Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy

ÇETİN, Mustafa; KARAYAKALI, Muammer; ÖZBAY ÖZYILMAZ, SİNEM; BAKIR, İhsan; PÜŞÜROĞLU, Hamdi; GÜL, MEHMET; UYAREL, Hüseyin; Akgul, Ozgur; YILDIRIM, Aydin; SATILMIŞOĞLU, Hulusi

Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy

SİNEM ÖZBAY ÖZYILMAZ, (Department of Cardiology, Faculty of Medicine, Biruni University; İstanbul-Turkey)

Özgür AKGÜL, (Cardiology)

Hüseyin UYAREL, (Cardiology, Faculty of Medicine, Bezmialem Vakıf University; İstanbul-Turkey)

Hamdi PÜŞÜROĞLU, (Cardiology)

Muammer KARAYAKALI, (Cardiology)

Mehmet GÜL, (Cardiology)

Mustafa ÇETİN, (Cardiology, Faculty of Medicine, Recep Tayyip Erdoğan University; Rize-Turkey)

Hulusi SATILMIŞOĞLU, (Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center)

Aydın YILDIRIM, (Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center)

İhsan BAKIR (Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center)

The Anatolian Journal of Cardiology

1 1

Yıl: 2017 Cilt: 18 Sayı: 1 Sayfa Aralığı: 54 - 61 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy

Öz:

Objective: It has been shown that the presence of fragmented QRS (fQRS) is associated with poor prognosis in many cardiovascular diseases and in patients with hypertrophic cardiomyopathy (HCM). However, no study has shown an association with the absolute risk score of sudden cardiac death. The aim of this study was to determine the relationship between QRS and the predicted risk score of sudden cardiac death at 5 years (HCM Risk-SCD) in HCM patients.Methods: In total, 115 consecutive HCM patients were included in this prospective observational study. The patients were divided into two groups according to the presence [fQRS(+) group (n=65)] or absence [fQRS(–) group (n=50)] of fQRS on a 12-lead electrocardiogram (ECG).Results: The HCM Risk-SCD (%) HCM Risk-SCD (>6%) values and some echocardiographic parameters, including ventricular extrasystole, ventricular tachycardia, cardiopulmonary resuscitation, implantable cardioverter defibrillator implantation, appropriate shock, and heart failure at the time of admission, were significantly higher in the fQRS(+) group than in the fQRS(–) group (all p<0.05). Both univariate and multivariate analyses revealed fQRS and New York Heart Association (NYHA) class as independent predictors of HCM Risk-SCD. In a receiver operating characteristic (ROC) curve analysis, an HCM Risk-SCD value of >4 was identified as an effective cut-off point in fQRS for HCM. An HCM Risk-SCD value of >4 yielded a sensitivity of 77% and a specificity of 76%.Conclusion: fQRS is determined to be an independent high-risk indicator of HCM Risk-SCD. It seems to be associated with increased ventricular arrhythmias and some echocardiographic parameters

Anahtar Kelime:

