Yıl: 2017 Cilt: 9 Sayı: 1 Sayfa Aralığı: 53 - 57 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus

Öz:
Amaç: Bu çalışmada, Verbascum thapsus L. (Scrophulariaceae) bitkisinin yapraklarından elde edilen etanol ekstraktının anti-Staphylococcal aktivitesinin araştırılması amaçlanmıştır. Yöntem: Verbascum thapsus L. (Scrophulariaceae) bitkisinin yapraklarından elde edilen etanol Staphylococcus aureus (MRSA) bakterilerine karşı Agar-kuyu difüzyon metodu ve mikrodilüsyon metodu ile araştırılmıştır. Bulgular: Etanol ekstraktı Methicillin-Dirençli Staphylococcus aureus (MRSA) bakterilerine karşı (MIC<1024 µg/mL) antibakteriyal bir aktivite göstermiştir. Methicillin ve Gentamicin antibiyotikleri ile karşılaştırıldığında, ekstraktın MRSA suşlarına karşı oldukça etkili olduğu saptanmıştır. Sonuç: Verbascum thapsus L. (Scrophulariaceae)'nin anti-Staphylococcal ajan olarak kullanılabilirliği in vitro olarak uygun bulunmuş ve in vivo çalışmaların yapılması gerektiği düşünülmüştür.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp

Methicillin-Dirençli Staphylococcus aureus Bakterilerine Karşı Verbascum thapsus L. Bitkisinin Anti-Staphylococcal Aktivitesi

Öz:
Objective: In this study, it was aimed to investigate the anti-Staphylococcalactivity of ethanol extract obtained from leaves of Verbascum thapsus L.(Scrophulariaceae) plant.Methods: The anti-Staphylococcal activity of the extract of ethanol extractedfrom the leaves of Verbascum thapsus L. (Scrophulariaceae) was investigatedagainst Methicillin-Resistant Staphylococcus aureus (MRSA) bacteria by Agarwelldiffusionmethod and microdilution method.Results: The ethanol extract showed antibacterial activity against MethicillinresistantStaphylococcus aureus (MRSA) strains (MIC <1024 µg/mL). Whencompared with Methicillin and Gentamicin, the extract was more effective againstMRSA strains.Conclusion: The use of Verbascum thapsus L. (Scrophulariaceae) as an antiStaphylococcalagent has been found to be appropriate in vitro and should beperformed invivo.
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Dülger G, TÜTENOCAKLI T, Dulger B (2017). Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. , 53 - 57.
Chicago Dülger Görkem,TÜTENOCAKLI Tülay,Dulger Basaran Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. (2017): 53 - 57.
MLA Dülger Görkem,TÜTENOCAKLI Tülay,Dulger Basaran Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. , 2017, ss.53 - 57.
AMA Dülger G,TÜTENOCAKLI T,Dulger B Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. . 2017; 53 - 57.
Vancouver Dülger G,TÜTENOCAKLI T,Dulger B Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. . 2017; 53 - 57.
IEEE Dülger G,TÜTENOCAKLI T,Dulger B "Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus." , ss.53 - 57, 2017.
ISNAD Dülger, Görkem vd. "Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus". (2017), 53-57.
APA Dülger G, TÜTENOCAKLI T, Dulger B (2017). Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. KONURALP TIP DERGİSİ, 9(1), 53 - 57.
Chicago Dülger Görkem,TÜTENOCAKLI Tülay,Dulger Basaran Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. KONURALP TIP DERGİSİ 9, no.1 (2017): 53 - 57.
MLA Dülger Görkem,TÜTENOCAKLI Tülay,Dulger Basaran Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. KONURALP TIP DERGİSİ, vol.9, no.1, 2017, ss.53 - 57.
AMA Dülger G,TÜTENOCAKLI T,Dulger B Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. KONURALP TIP DERGİSİ. 2017; 9(1): 53 - 57.
Vancouver Dülger G,TÜTENOCAKLI T,Dulger B Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus. KONURALP TIP DERGİSİ. 2017; 9(1): 53 - 57.
IEEE Dülger G,TÜTENOCAKLI T,Dulger B "Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus." KONURALP TIP DERGİSİ, 9, ss.53 - 57, 2017.
ISNAD Dülger, Görkem vd. "Anti-Staphylococcal Activity of Verbascum thapsus L. Against Methicillin-Resistant Staphylococcus aureus". KONURALP TIP DERGİSİ 9/1 (2017), 53-57.