Yıl: 2017 Cilt: 28 Sayı: 1 Sayfa Aralığı: 22 - 26 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes

Öz:
Objective: To evaluate the first-trimester renin and aldosterone levels in pregnancies complicated by prognosis of preeclampsia and/or related adverse pregnancy outcomes.Methods: We measured serum levels of renin and aldosterone in pregnant women for first trimester screening test. Total of 180 pregnant women were included in the study and 144 of them completed the study. All pregnant women were followed during pregnancy for preeclampsia and related complications. Renin and aldosterone levels in preeclampsia and/or poor obstetric prognosis group were compared with normal pregnancy outcome group.Results: Preeclampsia developed in 13 pregnant women and one or more poor obstetric outcome developed in 36 women. Renin and aldosterone levels were not significantly different in preeclamptic women or those with poor obstetric outcome compared with the controls.Conclusion: We think that maternal first trimester renin and aldosterone levels do not have a role in the pathogenesis and prediction of preeclampsia
Anahtar Kelime:

Konular: Genel ve Dahili Tıp
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Elsheikh A, Creatsas G, Mastorakos G, Milingos S, Loutradis D, Michalas S. The renin-aldosterone system during normal and hypertensive pregnancy. Arch Gynecol Obstet 2001;264:182–5.
  • 2. Easterling TR, Benedetti TJ, Schmucker BC, Millard SP. Maternal hemodynamics in normal and preeclamptic pregnancies: a longitudinal study. Obstet Gynecol 1990;76:1061–9.
  • 3. August P, Lenz T, Ales KL, Druzin ML, Edersheim TG, Hutson JM, et al. Longitudinal study of the renin-angiotensin-aldosterone system in hypertensive pregnant women: deviations related to the development of superimposed preeclampsia. Am J Obstet Gynecol 1990;163(5 Pt 1):1612–21.
  • 4. Brown MA, Nicholson E, Gallery ED. Sodium-renin-aldosterone relations in normal and hypertensive pregnancy. Br J Obstet Gynaecol 1988;95:1237–46.
  • 5. Tapia HR, Johnson CH, Strong CG. Renin angiotensin system in normal and hypertensive disease of pregnancy. Lancet 1972;2:847– 53.
  • 6. Brenner T, Evron S, Soffer D, Abramsky O. Treatment of experimental allergic encephalomyelitis in rabbits with alpha-fetoprotein. Isr J Med Sci 1985;21:945–9.
  • 7. Skinner SL, Lumbers ER, Symonds EM. Analysis of changes in the renin angiotensin system during pregnancy. Clin Sci 1972;42:479– 83.
  • 8. Kalenga MK, Thomas K, de Gasparo M, De Hertogh R. Determination of renin, angiotensin converting enzyme and angiotensin II levels in human placenta, chorion and amnion from women with pregnancy induced hypertension. Clin Endocrinol (Oxf ) 1996;44:429–33.
  • 9. Ferraris P, Quorso P, Gazzano G, Cianci M, Sala C, Turolo L, et al. Plasma active and inactive renin and fetal complications in women with high risk pregnancies. Can J Physiol Pharmacol 1991;69:1321– 6.
  • 10. Kingdom JC, McQueen J, Connell JM, Whittle MJ. Fetal angiotensin II levels and vascular (type I) angiotensin receptors in pregnancies complicated by intrauterine growth retardation. Br J Obstet Gynaecol 1993;100:476–82.
  • 11. Gökcan B, Laçin S, Atmaca F, Gürbüz A, Cantekin D. Renin and proren in levels in sera of pregnancies complicated with severe preeclampsia and lugr. Perinatoloji Dergisi 1999;7:36–9.
  • 12. Wilson M, Morganti AA, Zervoudakis I, Letcher RI, Romns BM, Von Oeyon P, et al. Blood pressure, the renin-aldosterone system and sex steroids throughout normal pregnancy. Am J Med 1980;68:97– 104.
