Yıl: 2017 Cilt: 27 Sayı: 3 Sayfa Aralığı: 115 - 121 Metin Dili: Türkçe İndeks Tarihi: 29-07-2022

Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi

Öz:
Amaç: Bu çalışmada ekstra tiroidal uzantılı ileri tiroid karsinomunun tedavisi değerlendirildi.Hastalar ve Yöntemler: Çalışmaya genel cerrahi veya diğer kulak-burun-boğaz bölümlerinden sevk edilen ve Ocak 2007 - Ocak 2011 tarihleri arasında T4a iyi diferansiye tiroid karsinomu veya T4b anaplastik karsinomu nedeniyle cerrahi geçiren, en az beş yıl takip edilen 58 hasta (26 erkek, 32 kadın; ort. yaş 45.1±8.3 yıl; dağılım 24-72 yıl) dahil edildi. Larengotrakeal invazyonu olan hastalar cerrahi türüne göre iki gruba ayrıldı. İnvazyon paternleri ve cerrahi rezeksiyon teknikleri değerlendirildi.Bulgular: Grup 1'deki hastaların (n=24) tamamına (%100) total tiroidektomi, altısına (%10.4) parsiyel larenjektomi, sekizine (%13) trakeal rezeksiyon ve 16'sına (%27) trakeal pencere rezeksiyonu uygulandı; serbest marjinler dondurulmuş kesit ile doğrulandı. Grup 2'deki hastalara (n=34) tümörü alttaki kıkırdaktan kazıyarak veya larengotrakeal segmentleri iskeletleştirerek total tiroidektomi (%100) uygulandı. Takip dönemi sırasında, bir hasta karotis tutulumu ve dört hasta lokal rekürens nedeniyle kaybedildi.Sonuç: Bu çalışmanın bulguları ekstra tiroidal uzantılı ileri tiroid karsinomlu hastalar için cerrahi bir yaklaşım seçilirken invazyon derinliğinin ve ameliyat sonrası morbiditenin dikkate alınması gerektiğini ortaya koymaktadır. Ayrıca, tümör kazıması geçiren hastalar yakından takip edilmelidir
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel Anestezi Üroloji ve Nefroloji Tıbbi Laboratuar Teknolojisi Cerrahi Ortopedi

Management of advanced thyroid carcinoma with laryngotracheal invasion

Öz:
Objectives: This study aims to evaluate the management of advanced thyroid carcinoma with extra-thyroidal extension.Patients and Methods: The study included 58 patients (26 males, 32 females; mean age 45.1±8.3 years; range 24 to 72 years) who were referred from general surgery or other otolaryngology departments and had undergone surgery for T4a well-differentiated thyroid carcinoma or T4b anaplastic carcinoma between January 2007 and January 2011 with a minimum of five years of follow-up. The patients with laryngotracheal invasion were divided into two groups according to type of surgery. Patterns of invasion and techniques of surgical resection were evaluated.Results: Of the patients in group 1 (n=24), total thyroidectomy was performed in all (100%), partial laryngectomy in six (10.4%), tracheal resection in eight (13%), and tracheal window resection in 16 (27%), and the free margins were verified by frozen section. Patients in group 2 (n=34) were performed total thyroidectomy (100%) by shaving the tumor off the underlying cartilage or skeletonizing laryngotracheal segments. During the follow-up period, one patient died because of carotid involvement and four patients died because of local recurrence.Conclusion: The results of this study suggest that the depth of the invasion and postoperative morbidity should be considered when choosing a surgical approach for patients with advanced thyroid carcinoma with extra-thyroidal extension. Also, patients who undergo tumor shaving should be followed-up closely
Anahtar Kelime:

Konular: Tıbbi Araştırmalar Deneysel Anestezi Üroloji ve Nefroloji Tıbbi Laboratuar Teknolojisi Cerrahi Ortopedi
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Batioglu-Karaaltin A, YENER M, YILMAZ M, TURGUT N, PAMUKÇU M, CANSIZ H (2017). Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. , 115 - 121.
Chicago Batioglu-Karaaltin Aysegul,YENER Murat Haydar,YILMAZ MEHMET,TURGUT NESRETTIN FATIH,PAMUKÇU Muhammed,CANSIZ Harun Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. (2017): 115 - 121.
MLA Batioglu-Karaaltin Aysegul,YENER Murat Haydar,YILMAZ MEHMET,TURGUT NESRETTIN FATIH,PAMUKÇU Muhammed,CANSIZ Harun Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. , 2017, ss.115 - 121.
AMA Batioglu-Karaaltin A,YENER M,YILMAZ M,TURGUT N,PAMUKÇU M,CANSIZ H Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. . 2017; 115 - 121.
Vancouver Batioglu-Karaaltin A,YENER M,YILMAZ M,TURGUT N,PAMUKÇU M,CANSIZ H Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. . 2017; 115 - 121.
IEEE Batioglu-Karaaltin A,YENER M,YILMAZ M,TURGUT N,PAMUKÇU M,CANSIZ H "Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi." , ss.115 - 121, 2017.
ISNAD Batioglu-Karaaltin, Aysegul vd. "Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi". (2017), 115-121.
APA Batioglu-Karaaltin A, YENER M, YILMAZ M, TURGUT N, PAMUKÇU M, CANSIZ H (2017). Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. Kulak Burun Boğaz İhtisas Dergisi, 27(3), 115 - 121.
Chicago Batioglu-Karaaltin Aysegul,YENER Murat Haydar,YILMAZ MEHMET,TURGUT NESRETTIN FATIH,PAMUKÇU Muhammed,CANSIZ Harun Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. Kulak Burun Boğaz İhtisas Dergisi 27, no.3 (2017): 115 - 121.
MLA Batioglu-Karaaltin Aysegul,YENER Murat Haydar,YILMAZ MEHMET,TURGUT NESRETTIN FATIH,PAMUKÇU Muhammed,CANSIZ Harun Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. Kulak Burun Boğaz İhtisas Dergisi, vol.27, no.3, 2017, ss.115 - 121.
AMA Batioglu-Karaaltin A,YENER M,YILMAZ M,TURGUT N,PAMUKÇU M,CANSIZ H Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. Kulak Burun Boğaz İhtisas Dergisi. 2017; 27(3): 115 - 121.
Vancouver Batioglu-Karaaltin A,YENER M,YILMAZ M,TURGUT N,PAMUKÇU M,CANSIZ H Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi. Kulak Burun Boğaz İhtisas Dergisi. 2017; 27(3): 115 - 121.
IEEE Batioglu-Karaaltin A,YENER M,YILMAZ M,TURGUT N,PAMUKÇU M,CANSIZ H "Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi." Kulak Burun Boğaz İhtisas Dergisi, 27, ss.115 - 121, 2017.
ISNAD Batioglu-Karaaltin, Aysegul vd. "Larengotrakeal invazyonlu ileri tiroid karsinomunun tedavisi". Kulak Burun Boğaz İhtisas Dergisi 27/3 (2017), 115-121.