Yıl: 2018 Cilt: 11 Sayı: 1 Sayfa Aralığı: 19 - 24 Metin Dili: İngilizce DOI: 10.5505/ptd.2017.60437 İndeks Tarihi: 04-01-2019

The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis

Öz:
Purpose: Rheumatoid arthritis (RA) is a disease that characterized by joint damage including periarticularosteoporosis and focal bone erosion. Despite the fact that periarticular osteoporosis and erosions are knownas radiographic hallmarks of RA, there is a lack of data on the relationship between forearm bone loss andradiographic damage. For this reason, we aimed in this study to determine whether there is a relationshipbetween focal erosions and OP in RA patients.Materials and methods: We evaluated 49 female patients with RA. Anteroposterior hand and foot radiographsand bone mineral density measurement of forearm, hip and lumbar spine with dual x-ray absorptiometry of allpatients were taken at simultaneously. Radiographs were analyzed using the Larsen method. Disease activitywas evaluated by DAS-28 and functional ability was measured with Health Assessment Questionnaire andDuruöz Hand Index.Results:Patients had the mean age 53.9±11.8 and an average disease duration of 7.9±5.9 years. The erosionscore was correlated with bone mineral density of forearm, but not with lumbar spine and hip. The diseaseactivity and functional ability were not correlated with Larsen score. Both osteoporosis in all evaluated area andcorrelations were not affected by the menopause status and disease duration.Conclusion: Our results demonstrated that bone mineral density of forearm indicate the erosion severity infemale patients with RA.
Anahtar Kelime:

Romatoid Artritli bayan hastalarda eklem erozyonları ile ön kol kemik mineral yoğunluğu arasındaki ilişki

Öz:
Amaç: Romatoid artrit (RA) periartiküler osteoporoz ve erozyonların dahil olduğu eklem hasarı ile karakterize bir hastalıktır. Periartiküler osteoporoz ve erozyonlar RA’da iyi bilinen radyolojik bulgular olmasına rağmen, ön kol kemik mineral yoğunluğu ile radyografik hasar arasındaki ilişkiye dair çok az veri mevcuttur. Bu nedenle çalışmamızda RA’da fokal erozyonlar ile osteoporoz arasında ilişki olup olmadığını belirlemeyi amaçladık. Gereç ve yöntem: Romatoid artritli 49 bayan hasta değerlendirildi. Hastaların tümünün el ve ayak grafileri ile ön kol, lomber ve kalça dual-x ray absorbsiyometri ölçümleri yapıldı. Radyografiler Larsen yöntemi ile değerlendirildi. Hastalık aktivitesi DAS-28 ile ve fonksiyonel durum Genel Sağlık anketi ve Duruöz El İndeksi ile değerlendirildi. Bulgular: Hastaların yaş ortalaması 53.9±11.8 ve ortalama hastalık süresi 7.9±5.9 yıldı. Erozyon skoru, ön kol kemik mineral dansitesi ile korele iken lomber vertebra ve kalça ile korele değildi. Hastalık aktivitesi ve fonksiyonel durum Larsen skoru ile korele değildi. Gerek değerlendirilen bölgelerdeki osteoporoz, gerekse korelasyonlar menopoz durumu ve hastalık süresinden etkilenmedi. Sonuç: Sonuçlarımız RA’lı bayan hastalarda ön kol kemik mineral dansitesinin erozyon şiddetini gösterdiğini belirtmektedir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA TAŞÇI BOZBAŞ G, gurer g, ŞENDUR Ö (2018). The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. , 19 - 24. 10.5505/ptd.2017.60437
Chicago TAŞÇI BOZBAŞ GÜLNUR,gurer gülcan,ŞENDUR Ömer Faruk The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. (2018): 19 - 24. 10.5505/ptd.2017.60437
MLA TAŞÇI BOZBAŞ GÜLNUR,gurer gülcan,ŞENDUR Ömer Faruk The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. , 2018, ss.19 - 24. 10.5505/ptd.2017.60437
AMA TAŞÇI BOZBAŞ G,gurer g,ŞENDUR Ö The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. . 2018; 19 - 24. 10.5505/ptd.2017.60437
Vancouver TAŞÇI BOZBAŞ G,gurer g,ŞENDUR Ö The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. . 2018; 19 - 24. 10.5505/ptd.2017.60437
IEEE TAŞÇI BOZBAŞ G,gurer g,ŞENDUR Ö "The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis." , ss.19 - 24, 2018. 10.5505/ptd.2017.60437
ISNAD TAŞÇI BOZBAŞ, GÜLNUR vd. "The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis". (2018), 19-24. https://doi.org/10.5505/ptd.2017.60437
APA TAŞÇI BOZBAŞ G, gurer g, ŞENDUR Ö (2018). The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. Pamukkale Tıp Dergisi, 11(1), 19 - 24. 10.5505/ptd.2017.60437
Chicago TAŞÇI BOZBAŞ GÜLNUR,gurer gülcan,ŞENDUR Ömer Faruk The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. Pamukkale Tıp Dergisi 11, no.1 (2018): 19 - 24. 10.5505/ptd.2017.60437
MLA TAŞÇI BOZBAŞ GÜLNUR,gurer gülcan,ŞENDUR Ömer Faruk The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. Pamukkale Tıp Dergisi, vol.11, no.1, 2018, ss.19 - 24. 10.5505/ptd.2017.60437
AMA TAŞÇI BOZBAŞ G,gurer g,ŞENDUR Ö The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. Pamukkale Tıp Dergisi. 2018; 11(1): 19 - 24. 10.5505/ptd.2017.60437
Vancouver TAŞÇI BOZBAŞ G,gurer g,ŞENDUR Ö The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis. Pamukkale Tıp Dergisi. 2018; 11(1): 19 - 24. 10.5505/ptd.2017.60437
IEEE TAŞÇI BOZBAŞ G,gurer g,ŞENDUR Ö "The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis." Pamukkale Tıp Dergisi, 11, ss.19 - 24, 2018. 10.5505/ptd.2017.60437
ISNAD TAŞÇI BOZBAŞ, GÜLNUR vd. "The relation between joint erosion and forearm bone mineral density in female patient with rheumatoid arthritis". Pamukkale Tıp Dergisi 11/1 (2018), 19-24. https://doi.org/10.5505/ptd.2017.60437