Two siblings with familial subclinical hyperthyroidism with unknown etiology
Yıl: 2017 Cilt: 6 Sayı: 1 Sayfa Aralığı: 154 - 156 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022
Two siblings with familial subclinical hyperthyroidism with unknown etiology
Öz: Subclinical hyperthyroidism is defined as low or undetectable concentration of serum thyrotrophin (TSH) with normal free triiodothyronine (FT3) and free thyroxine (FT4) levels. 1). Familial subclinical hyperthyroidism is a rare entity. Activating mutations of the TSH receptor (TSH-R) gene cause genetic hyperthyroidism. Here we present a family with more than one affected individual. All family members were investigated for TSH-R mutation. No mutation was detected, while a A459 polymorphism was found in one of the cases and three other siblings. Despite the clinical and biochemical findings suggesting a TSH-R mutation, a reasonable cause could not be detected. Epigenetic and environmental modifiers, including iodine intake, should be considered in families with mutation negative, familial non auto-immune hyperthyroidism (FNAH)
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ÖZSU E, MUTLU G, ÇİZMECİOĞLU F, BİRCAN R, HATUN Ş (2017). Two siblings with familial subclinical hyperthyroidism with unknown etiology. , 154 - 156. |
| Chicago | ÖZSU Elif,MUTLU Gul Yesiltepe,ÇİZMECİOĞLU Filiz Mine,BİRCAN Rifat,HATUN Şükrü Two siblings with familial subclinical hyperthyroidism with unknown etiology. (2017): 154 - 156. |
| MLA | ÖZSU Elif,MUTLU Gul Yesiltepe,ÇİZMECİOĞLU Filiz Mine,BİRCAN Rifat,HATUN Şükrü Two siblings with familial subclinical hyperthyroidism with unknown etiology. , 2017, ss.154 - 156. |
| AMA | ÖZSU E,MUTLU G,ÇİZMECİOĞLU F,BİRCAN R,HATUN Ş Two siblings with familial subclinical hyperthyroidism with unknown etiology. . 2017; 154 - 156. |
| Vancouver | ÖZSU E,MUTLU G,ÇİZMECİOĞLU F,BİRCAN R,HATUN Ş Two siblings with familial subclinical hyperthyroidism with unknown etiology. . 2017; 154 - 156. |
| IEEE | ÖZSU E,MUTLU G,ÇİZMECİOĞLU F,BİRCAN R,HATUN Ş "Two siblings with familial subclinical hyperthyroidism with unknown etiology." , ss.154 - 156, 2017. |
| ISNAD | ÖZSU, Elif vd. "Two siblings with familial subclinical hyperthyroidism with unknown etiology". (2017), 154-156. |
| APA | ÖZSU E, MUTLU G, ÇİZMECİOĞLU F, BİRCAN R, HATUN Ş (2017). Two siblings with familial subclinical hyperthyroidism with unknown etiology. Medicine Science, 6(1), 154 - 156. |
| Chicago | ÖZSU Elif,MUTLU Gul Yesiltepe,ÇİZMECİOĞLU Filiz Mine,BİRCAN Rifat,HATUN Şükrü Two siblings with familial subclinical hyperthyroidism with unknown etiology. Medicine Science 6, no.1 (2017): 154 - 156. |
| MLA | ÖZSU Elif,MUTLU Gul Yesiltepe,ÇİZMECİOĞLU Filiz Mine,BİRCAN Rifat,HATUN Şükrü Two siblings with familial subclinical hyperthyroidism with unknown etiology. Medicine Science, vol.6, no.1, 2017, ss.154 - 156. |
| AMA | ÖZSU E,MUTLU G,ÇİZMECİOĞLU F,BİRCAN R,HATUN Ş Two siblings with familial subclinical hyperthyroidism with unknown etiology. Medicine Science. 2017; 6(1): 154 - 156. |
| Vancouver | ÖZSU E,MUTLU G,ÇİZMECİOĞLU F,BİRCAN R,HATUN Ş Two siblings with familial subclinical hyperthyroidism with unknown etiology. Medicine Science. 2017; 6(1): 154 - 156. |
| IEEE | ÖZSU E,MUTLU G,ÇİZMECİOĞLU F,BİRCAN R,HATUN Ş "Two siblings with familial subclinical hyperthyroidism with unknown etiology." Medicine Science, 6, ss.154 - 156, 2017. |
| ISNAD | ÖZSU, Elif vd. "Two siblings with familial subclinical hyperthyroidism with unknown etiology". Medicine Science 6/1 (2017), 154-156. |
