Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer
Yıl: 2018 Cilt: 29 Sayı: 1 Sayfa Aralığı: 57 - 58 Metin Dili: İngilizce İndeks Tarihi: 05-04-2019
Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer
Öz: Capecitabine is an oral agent that is used either as single agent or incombination therapy. Therapy related acute myeloblastic leukemia aftercapecitabine use is rarely reported. We presented a 39-year-old woman withmetastatic breast cancer. She admitted with acute myelomonocytic leukemiaafter treating with oral Capecitabine. t(10;11)(q22;q23) was determined inconventional cytogenetic analysis. She achieved complete remission withintensive chemotherapy but relapse developed. She died although the salvagechemotherapy. To our knowledge our patients is the first report with t-AMLwith t(10;11)(q22;q23) secondary to Capecitabine use for breast cancertreatment. Capecitabine should be carefully used especially in patients withhigh risk for t-AML.
Anahtar Kelime: Meme Kanserli bir Hastada Capecitabin İlişkili ve t(10;11) (q22;q23) Pozitif Akut Myeloblastik Lösemi
Öz: Capesitabin tek başına veya kombinasyon tedavileri ile kullanılabilen ve oral yolla kullanılan bir tedavi ajanıdır. Capesitabin kullanımı ile ilişkilendirilen tedavi ilişkili lösemi olguları oldukça nadirdir. Biz 39 yaşında metastatic meme kanserli bir olguyu sunduk. Hasta Capesitabin ile tedavi edildikten sonra akut myelomonositik lösemi ile başvurdu. t(10;11)(q22;q23) konvansiyonel sitogenetik çalışmada saptandı. İndüksiyon kemoterapi ile remisyon sağlanmasına karşın daha sonra relaps gelişti. Kurtarma kemoterapi verildi, ancak hasta kaybedildi. Bu vaka Capesitabin kullanımı sonrası t(10;11)(q22;q23) ile birlikte t-AML geliştiğini gösteren ilk rapordur. T-AML gelişimi yüksek hastalar Capesitabin kullanımı sırasında yakından izlenmelidir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
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| APA | OZKURT Z, ÖCAL R, pepeler m, ÜLKÜDEN B (2018). Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. , 57 - 58. |
| Chicago | OZKURT ZÜBEYDE NUR,ÖCAL Ramazan,pepeler mehmet sezgin,ÜLKÜDEN Burcu Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. (2018): 57 - 58. |
| MLA | OZKURT ZÜBEYDE NUR,ÖCAL Ramazan,pepeler mehmet sezgin,ÜLKÜDEN Burcu Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. , 2018, ss.57 - 58. |
| AMA | OZKURT Z,ÖCAL R,pepeler m,ÜLKÜDEN B Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. . 2018; 57 - 58. |
| Vancouver | OZKURT Z,ÖCAL R,pepeler m,ÜLKÜDEN B Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. . 2018; 57 - 58. |
| IEEE | OZKURT Z,ÖCAL R,pepeler m,ÜLKÜDEN B "Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer." , ss.57 - 58, 2018. |
| ISNAD | OZKURT, ZÜBEYDE NUR vd. "Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer". (2018), 57-58. |
| APA | OZKURT Z, ÖCAL R, pepeler m, ÜLKÜDEN B (2018). Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. Gazi Medical Journal, 29(1), 57 - 58. |
| Chicago | OZKURT ZÜBEYDE NUR,ÖCAL Ramazan,pepeler mehmet sezgin,ÜLKÜDEN Burcu Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. Gazi Medical Journal 29, no.1 (2018): 57 - 58. |
| MLA | OZKURT ZÜBEYDE NUR,ÖCAL Ramazan,pepeler mehmet sezgin,ÜLKÜDEN Burcu Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. Gazi Medical Journal, vol.29, no.1, 2018, ss.57 - 58. |
| AMA | OZKURT Z,ÖCAL R,pepeler m,ÜLKÜDEN B Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. Gazi Medical Journal. 2018; 29(1): 57 - 58. |
| Vancouver | OZKURT Z,ÖCAL R,pepeler m,ÜLKÜDEN B Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer. Gazi Medical Journal. 2018; 29(1): 57 - 58. |
| IEEE | OZKURT Z,ÖCAL R,pepeler m,ÜLKÜDEN B "Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer." Gazi Medical Journal, 29, ss.57 - 58, 2018. |
| ISNAD | OZKURT, ZÜBEYDE NUR vd. "Capecitabine Induced Therapy Related Acute Myeloblastic Leukemia with t(10;11) (q22;q23) in a Patient with Breast Cancer". Gazi Medical Journal 29/1 (2018), 57-58. |