Konular: Kalp ve Kalp Damar Sistemi

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ÖZBAY ÖZYILMAZ S, Akgul O, UYAREL H, PÜŞÜROĞLU H, KARAYAKALI M, GÜL M, ÇETİN M, SATILMIŞOĞLU H, YILDIRIM A, BAKIR İ (2017). Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. , 54 - 61.
Chicago	ÖZBAY ÖZYILMAZ SİNEM,Akgul Ozgur,UYAREL Hüseyin,PÜŞÜROĞLU Hamdi,KARAYAKALI Muammer,GÜL MEHMET,ÇETİN Mustafa,SATILMIŞOĞLU Hulusi,YILDIRIM Aydin,BAKIR İhsan Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. (2017): 54 - 61.
MLA	ÖZBAY ÖZYILMAZ SİNEM,Akgul Ozgur,UYAREL Hüseyin,PÜŞÜROĞLU Hamdi,KARAYAKALI Muammer,GÜL MEHMET,ÇETİN Mustafa,SATILMIŞOĞLU Hulusi,YILDIRIM Aydin,BAKIR İhsan Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. , 2017, ss.54 - 61.
AMA	ÖZBAY ÖZYILMAZ S,Akgul O,UYAREL H,PÜŞÜROĞLU H,KARAYAKALI M,GÜL M,ÇETİN M,SATILMIŞOĞLU H,YILDIRIM A,BAKIR İ Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. . 2017; 54 - 61.
Vancouver	ÖZBAY ÖZYILMAZ S,Akgul O,UYAREL H,PÜŞÜROĞLU H,KARAYAKALI M,GÜL M,ÇETİN M,SATILMIŞOĞLU H,YILDIRIM A,BAKIR İ Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. . 2017; 54 - 61.
IEEE	ÖZBAY ÖZYILMAZ S,Akgul O,UYAREL H,PÜŞÜROĞLU H,KARAYAKALI M,GÜL M,ÇETİN M,SATILMIŞOĞLU H,YILDIRIM A,BAKIR İ "Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy." , ss.54 - 61, 2017.
ISNAD	ÖZBAY ÖZYILMAZ, SİNEM vd. "Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy". (2017), 54-61.

APA	ÖZBAY ÖZYILMAZ S, Akgul O, UYAREL H, PÜŞÜROĞLU H, KARAYAKALI M, GÜL M, ÇETİN M, SATILMIŞOĞLU H, YILDIRIM A, BAKIR İ (2017). Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. The Anatolian Journal of Cardiology, 18(1), 54 - 61.
Chicago	ÖZBAY ÖZYILMAZ SİNEM,Akgul Ozgur,UYAREL Hüseyin,PÜŞÜROĞLU Hamdi,KARAYAKALI Muammer,GÜL MEHMET,ÇETİN Mustafa,SATILMIŞOĞLU Hulusi,YILDIRIM Aydin,BAKIR İhsan Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. The Anatolian Journal of Cardiology 18, no.1 (2017): 54 - 61.
MLA	ÖZBAY ÖZYILMAZ SİNEM,Akgul Ozgur,UYAREL Hüseyin,PÜŞÜROĞLU Hamdi,KARAYAKALI Muammer,GÜL MEHMET,ÇETİN Mustafa,SATILMIŞOĞLU Hulusi,YILDIRIM Aydin,BAKIR İhsan Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. The Anatolian Journal of Cardiology, vol.18, no.1, 2017, ss.54 - 61.
AMA	ÖZBAY ÖZYILMAZ S,Akgul O,UYAREL H,PÜŞÜROĞLU H,KARAYAKALI M,GÜL M,ÇETİN M,SATILMIŞOĞLU H,YILDIRIM A,BAKIR İ Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. The Anatolian Journal of Cardiology. 2017; 18(1): 54 - 61.
Vancouver	ÖZBAY ÖZYILMAZ S,Akgul O,UYAREL H,PÜŞÜROĞLU H,KARAYAKALI M,GÜL M,ÇETİN M,SATILMIŞOĞLU H,YILDIRIM A,BAKIR İ Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy. The Anatolian Journal of Cardiology. 2017; 18(1): 54 - 61.
IEEE	ÖZBAY ÖZYILMAZ S,Akgul O,UYAREL H,PÜŞÜROĞLU H,KARAYAKALI M,GÜL M,ÇETİN M,SATILMIŞOĞLU H,YILDIRIM A,BAKIR İ "Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy." The Anatolian Journal of Cardiology, 18, ss.54 - 61, 2017.
ISNAD	ÖZBAY ÖZYILMAZ, SİNEM vd. "Assessment of the association between the presence of fragmented QRS and the predicted risk score of sudden cardiac death at 5 years in patients with hypertrophic cardiomyopathy". The Anatolian Journal of Cardiology 18/1 (2017), 54-61.