Dynamic thiol/disulphide homeostasis in acute pancreatitis
Yıl: 2018 Cilt: 29 Sayı: 3 Sayfa Aralığı: 348 - 353 Metin Dili: İngilizce İndeks Tarihi: 21-12-2018
Dynamic thiol/disulphide homeostasis in acute pancreatitis
Öz: Background/Aims: The dynamic thiol/disulfide homeostasis plays pivotal roles in many physiological mechanisms in an organism. We aimed to investigate whether dynamic thiol/disulfide homeostasis changes among patients with acute pancreatitis.Materials and Methods: This prospective trial contained 45 patients with acute pancreatitis and 45 sex-and age-matched healthy vol-unteers as control group. Thiol/disulfide homeostasis parameters were measured by a novel and automated assay, and detected results were compared between the two groups.Results: Disulfide/total thiol percent ratio and disulfide/native thiol percent ratios were significantly higher in acute pancreatitis group;besides the native thiol, total thiol levels and native thiol/total thiol percent ratios were significantly lower (for all p<0.001). Conclusion: The thiol/disulfide homeostasis is impaired in acute pancreatitis with a shift toward the oxidative status, and this deficiency might be a pathogenic factor in acute pancreatitis. The correction of this thiol/disulfide imbalance may be a new target in the manage-ment of acute pancreatitis.
Anahtar Kelime: Konular:
Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Köseoğlu H, Alisik M, Başaran M, TAYFUR YÜREKLİ Ö, Solakoglu T, TAHTACI M, ERSOY O, EREL O (2018). Dynamic thiol/disulphide homeostasis in acute pancreatitis. , 348 - 353. |
| Chicago | Köseoğlu Hüseyin,Alisik Murat,Başaran Murat,TAYFUR YÜREKLİ ÖYKÜ,Solakoglu Tevfik,TAHTACI Mustafa,ERSOY Osman,EREL Ozcan Dynamic thiol/disulphide homeostasis in acute pancreatitis. (2018): 348 - 353. |
| MLA | Köseoğlu Hüseyin,Alisik Murat,Başaran Murat,TAYFUR YÜREKLİ ÖYKÜ,Solakoglu Tevfik,TAHTACI Mustafa,ERSOY Osman,EREL Ozcan Dynamic thiol/disulphide homeostasis in acute pancreatitis. , 2018, ss.348 - 353. |
| AMA | Köseoğlu H,Alisik M,Başaran M,TAYFUR YÜREKLİ Ö,Solakoglu T,TAHTACI M,ERSOY O,EREL O Dynamic thiol/disulphide homeostasis in acute pancreatitis. . 2018; 348 - 353. |
| Vancouver | Köseoğlu H,Alisik M,Başaran M,TAYFUR YÜREKLİ Ö,Solakoglu T,TAHTACI M,ERSOY O,EREL O Dynamic thiol/disulphide homeostasis in acute pancreatitis. . 2018; 348 - 353. |
| IEEE | Köseoğlu H,Alisik M,Başaran M,TAYFUR YÜREKLİ Ö,Solakoglu T,TAHTACI M,ERSOY O,EREL O "Dynamic thiol/disulphide homeostasis in acute pancreatitis." , ss.348 - 353, 2018. |
| ISNAD | Köseoğlu, Hüseyin vd. "Dynamic thiol/disulphide homeostasis in acute pancreatitis". (2018), 348-353. |
| APA | Köseoğlu H, Alisik M, Başaran M, TAYFUR YÜREKLİ Ö, Solakoglu T, TAHTACI M, ERSOY O, EREL O (2018). Dynamic thiol/disulphide homeostasis in acute pancreatitis. Turkish Journal of Gastroenterology, 29(3), 348 - 353. |
| Chicago | Köseoğlu Hüseyin,Alisik Murat,Başaran Murat,TAYFUR YÜREKLİ ÖYKÜ,Solakoglu Tevfik,TAHTACI Mustafa,ERSOY Osman,EREL Ozcan Dynamic thiol/disulphide homeostasis in acute pancreatitis. Turkish Journal of Gastroenterology 29, no.3 (2018): 348 - 353. |
| MLA | Köseoğlu Hüseyin,Alisik Murat,Başaran Murat,TAYFUR YÜREKLİ ÖYKÜ,Solakoglu Tevfik,TAHTACI Mustafa,ERSOY Osman,EREL Ozcan Dynamic thiol/disulphide homeostasis in acute pancreatitis. Turkish Journal of Gastroenterology, vol.29, no.3, 2018, ss.348 - 353. |
| AMA | Köseoğlu H,Alisik M,Başaran M,TAYFUR YÜREKLİ Ö,Solakoglu T,TAHTACI M,ERSOY O,EREL O Dynamic thiol/disulphide homeostasis in acute pancreatitis. Turkish Journal of Gastroenterology. 2018; 29(3): 348 - 353. |
| Vancouver | Köseoğlu H,Alisik M,Başaran M,TAYFUR YÜREKLİ Ö,Solakoglu T,TAHTACI M,ERSOY O,EREL O Dynamic thiol/disulphide homeostasis in acute pancreatitis. Turkish Journal of Gastroenterology. 2018; 29(3): 348 - 353. |
| IEEE | Köseoğlu H,Alisik M,Başaran M,TAYFUR YÜREKLİ Ö,Solakoglu T,TAHTACI M,ERSOY O,EREL O "Dynamic thiol/disulphide homeostasis in acute pancreatitis." Turkish Journal of Gastroenterology, 29, ss.348 - 353, 2018. |
| ISNAD | Köseoğlu, Hüseyin vd. "Dynamic thiol/disulphide homeostasis in acute pancreatitis". Turkish Journal of Gastroenterology 29/3 (2018), 348-353. |
