The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible

Mehmet Erman ERDEMLİ, (Omer Halisdemir University, Faculty of Medicine, Department of Medical Biochemistry, Nigde, Turkey)
Hasan AKGÜL, (Akdeniz University, Faculty of Arts and Science, Department of Biology, Antalya, Turkey)
Bilal EGE, (Adiyaman University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Adiyaman, Turkey)
Zeynep AKSUNGUR, (Inonu University, Faculty of Medicine, Department of Medical Biochemistry, Malatya, Turkey)
Harika Gözde GÖZÜKARA BAĞ, (Inonu University, Faculty of Medicine, Departmant of Bioistatistic, Malatya, Turkey)
ZELİHA SELAMOĞLU (Omer Halisdemir University, Faculty of Arts and Science, Department of Biotechnology, Nigde, Turkey)
İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi
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Yıl: 2017 Cilt: 24 Sayı: 2 Sayfa Aralığı: 127 - 133 Metin Dili: İngilizce DOI: 10.5455/jtomc.2016.12.131 İndeks Tarihi: 17-09-2018

The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible

Öz:
Aim: The present study investigated the changes in the liver tissues of rats with experimentally fractured mandible following the use of Grape Extract (GSE) and Low Level Laser Therapy (LLLT) in healing the fracture in dentistry.Materials and Methods: 60 adult male Wistar Albino rats were randomly assigned to 5 main groups (Control, Fractured Mandible (FM), FM + GSE, FM + LLLT, FM + LLLT + GSE), and then these groups were divided into two groups of 7 and 21 days (n = 6). A vertical fracture line passing through the molar teeth was formed in the right mandibles of all subjects except for these in the control group, and the fracture was internally fixed with a four-hole microplate and four micro-screws. Malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT) activities were analyzed to determine the changes caused by GSE and LLLT administration in rat liver tissues in fractured mandibles.Results: It was determined that MDA and SOD levels in FM group and GSH and CAT activity levels in FM + GSE group and MDA levels in FM + LLLT group and GSH and CAT levels in FM + GSE + LLLT group increased statistically significantly to the control group on days 7 and21.Conclusion: Biochemical parameters were investigated on the 7th and the 21st days, and it was determined that the oxidative damagecaused by mandibular defects could be eliminated substantially in the rat liver especially with the administration of grapeseed that has antioxidant capacity.
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APA erdemli m, AKGÜL H, Ege B, AKSUNGUR Z, GÖZÜKARA BAĞ H, SELAMOĞLU Z (2017). The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. , 127 - 133. 10.5455/jtomc.2016.12.131
Chicago erdemli mehmet erman,AKGÜL Hasan,Ege Bilal,AKSUNGUR Zeynep,GÖZÜKARA BAĞ Harika Gözde,SELAMOĞLU Zeliha The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. (2017): 127 - 133. 10.5455/jtomc.2016.12.131
MLA erdemli mehmet erman,AKGÜL Hasan,Ege Bilal,AKSUNGUR Zeynep,GÖZÜKARA BAĞ Harika Gözde,SELAMOĞLU Zeliha The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. , 2017, ss.127 - 133. 10.5455/jtomc.2016.12.131
AMA erdemli m,AKGÜL H,Ege B,AKSUNGUR Z,GÖZÜKARA BAĞ H,SELAMOĞLU Z The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. . 2017; 127 - 133. 10.5455/jtomc.2016.12.131
Vancouver erdemli m,AKGÜL H,Ege B,AKSUNGUR Z,GÖZÜKARA BAĞ H,SELAMOĞLU Z The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. . 2017; 127 - 133. 10.5455/jtomc.2016.12.131
IEEE erdemli m,AKGÜL H,Ege B,AKSUNGUR Z,GÖZÜKARA BAĞ H,SELAMOĞLU Z "The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible." , ss.127 - 133, 2017. 10.5455/jtomc.2016.12.131
ISNAD erdemli, mehmet erman vd. "The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible". (2017), 127-133. https://doi.org/10.5455/jtomc.2016.12.131
APA erdemli m, AKGÜL H, Ege B, AKSUNGUR Z, GÖZÜKARA BAĞ H, SELAMOĞLU Z (2017). The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 24(2), 127 - 133. 10.5455/jtomc.2016.12.131
Chicago erdemli mehmet erman,AKGÜL Hasan,Ege Bilal,AKSUNGUR Zeynep,GÖZÜKARA BAĞ Harika Gözde,SELAMOĞLU Zeliha The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 24, no.2 (2017): 127 - 133. 10.5455/jtomc.2016.12.131
MLA erdemli mehmet erman,AKGÜL Hasan,Ege Bilal,AKSUNGUR Zeynep,GÖZÜKARA BAĞ Harika Gözde,SELAMOĞLU Zeliha The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, vol.24, no.2, 2017, ss.127 - 133. 10.5455/jtomc.2016.12.131
AMA erdemli m,AKGÜL H,Ege B,AKSUNGUR Z,GÖZÜKARA BAĞ H,SELAMOĞLU Z The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2017; 24(2): 127 - 133. 10.5455/jtomc.2016.12.131
Vancouver erdemli m,AKGÜL H,Ege B,AKSUNGUR Z,GÖZÜKARA BAĞ H,SELAMOĞLU Z The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi. 2017; 24(2): 127 - 133. 10.5455/jtomc.2016.12.131
IEEE erdemli m,AKGÜL H,Ege B,AKSUNGUR Z,GÖZÜKARA BAĞ H,SELAMOĞLU Z "The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible." İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 24, ss.127 - 133, 2017. 10.5455/jtomc.2016.12.131
ISNAD erdemli, mehmet erman vd. "The effects of grapeseed extract and low level laser therapy administration on the liver in experimentally fractured mandible". İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi 24/2 (2017), 127-133. https://doi.org/10.5455/jtomc.2016.12.131
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17-04-2024 10:29

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