Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis

Aslan, Mehmet; toktas, Osman

Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis

OSMAN TOKTAŞ, (Yuzuncu Yil University, Medical Faculty, Department of General Surgery, Van, Turkey)

Mehmet ASLAN (Yuzuncu Yil University, Medical Faculty, Department of Internal Medicine, Van, Turkey)

Eastern Journal of Medicine

8 0

Yıl: 2017 Cilt: 22 Sayı: 1 Sayfa Aralığı: 5 - 9 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis

Öz:

Mean platelet volume (MPV), red cell distribution width (RDW), platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) have been seperately reported to be laboratory markers in several inflammatory diseases, including acute appendicitis. However, the results of these studies are conflicting. The aim of this study was to simultaneously investigate if MPV, RDW, PLR and NLR have a diagnostic role in the diagnosis of acute appendicitis and also the relationship between these systemic inflammation marker and leukocyte count. Thirty patients with acute appendicitis and 30 age-matched healthy subjects. RDW, MPV, neutrophils, lymphocytes and platelet counts were evaluated with complete blood count. The NLR and PLR were calculated as the ratios of the neutrophils and platelets to the lymphocytes. NLR and leukocyte count were significantly higher in the acute appendicitis patients compared to controls (both p<0.001), while RDW levels were significantly lower (p=0.041). There were no statistically significant differences regarding platelet numbers, MPV levels and PLR between acute appendicitis and healthy subjects (All; p>0.05). There was a significant correlation between leukocyte count and NLR (p<0.01, r=0.365). However, leukocyte count was not correlated with RDW and MPV levels (all; p>0.05). The current study is the first to investigate MPV, RDW, PLR and NLR in acute appendicitis patients. We found significantly increased NLR and leukocyte count in acute appendicitis patients compared to healthy subjects. Combined use of NLR and RDW values along with leukocyte count and other clinical assessment could help the diagnostic process of acute appendicitis.

Anahtar Kelime:

Konular: Diş Hekimliği Toksikoloji Farmakoloji ve Eczacılık

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	toktas O, Aslan M (2017). Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. , 5 - 9.
Chicago	toktas Osman,Aslan Mehmet Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. (2017): 5 - 9.
MLA	toktas Osman,Aslan Mehmet Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. , 2017, ss.5 - 9.
AMA	toktas O,Aslan M Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. . 2017; 5 - 9.
Vancouver	toktas O,Aslan M Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. . 2017; 5 - 9.
IEEE	toktas O,Aslan M "Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis." , ss.5 - 9, 2017.
ISNAD	toktas, Osman - Aslan, Mehmet. "Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis". (2017), 5-9.

APA	toktas O, Aslan M (2017). Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. Eastern Journal of Medicine, 22(1), 5 - 9.
Chicago	toktas Osman,Aslan Mehmet Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. Eastern Journal of Medicine 22, no.1 (2017): 5 - 9.
MLA	toktas Osman,Aslan Mehmet Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. Eastern Journal of Medicine, vol.22, no.1, 2017, ss.5 - 9.
AMA	toktas O,Aslan M Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. Eastern Journal of Medicine. 2017; 22(1): 5 - 9.
Vancouver	toktas O,Aslan M Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis. Eastern Journal of Medicine. 2017; 22(1): 5 - 9.
IEEE	toktas O,Aslan M "Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis." Eastern Journal of Medicine, 22, ss.5 - 9, 2017.
ISNAD	toktas, Osman - Aslan, Mehmet. "Mean platelet volume, red cell distribution width, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in the diagnosis of acute appendicitis". Eastern Journal of Medicine 22/1 (2017), 5-9.