre,deymeer feza,BASLO Mehmet Barış Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. Journal of Neurological Sciences (Turkish), vol.34, no.3, 2017, ss.207 - 214. |
| AMA | ŞİRİN İNAN N,ORHAN E,Durmus H,OFLAZER P,parman y,ÖGE A,deymeer f,BASLO M Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. Journal of Neurological Sciences (Turkish). 2017; 34(3): 207 - 214. |
| Vancouver | ŞİRİN İNAN N,ORHAN E,Durmus H,OFLAZER P,parman y,ÖGE A,deymeer f,BASLO M Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis. Journal of Neurological Sciences (Turkish). 2017; 34(3): 207 - 214. |
| IEEE | ŞİRİN İNAN N,ORHAN E,Durmus H,OFLAZER P,parman y,ÖGE A,deymeer f,BASLO M "Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis." Journal of Neurological Sciences (Turkish), 34, ss.207 - 214, 2017. |
| ISNAD | ŞİRİN İNAN, NERMİN GÖRKEM vd. "Jitter Measurement using a Concentric Needle in 133 Patients with Myasthenia Gravis: A Retrospective Analysis". Journal of Neurological Sciences (Turkish) 34/3 (2017), 207-214. |
