Human being as an ill-pleased with the condition, the space and the mental process has always found itself in a quest and adventure since his beginning or creation. As a matter of fact, we track human’s quest and adventure in the story beginning with Adam, in the mythology he has built, in the philosophy-science he has developed, within its approach in Renaissance and Enlightenment periods, on commercial capitalism, at industrialization and finally in the time of technology. Human has dared to alter the conditions with a fruit consumed, with a fire lightened and the repositioning of God in his mind, that is to say, with mythological imagination and theological approaches, with the imagination of mind and philosophy (philosophy-science) on the thought and the phenomenon and with the use of tools and machines (technical-industry). The human-god unity in medieval Christianity, the secular-materialistic approach during the Renaissance and the Enlightenment, the courses of industrialization and capitalism triggered by positivism, gave birth to a materialized person who is deprived of metaphysics. The humanism process –an attempt displacing god with the human- has not relieved the human being. The high tech process in 1970s created transhumanism that transcended humanism. Not to be satisfied enough by replacing himself with the god, human has started a struggle to overcome aging, disease, biological defects, pain or ache, foolishness, even death. Now, in a cause of constructing the trans-human, the human being seeks welfare for his own generation, to make them live in a world that is painless and discrete. By trying to transcend biological and physical boundaries of himself, the human being has put himself into both cyborg and deification processes. He has not contended with humanism but rushed to enter in the course of transhumanism