Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma

YAZGAN AKSOY, Duygu; yetisir, fahri; KILIÇ, Mehmet; BAYRAKTAR, Miyase; Akın, Şafak; Akin, Serkan

Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma

Şafak AKIN, (Hacettepe Üniversitesi, Tıp Fakültesi, Endokrinoloji ve Metabolizma Anabilim Dalı, Ankara, Türkiye)

Duygu YAZGAN AKSOY, (Acıbadem Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, İstanbul, Türkiye)

Serkan AKIN, (Hacettepe Üniversitesi, Tıp Fakültesi, Tıbbi Onkoloji Anabilim Dalı, Ankara, Türkiye)

Mehmet KILIÇ, (Yıldırım Beyazıt Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Ankara, Türkiye)

Fahri YETİŞİR, (Ankara Medicana Hastanesi, Genel Cerrahi Kliniği, Ankara, Türkiye)

Miyase BAYRAKTAR (Hacettepe Üniversitesi, Tıp Fakültesi, Endokrinoloji ve Metabolizma Anabilim Dalı, Ankara, Türkiye)

Turkish Journal of Medical Sciences

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Yıl: 2017 Cilt: 47 Sayı: 6 Sayfa Aralığı: 1723 - 1727 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma

Öz:

Background/aim: The purpose of this study was to analyze the clinicopathological characteristics of patients with papillary thyroid carcinoma (PTC) and papillary thyroid microcarcinoma (PTMC) and predictive factors for central lymph node metastasis (CLNM). Materials and methods: Patients diagnosed as having PTC and PTMC were evaluated. Clinical and laboratory parameters were recorded. Results: The mean age at diagnosis was 47.3 ± 11.9 years. Of all 223 patients, 91 (40.8%) had lymph nodes removed, 29 of whom had lymph node metastasis and 24 of whom had only CLNM. Univariate analysis revealed that central lymph node metastasis was associated with male sex, presence of bilaterality, presence of extrathyroidal extension, and tumor size (P = 0.033, P = 0.027, P < 0.001, P < 0.001, respectively). However, multivariate logistic regression analysis showed that sex, age, tumor size, multifocality, bilaterality, extrathyroidal extension, clinical suspicion, and chronic lymphocytic thyroiditis were not significantly correlated with an increased risk for CLNM. Conclusion: Lymph node metastasis is known to be a significant predictor of locoregional recurrence in patients with PTC and PTMC. Further prospective studies are needed to identify the extent of surgery such as central lymph node dissection in patients with PTC or PTMC.

Anahtar Kelime:

Konular: Cerrahi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Akın Ş, YAZGAN AKSOY D, Akin S, KILIÇ M, yetisir f, BAYRAKTAR M (2017). Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. , 1723 - 1727.
Chicago	Akın Şafak,YAZGAN AKSOY Duygu,Akin Serkan,KILIÇ Mehmet,yetisir fahri,BAYRAKTAR Miyase Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. (2017): 1723 - 1727.
MLA	Akın Şafak,YAZGAN AKSOY Duygu,Akin Serkan,KILIÇ Mehmet,yetisir fahri,BAYRAKTAR Miyase Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. , 2017, ss.1723 - 1727.
AMA	Akın Ş,YAZGAN AKSOY D,Akin S,KILIÇ M,yetisir f,BAYRAKTAR M Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. . 2017; 1723 - 1727.
Vancouver	Akın Ş,YAZGAN AKSOY D,Akin S,KILIÇ M,yetisir f,BAYRAKTAR M Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. . 2017; 1723 - 1727.
IEEE	Akın Ş,YAZGAN AKSOY D,Akin S,KILIÇ M,yetisir f,BAYRAKTAR M "Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma." , ss.1723 - 1727, 2017.
ISNAD	Akın, Şafak vd. "Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma". (2017), 1723-1727.

APA	Akın Ş, YAZGAN AKSOY D, Akin S, KILIÇ M, yetisir f, BAYRAKTAR M (2017). Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. Turkish Journal of Medical Sciences, 47(6), 1723 - 1727.
Chicago	Akın Şafak,YAZGAN AKSOY Duygu,Akin Serkan,KILIÇ Mehmet,yetisir fahri,BAYRAKTAR Miyase Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. Turkish Journal of Medical Sciences 47, no.6 (2017): 1723 - 1727.
MLA	Akın Şafak,YAZGAN AKSOY Duygu,Akin Serkan,KILIÇ Mehmet,yetisir fahri,BAYRAKTAR Miyase Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. Turkish Journal of Medical Sciences, vol.47, no.6, 2017, ss.1723 - 1727.
AMA	Akın Ş,YAZGAN AKSOY D,Akin S,KILIÇ M,yetisir f,BAYRAKTAR M Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. Turkish Journal of Medical Sciences. 2017; 47(6): 1723 - 1727.
Vancouver	Akın Ş,YAZGAN AKSOY D,Akin S,KILIÇ M,yetisir f,BAYRAKTAR M Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma. Turkish Journal of Medical Sciences. 2017; 47(6): 1723 - 1727.
IEEE	Akın Ş,YAZGAN AKSOY D,Akin S,KILIÇ M,yetisir f,BAYRAKTAR M "Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma." Turkish Journal of Medical Sciences, 47, ss.1723 - 1727, 2017.
ISNAD	Akın, Şafak vd. "Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma". Turkish Journal of Medical Sciences 47/6 (2017), 1723-1727.