  • 13. Lewis PJ, Boylan P, Friedman LA, Hensby CN, Downing I. Prostacyclin in pregnancy. Br Med J 1980;280:1581–2.
  • 14. Langer B, Grima M, Coquard C, Bader AM, Schlaeder G, Imbs JL. Plasma active renin, angiotensin I, and angiotensin II during pregnancy and in preeclampsia. Obstet Gynecol 1998;91:196–202.
  • 15. Ferraris P, Quorso P, Gazzano G, Cianci M, Sala C, Turolo L, et al. Plasma active and inactive renin and fetal complications in women with high risk pregnancies. Can J Physiol Pharmacol 1991;69:1321–6. 16. Lenz T. Prorenin and active renin in hum
APA Purut Y, ESİM BÜYÜKBAYRAK E, ORÇUN A, MENKE M, KARAGEYİM KARŞIDAĞ A (2017). First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. , 22 - 26.
Chicago Purut Yunus emre,ESİM BÜYÜKBAYRAK ESRA,ORÇUN Asuman,MENKE Mehmet,KARAGEYİM KARŞIDAĞ AYŞE YASEMİN First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. (2017): 22 - 26.
MLA Purut Yunus emre,ESİM BÜYÜKBAYRAK ESRA,ORÇUN Asuman,MENKE Mehmet,KARAGEYİM KARŞIDAĞ AYŞE YASEMİN First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. , 2017, ss.22 - 26.
AMA Purut Y,ESİM BÜYÜKBAYRAK E,ORÇUN A,MENKE M,KARAGEYİM KARŞIDAĞ A First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. . 2017; 22 - 26.
Vancouver Purut Y,ESİM BÜYÜKBAYRAK E,ORÇUN A,MENKE M,KARAGEYİM KARŞIDAĞ A First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. . 2017; 22 - 26.
IEEE Purut Y,ESİM BÜYÜKBAYRAK E,ORÇUN A,MENKE M,KARAGEYİM KARŞIDAĞ A "First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes." , ss.22 - 26, 2017.
ISNAD Purut, Yunus emre vd. "First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes". (2017), 22-26.
APA Purut Y, ESİM BÜYÜKBAYRAK E, ORÇUN A, MENKE M, KARAGEYİM KARŞIDAĞ A (2017). First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. Southern Clinics of Istanbul Eurasia, 28(1), 22 - 26.
Chicago Purut Yunus emre,ESİM BÜYÜKBAYRAK ESRA,ORÇUN Asuman,MENKE Mehmet,KARAGEYİM KARŞIDAĞ AYŞE YASEMİN First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. Southern Clinics of Istanbul Eurasia 28, no.1 (2017): 22 - 26.
MLA Purut Yunus emre,ESİM BÜYÜKBAYRAK ESRA,ORÇUN Asuman,MENKE Mehmet,KARAGEYİM KARŞIDAĞ AYŞE YASEMİN First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. Southern Clinics of Istanbul Eurasia, vol.28, no.1, 2017, ss.22 - 26.
AMA Purut Y,ESİM BÜYÜKBAYRAK E,ORÇUN A,MENKE M,KARAGEYİM KARŞIDAĞ A First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. Southern Clinics of Istanbul Eurasia. 2017; 28(1): 22 - 26.
Vancouver Purut Y,ESİM BÜYÜKBAYRAK E,ORÇUN A,MENKE M,KARAGEYİM KARŞIDAĞ A First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes. Southern Clinics of Istanbul Eurasia. 2017; 28(1): 22 - 26.
IEEE Purut Y,ESİM BÜYÜKBAYRAK E,ORÇUN A,MENKE M,KARAGEYİM KARŞIDAĞ A "First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes." Southern Clinics of Istanbul Eurasia, 28, ss.22 - 26, 2017.
ISNAD Purut, Yunus emre vd. "First Trimester Renin and Aldosterone Levels of Pregnant Women With Prognosis of Preeclampsia and/or Related Adverse Pregnancy Outcomes". Southern Clinics of Istanbul Eurasia 28/1 (2017), 22-26.