Evaluation of the ambulatory arterial stiffness index in lead-exposed workers

bal, ceylan; Yılmaz, Ömer Hinç; KARAKULAK, Uğur Nadir; ateş, ihsan; Gunduzoz, Meside; TUTKUN, Engin

Evaluation of the ambulatory arterial stiffness index in lead-exposed workers

Uğur Nadir KARAKULAK, (Ankara Occupational Diseases Hospital; Ankara-Turkey)

Ömer Hınç YILMAZ, (Ankara Occupational Diseases Hospital; Ankara-Turkey)

Engin TUTKUN, (Public Health, Bozok University Faculty of Medicine; Yozgat-Turkey)

İhsan ATEŞ, (Internal Medicine, Numune Research and Training Hospital; Ankara-Turkey)

Ceylan BAL, (Ankara Occupational Diseases Hospital; Ankara-Turkey)

Meside GÜNDÜZÖZ (Ankara Occupational Diseases Hospital; Ankara-Turkey)

The Anatolian Journal of Cardiology

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Yıl: 2017 Cilt: 18 Sayı: 1 Sayfa Aralığı: 10 - 14 Metin Dili: İngilizce İndeks Tarihi: 29-07-2022

Evaluation of the ambulatory arterial stiffness index in lead-exposed workers

Öz:

Objective: Lead exposure has been associated with various cardiovascular disorders. It may also cause increased inflammation and fibrosis in the arterial system resulting in an increase in arterial stiffness. In this study, the ambulatory arterial stiffness index (AASI), which is a technique that measures arterial stiffness, was evaluated in occupationally lead-exposed workers.Methods: In this cross-sectional study, 68 lead-exposed workers without known cardiovascular risk factors and 68 healthy subjects were evaluated according to the 24-hour ambulatory blood pressure monitorization (ABPM) profiles and blood and 24-hour urine lead levels. A regression slope of diastolic over systolic blood pressure (BP) was computed in each participant. AASI was defined as 1 minus the regression slope.Results: There were no significant differences in terms of baseline demographic, clinical, echocardiographic characteristics, and ABPM profiles between the groups. In lead-exposed workers, the mean age was 34.7±8.1 years, and the median blood and urine lead levels were 40.5 μg/dL and 34.9 μg/L, respectively. AASI was 0.42±0.10 in lead-exposed workers and 0.37±0.10 in control subjects (p=0.007). In correlation analysis, AASI was correlated with both blood (r=0.417, p<0.001) and urine lead (r=0.242, p=0.047) levels. In regression analysis, blood lead level was found to be associated with AASI (β=0.086, p<0.001).Conclusion: AASI, which is an indicator of arterial stiffness, was found to be higher in lead-exposed workers than in healthy individuals. Increased AASI may be considered an early sign of arterial involvement in case of lead exposure

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APA	KARAKULAK U, Yılmaz Ö, TUTKUN E, ateş i, bal c, Gunduzoz M (2017). Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. , 10 - 14.
Chicago	KARAKULAK Uğur Nadir,Yılmaz Ömer Hinç,TUTKUN Engin,ateş ihsan,bal ceylan,Gunduzoz Meside Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. (2017): 10 - 14.
MLA	KARAKULAK Uğur Nadir,Yılmaz Ömer Hinç,TUTKUN Engin,ateş ihsan,bal ceylan,Gunduzoz Meside Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. , 2017, ss.10 - 14.
AMA	KARAKULAK U,Yılmaz Ö,TUTKUN E,ateş i,bal c,Gunduzoz M Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. . 2017; 10 - 14.
Vancouver	KARAKULAK U,Yılmaz Ö,TUTKUN E,ateş i,bal c,Gunduzoz M Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. . 2017; 10 - 14.
IEEE	KARAKULAK U,Yılmaz Ö,TUTKUN E,ateş i,bal c,Gunduzoz M "Evaluation of the ambulatory arterial stiffness index in lead-exposed workers." , ss.10 - 14, 2017.
ISNAD	KARAKULAK, Uğur Nadir vd. "Evaluation of the ambulatory arterial stiffness index in lead-exposed workers". (2017), 10-14.

APA	KARAKULAK U, Yılmaz Ö, TUTKUN E, ateş i, bal c, Gunduzoz M (2017). Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. The Anatolian Journal of Cardiology, 18(1), 10 - 14.
Chicago	KARAKULAK Uğur Nadir,Yılmaz Ömer Hinç,TUTKUN Engin,ateş ihsan,bal ceylan,Gunduzoz Meside Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. The Anatolian Journal of Cardiology 18, no.1 (2017): 10 - 14.
MLA	KARAKULAK Uğur Nadir,Yılmaz Ömer Hinç,TUTKUN Engin,ateş ihsan,bal ceylan,Gunduzoz Meside Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. The Anatolian Journal of Cardiology, vol.18, no.1, 2017, ss.10 - 14.
AMA	KARAKULAK U,Yılmaz Ö,TUTKUN E,ateş i,bal c,Gunduzoz M Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. The Anatolian Journal of Cardiology. 2017; 18(1): 10 - 14.
Vancouver	KARAKULAK U,Yılmaz Ö,TUTKUN E,ateş i,bal c,Gunduzoz M Evaluation of the ambulatory arterial stiffness index in lead-exposed workers. The Anatolian Journal of Cardiology. 2017; 18(1): 10 - 14.
IEEE	KARAKULAK U,Yılmaz Ö,TUTKUN E,ateş i,bal c,Gunduzoz M "Evaluation of the ambulatory arterial stiffness index in lead-exposed workers." The Anatolian Journal of Cardiology, 18, ss.10 - 14, 2017.
ISNAD	KARAKULAK, Uğur Nadir vd. "Evaluation of the ambulatory arterial stiffness index in lead-exposed workers". The Anatolian Journal of Cardiology 18/1 (2017), 10-14.