Yıl: 2016 Cilt: 32 Sayı: 2 Sayfa Aralığı: 92 - 98 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması

Öz:
Prostat kanseri kansere bağlı ölümler arasında önemli bir yer tutmaktadır. Prostat kanseri tedavisinde brakiterapi uygulaması son 20 yıl içerisinde değer kazanmıştır. Prostat kanseri tedavisinde brakiterapi en az prostatektomi kadar etkin tedavi sonuçlarını daha az yan etki ile sağlar. Yüksek doz hızında (High dose rate: HDR) brakiterapi uygulaması genellikle eksternal radyoterapiye ek olarak boost amaçlı kullanılmakla birlikte, tek başına düşük doz hızında (Low dose rate: LDR) brakiterapiye alternatif olarak da kullanılabilir. HDR monoterapisi kısıtlı klinik deneyim nedeniyle kontrollü çalışmalar dışında kullanılmamaktadır. LDR brakiterapiden farklı olarak kapsül ve seminal vezikül invazyonu olan hastalarda HDR brakiterapi uygulanabilmektedir. Bu uygulama minimal invaziv bir prosedür sonrası hızlı bir iyileşme ile sonuçlanan ayaktan tedavi özelliğine sahiptir. Bununla birlikte, uzun dönem sekel ya da ciddi yan etki gelişme riski cerrahi yöntemlere göre daha azdır. Erektil disfonksiyon açısından da daha iyi bir korunma sağlar.
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel

High Dose Rate Brachytherapy Application in Prostate Cancer Treatment

Öz:
Prostate cancer is an important cause of cancer releateddeaths. Brachytherapy application in patients with prostatecancer has gained value increasingly in the last 20 years.Effective treatment outcomes with much lower side effects atleast as prostatectomy can be achieved with brachytherapy.Although high dose rate (HDR) brachytherapy applicationis used in addition to external radiotherapy as boost dose, itcan be used as monotherapy for an alternative to low doserate (LDR) brachyterapy.Nevertheless, due to limited clinicalexperience, HDR monotherapy is not recommendedexcept in controlled clinical trials. Differently from LDR,HDR brachytherapy can be used in patients with invasionof prostatic capsul and/or seminal vesicle.This applicationis a minimal invazive procedure and ambulatory treatmentresulting in a quick recovery. Development of long term sequelaeor serious side effects are lower than those of surgicalprocedures. At the same time it also provides a betterprotection in terms of erectile dysfunction.
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel
Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA ÖZEN A, PARLAR S, SAYNAK M, ÇALOĞLU H, UZAL M (2016). Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. , 92 - 98.
Chicago ÖZEN Alaattin,PARLAR SULE,SAYNAK Mert,ÇALOĞLU Hasan Murat,UZAL Mustafa Cem Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. (2016): 92 - 98.
MLA ÖZEN Alaattin,PARLAR SULE,SAYNAK Mert,ÇALOĞLU Hasan Murat,UZAL Mustafa Cem Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. , 2016, ss.92 - 98.
AMA ÖZEN A,PARLAR S,SAYNAK M,ÇALOĞLU H,UZAL M Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. . 2016; 92 - 98.
Vancouver ÖZEN A,PARLAR S,SAYNAK M,ÇALOĞLU H,UZAL M Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. . 2016; 92 - 98.
IEEE ÖZEN A,PARLAR S,SAYNAK M,ÇALOĞLU H,UZAL M "Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması." , ss.92 - 98, 2016.
ISNAD ÖZEN, Alaattin vd. "Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması". (2016), 92-98.
APA ÖZEN A, PARLAR S, SAYNAK M, ÇALOĞLU H, UZAL M (2016). Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. Okmeydanı Tıp Dergisi, 32(2), 92 - 98.
Chicago ÖZEN Alaattin,PARLAR SULE,SAYNAK Mert,ÇALOĞLU Hasan Murat,UZAL Mustafa Cem Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. Okmeydanı Tıp Dergisi 32, no.2 (2016): 92 - 98.
MLA ÖZEN Alaattin,PARLAR SULE,SAYNAK Mert,ÇALOĞLU Hasan Murat,UZAL Mustafa Cem Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. Okmeydanı Tıp Dergisi, vol.32, no.2, 2016, ss.92 - 98.
AMA ÖZEN A,PARLAR S,SAYNAK M,ÇALOĞLU H,UZAL M Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. Okmeydanı Tıp Dergisi. 2016; 32(2): 92 - 98.
Vancouver ÖZEN A,PARLAR S,SAYNAK M,ÇALOĞLU H,UZAL M Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması. Okmeydanı Tıp Dergisi. 2016; 32(2): 92 - 98.
IEEE ÖZEN A,PARLAR S,SAYNAK M,ÇALOĞLU H,UZAL M "Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması." Okmeydanı Tıp Dergisi, 32, ss.92 - 98, 2016.
ISNAD ÖZEN, Alaattin vd. "Prostat Kanseri Tedavisinde Yüksek Doz Hızında Brakiterapi Uygulaması". Okmeydanı Tıp Dergisi 32/2 (2016), 92-98.