Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding

KOBTAN, Abdelrahman; MOURAD, Heba; KALLA, Ferial El; ELZEFTAWY, Asmaa; MANSOUR, Loai

Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding

Asmaa ELZEFTAWY, (Department of Tropical Medicine and Infectious Diseases, Tanta University School of Medicine, Tanta, Egypt)

Loai MANSOUR, (Department of Tropical Medicine and Infectious Diseases, Tanta University School of Medicine, Tanta, Egypt)

Abdelrahman KOBTAN, (Department of Tropical Medicine and Infectious Diseases, Tanta University School of Medicine, Tanta, Egypt)

Heba MOURAD, (Department of Clinical Pathology, Tanta University School of Medicine, Tanta, Egypt)

Ferial El KALLA (Department of Tropical Medicine and Infectious Diseases, Tanta University School of Medicine, Tanta, Egypt)

Turkish Journal of Gastroenterology

3 0

Yıl: 2019 Cilt: 30 Sayı: 1 Sayfa Aralığı: 59 - 65 Metin Dili: İngilizce İndeks Tarihi: 21-05-2019

Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding

Öz:

Background/Aims: The development of esophageal varices (EV) and resultant bleeding are the most critical complications of portalhypertension. Upper gastrointestinal endoscopy is the gold standard for diagnosis of EV. To find a non-invasive method for diagnosis ofEV and to predict the bleeding risk is appealing and would decrease the cost and discomfort of upper endoscopy. The aim of our studywas to evaluate the blood ammonia level as a predictor of the presence of EV and of a high risk of bleeding.Materials and Methods: In this cross-sectional study, a total of 359 patients with cirrhosis were examined for the presence of EV by upper endoscopy. Abdominal ultrasonography, calculation of the Child-Pugh score, and measurement of blood ammonia were performedfor each patient.Results: The blood ammonia level was significantly higher in patients with EV than in those without it (p<0.001), and in patients with ahigh risk of variceal bleeding than in those with a low risk (p=0.026).Conclusion: An increased blood ammonia level and splenic vein diameter are predictors for the presence of EV and bleeding risk factors.The blood ammonia level may be clinically useful as it correlates with and is an independent predictor for both the endoscopic risk signsand risk factors of bleeding, and therefore, it could be used in patients with cirrhosis to decrease the number of screening endoscopiesthey are subjected to.

Anahtar Kelime:

Konular: Gastroenteroloji ve Hepatoloji

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ELZEFTAWY A, MANSOUR L, KOBTAN A, MOURAD H, KALLA F (2019). Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. , 59 - 65.
Chicago	ELZEFTAWY Asmaa,MANSOUR Loai,KOBTAN Abdelrahman,MOURAD Heba,KALLA Ferial El Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. (2019): 59 - 65.
MLA	ELZEFTAWY Asmaa,MANSOUR Loai,KOBTAN Abdelrahman,MOURAD Heba,KALLA Ferial El Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. , 2019, ss.59 - 65.
AMA	ELZEFTAWY A,MANSOUR L,KOBTAN A,MOURAD H,KALLA F Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. . 2019; 59 - 65.
Vancouver	ELZEFTAWY A,MANSOUR L,KOBTAN A,MOURAD H,KALLA F Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. . 2019; 59 - 65.
IEEE	ELZEFTAWY A,MANSOUR L,KOBTAN A,MOURAD H,KALLA F "Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding." , ss.59 - 65, 2019.
ISNAD	ELZEFTAWY, Asmaa vd. "Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding". (2019), 59-65.

APA	ELZEFTAWY A, MANSOUR L, KOBTAN A, MOURAD H, KALLA F (2019). Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. Turkish Journal of Gastroenterology, 30(1), 59 - 65.
Chicago	ELZEFTAWY Asmaa,MANSOUR Loai,KOBTAN Abdelrahman,MOURAD Heba,KALLA Ferial El Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. Turkish Journal of Gastroenterology 30, no.1 (2019): 59 - 65.
MLA	ELZEFTAWY Asmaa,MANSOUR Loai,KOBTAN Abdelrahman,MOURAD Heba,KALLA Ferial El Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. Turkish Journal of Gastroenterology, vol.30, no.1, 2019, ss.59 - 65.
AMA	ELZEFTAWY A,MANSOUR L,KOBTAN A,MOURAD H,KALLA F Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. Turkish Journal of Gastroenterology. 2019; 30(1): 59 - 65.
Vancouver	ELZEFTAWY A,MANSOUR L,KOBTAN A,MOURAD H,KALLA F Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding. Turkish Journal of Gastroenterology. 2019; 30(1): 59 - 65.
IEEE	ELZEFTAWY A,MANSOUR L,KOBTAN A,MOURAD H,KALLA F "Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding." Turkish Journal of Gastroenterology, 30, ss.59 - 65, 2019.
ISNAD	ELZEFTAWY, Asmaa vd. "Evaluation of the blood ammonia level as a non-invasive predictor for the presence of esophageal varices and the risk of bleeding". Turkish Journal of Gastroenterology 30/1 (2019), 59-65.